diff --git a/generative/losses/perceptual.py b/generative/losses/perceptual.py
index 68b94d75..5a3640b8 100644
--- a/generative/losses/perceptual.py
+++ b/generative/losses/perceptual.py
@@ -45,8 +45,11 @@ def __init__(
         if spatial_dims not in [2, 3]:
             raise NotImplementedError("Perceptual loss is implemented only in 2D and 3D.")
 
-        if spatial_dims == 2 and "medicalnet_" in network_type:
-            raise ValueError("MedicalNet networks are only compatible with ``spatial_dims=3``.")
+        if (spatial_dims == 2 or is_fake_3d) and "medicalnet_" in network_type:
+            raise ValueError(
+                "MedicalNet networks are only compatible with ``spatial_dims=3``."
+                "Argument is_fake_3d must be set to False."
+            )
 
         self.spatial_dims = spatial_dims
         if spatial_dims == 3 and is_fake_3d is False: