diff --git a/requirements.txt b/requirements.txt
index 0688cb6f..be394039 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -2,7 +2,7 @@ aiohttp==3.8.3
 aiohttp-cors==0.7.0
 asyncpg==0.27.0
 jsonschema==4.17.3
-Cython==0.29.32
+Cython==0.29.33
 cyvcf2==0.30.18
 uvloop==0.17.0
 aiocache==0.11.1
diff --git a/setup.py b/setup.py
index 4a632cbb..325d7fb4 100644
--- a/setup.py
+++ b/setup.py
@@ -52,7 +52,7 @@
         "vcf": [
             "numpy==1.24.1",
             "cyvcf2==0.30.18",
-            "Cython==0.29.32",
+            "Cython==0.29.33",
         ],
         "test": [
             "coverage==7.0.2",