diff --git a/CMake/itkVersion.cmake b/CMake/itkVersion.cmake
index e4100f739a0..e9509ab406a 100644
--- a/CMake/itkVersion.cmake
+++ b/CMake/itkVersion.cmake
@@ -1,4 +1,4 @@
 # ITK version number components.
-set(ITK_VERSION_MAJOR "5")
-set(ITK_VERSION_MINOR "4")
+set(ITK_VERSION_MAJOR "6")
+set(ITK_VERSION_MINOR "0")
 set(ITK_VERSION_PATCH "0")