diff --git a/monai/data/nifti_saver.py b/monai/data/nifti_saver.py
index 34df819d32..0ff719023c 100644
--- a/monai/data/nifti_saver.py
+++ b/monai/data/nifti_saver.py
@@ -9,7 +9,7 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-from typing import Dict, Optional, Sequence, Union
+from typing import Dict, Optional, Union
 
 import numpy as np
 import torch
@@ -93,12 +93,7 @@ def __init__(
         self.squeeze_end_dims = squeeze_end_dims
         self.data_root_dir = data_root_dir
 
-    def save(
-        self,
-        data: Union[torch.Tensor, np.ndarray],
-        meta_data: Optional[Dict] = None,
-        patch_index: Optional[int] = None,
-    ) -> None:
+    def save(self, data: Union[torch.Tensor, np.ndarray], meta_data: Optional[Dict] = None) -> None:
         """
         Save data into a Nifti file.
         The meta_data could optionally have the following keys:
@@ -107,6 +102,7 @@ def save(
             - ``'original_affine'`` -- for data orientation handling, defaulting to an identity matrix.
             - ``'affine'`` -- for data output affine, defaulting to an identity matrix.
             - ``'spatial_shape'`` -- for data output shape.
+            - ``'patch_index'`` -- if the data is a patch of big image, append the patch index to filename.
 
         When meta_data is specified, the saver will try to resample batch data from the space
         defined by "affine" to the space defined by "original_affine".
@@ -117,7 +113,6 @@ def save(
             data: target data content that to be saved as a NIfTI format file.
                 Assuming the data shape starts with a channel dimension and followed by spatial dimensions.
             meta_data: the meta data information corresponding to the data.
-            patch_index: if the data is a patch of big image, need to append the patch index to filename.
 
         See Also
             :py:meth:`monai.data.nifti_writer.write_nifti`
@@ -127,6 +122,7 @@ def save(
         original_affine = meta_data.get("original_affine", None) if meta_data else None
         affine = meta_data.get("affine", None) if meta_data else None
         spatial_shape = meta_data.get("spatial_shape", None) if meta_data else None
+        patch_index = meta_data.get(Key.PATCH_INDEX, None) if meta_data else None
 
         if isinstance(data, torch.Tensor):
             data = data.detach().cpu().numpy()
@@ -158,12 +154,7 @@ def save(
             output_dtype=self.output_dtype,
         )
 
-    def save_batch(
-        self,
-        batch_data: Union[torch.Tensor, np.ndarray],
-        meta_data: Optional[Dict] = None,
-        patch_indice: Optional[Sequence[int]] = None,
-    ) -> None:
+    def save_batch(self, batch_data: Union[torch.Tensor, np.ndarray], meta_data: Optional[Dict] = None) -> None:
         """
         Save a batch of data into Nifti format files.
 
@@ -180,11 +171,7 @@ def save_batch(
         Args:
             batch_data: target batch data content that save into NIfTI format.
             meta_data: every key-value in the meta_data is corresponding to a batch of data.
-            patch_indice: if the data is a patch of big image, need to append the patch index to filename.
+
         """
         for i, data in enumerate(batch_data):  # save a batch of files
-            self.save(
-                data=data,
-                meta_data={k: meta_data[k][i] for k in meta_data} if meta_data is not None else None,
-                patch_index=patch_indice[i] if patch_indice is not None else None,
-            )
+            self.save(data=data, meta_data={k: meta_data[k][i] for k in meta_data} if meta_data is not None else None)
diff --git a/monai/data/png_saver.py b/monai/data/png_saver.py
index 17087fcaca..880f6b204f 100644
--- a/monai/data/png_saver.py
+++ b/monai/data/png_saver.py
@@ -9,7 +9,7 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-from typing import Dict, Optional, Sequence, Union
+from typing import Dict, Optional, Union
 
 import numpy as np
 import torch
@@ -71,18 +71,14 @@ def __init__(
 
         self._data_index = 0
 
-    def save(
-        self,
-        data: Union[torch.Tensor, np.ndarray],
-        meta_data: Optional[Dict] = None,
-        patch_index: Optional[int] = None,
-    ) -> None:
+    def save(self, data: Union[torch.Tensor, np.ndarray], meta_data: Optional[Dict] = None) -> None:
         """
         Save data into a png file.
         The meta_data could optionally have the following keys:
 
             - ``'filename_or_obj'`` -- for output file name creation, corresponding to filename or object.
             - ``'spatial_shape'`` -- for data output shape.
+            - ``'patch_index'`` -- if the data is a patch of big image, append the patch index to filename.
 
