diff --git a/requirements.txt b/requirements.txt
index 113d574a..525bb88b 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -6,6 +6,6 @@ Cython==0.29.30
 cyvcf2==0.30.15
 uvloop==0.16.0
 aiocache==0.11.1
-ujson==5.2.0
+ujson==5.3.0
 Authlib==1.0.1
 gunicorn==20.1.0
diff --git a/setup.py b/setup.py
index ebdc2d45..a5cf44c7 100644
--- a/setup.py
+++ b/setup.py
@@ -46,7 +46,7 @@
         "uvloop==0.16.0",
         "cyvcf2==0.30.15",
         "aiocache==0.11.1",
-        "ujson==5.2.0",
+        "ujson==5.3.0",
     ],
     extras_require={
         "vcf": [