         If meta_data is None, use the default index (starting from 0) as the filename.
 
@@ -92,7 +88,6 @@ def save(
                 Shape of the spatial dimensions (C,H,W).
                 C should be 1, 3 or 4
             meta_data: the meta data information corresponding to the data.
-            patch_index: if the data is a patch of big image, need to append the patch index to filename.
 
         Raises:
             ValueError: When ``data`` channels is not one of [1, 3, 4].
@@ -104,6 +99,7 @@ def save(
         filename = meta_data[Key.FILENAME_OR_OBJ] if meta_data else str(self._data_index)
         self._data_index += 1
         spatial_shape = meta_data.get("spatial_shape", None) if meta_data and self.resample else None
+        patch_index = meta_data.get(Key.PATCH_INDEX, None) if meta_data else None
 
         if isinstance(data, torch.Tensor):
             data = data.detach().cpu().numpy()
@@ -126,22 +122,13 @@ def save(
             scale=self.scale,
         )
 
-    def save_batch(
-        self,
-        batch_data: Union[torch.Tensor, np.ndarray],
-        meta_data: Optional[Dict] = None,
-        patch_indice: Optional[Sequence[int]] = None,
-    ) -> None:
+    def save_batch(self, batch_data: Union[torch.Tensor, np.ndarray], meta_data: Optional[Dict] = None) -> None:
         """Save a batch of data into png format files.
 
         Args:
             batch_data: target batch data content that save into png format.
             meta_data: every key-value in the meta_data is corresponding to a batch of data.
-            patch_indice: if the data is a patch of big image, need to append the patch index to filename.
+
         """
         for i, data in enumerate(batch_data):  # save a batch of files
-            self.save(
-                data=data,
-                meta_data={k: meta_data[k][i] for k in meta_data} if meta_data is not None else None,
-                patch_index=patch_indice[i] if patch_indice is not None else None,
-            )
+            self.save(data=data, meta_data={k: meta_data[k][i] for k in meta_data} if meta_data is not None else None)
diff --git a/monai/handlers/segmentation_saver.py b/monai/handlers/segmentation_saver.py
index 7df10b9dad..9ee7ca67f9 100644
--- a/monai/handlers/segmentation_saver.py
+++ b/monai/handlers/segmentation_saver.py
@@ -16,9 +16,7 @@
 
 from monai.config import DtypeLike
 from monai.transforms import SaveImage
-from monai.utils import GridSampleMode, GridSamplePadMode
-from monai.utils import ImageMetaKey as Key
-from monai.utils import InterpolateMode, exact_version, optional_import
+from monai.utils import GridSampleMode, GridSamplePadMode, InterpolateMode, exact_version, optional_import
 
 Events, _ = optional_import("ignite.engine", "0.4.4", exact_version, "Events")
 if TYPE_CHECKING:
@@ -145,6 +143,5 @@ def __call__(self, engine: Engine) -> None:
         """
         meta_data = self.batch_transform(engine.state.batch)
         engine_output = self.output_transform(engine.state.output)
-        patch_indice = engine.state.batch.get(Key.PATCH_INDEX, None)
-        self._saver(engine_output, meta_data, patch_indice)
+        self._saver(engine_output, meta_data)
         self.logger.info("saved all the model outputs into files.")
diff --git a/monai/transforms/croppad/dictionary.py b/monai/transforms/croppad/dictionary.py
index 428e35335c..1d4fcfdb1f 100644
--- a/monai/transforms/croppad/dictionary.py
+++ b/monai/transforms/croppad/dictionary.py
@@ -483,7 +483,7 @@ class RandSpatialCropSamplesd(RandomizableTransform, MapTransform):
     Crop image with random size or specific size ROI to generate a list of N samples.
     It can crop at a random position as center or at the image center. And allows to set
     the minimum size to limit the randomly generated ROI. Suppose all the expected fields
-    specified by `keys` have same shape.
+    specified by `keys` have same shape, and add `patch_index` to the corresponding meta data.
     It will return a list of dictionaries for all the cropped images.
 
     Args:
@@ -495,6 +495,9 @@ class RandSpatialCropSamplesd(RandomizableTransform, MapTransform):
         random_center: crop at random position as center or the image center.
         random_size: crop with random size or specific size ROI.
             The actual size is sampled from `randint(roi_size, img_size)`.
+        meta_key_postfix: use `key_{postfix}` to to fetch the meta data according to the key data,
+            default is `meta_dict`, the meta data is a dictionary object.
+            used to add `patch_index` to the meta dict.
         allow_missing_keys: don't raise exception if key is missing.
 
     Raises:
@@ -509,6 +512,7 @@ def __init__(
         num_samples: int,
         random_center: bool = True,
         random_size: bool = True,
+        meta_key_postfix: str = "meta_dict",
         allow_missing_keys: bool = False,
     ) -> None:
         RandomizableTransform.__init__(self, prob=1.0, do_transform=True)
@@ -517,6 +521,7 @@ def __init__(
             raise ValueError(f"num_samples must be positive, got {num_samples}.")
         self.num_samples = num_samples
         self.cropper = RandSpatialCropd(keys, roi_size, random_center, random_size, allow_missing_keys)
+        self.meta_key_postfix = meta_key_postfix
 
     def set_random_state(
         self, seed: Optional[int] = None, state: Optional[np.random.RandomState] = None
@@ -530,9 +535,15 @@ def randomize(self, data: Optional[Any] = None) -> None:
 
     def __call__(self, data: Mapping[Hashable, np.ndarray]) -> List[Dict[Hashable, np.ndarray]]:
         ret = []
+        d = dict(data)
         for i in range(self.num_samples):
-            cropped = self.cropper(data)
-            cropped[Key.PATCH_INDEX] = i  # type: ignore
+            cropped = self.cropper(d)
+            # add `patch_index` to the meta data
+            for key in self.key_iterator(d):
+                meta_data_key = f"{key}_{self.meta_key_postfix}"
+                if meta_data_key not in cropped:
+                    cropped[meta_data_key] = {}  # type: ignore
+                cropped[meta_data_key][Key.PATCH_INDEX] = i
             ret.append(cropped)
         return ret
 
@@ -687,6 +698,8 @@ class RandCropByPosNegLabeld(RandomizableTransform, MapTransform):
     Dictionary-based version :py:class:`monai.transforms.RandCropByPosNegLabel`.
     Crop random fixed sized regions with the center being a foreground or background voxel
     based on the Pos Neg Ratio.
+    Suppose all the expected fields specified by `keys` have same shape,
+    and add `patch_index` to the corresponding meta data.
     And will return a list of dictionaries for all the cropped images.
 
     Args:
@@ -712,6 +725,9 @@ class RandCropByPosNegLabeld(RandomizableTransform, MapTransform):
             `image_threshold`, and randomly select crop centers based on them, need to provide `fg_indices_key`
             and `bg_indices_key` together, expect to be 1 dim array of spatial indices after flattening.
             a typical usage is to call `FgBgToIndicesd` transform first and cache the results.
+        meta_key_postfix: use `key_{postfix}` to to fetch the meta data according to the key data,
+            default is `meta_dict`, the meta data is a dictionary object.
+            used to add `patch_index` to the meta dict.
         allow_missing_keys: don't raise exception if key is missing.
 
     Raises:
@@ -732,6 +748,7 @@ def __init__(
         image_threshold: float = 0.0,
         fg_indices_key: Optional[str] = None,
         bg_indices_key: Optional[str] = None,
+        meta_key_postfix: str = "meta_dict",
         allow_missing_keys: bool = False,
     ) -> None:
         RandomizableTransform.__init__(self)
@@ -748,6 +765,7 @@ def __init__(
         self.image_threshold = image_threshold
         self.fg_indices_key = fg_indices_key
         self.bg_indices_key = bg_indices_key
+        self.meta_key_postfix = meta_key_postfix
         self.centers: Optional[List[List[np.ndarray]]] = None
 
     def randomize(
@@ -789,8 +807,12 @@ def __call__(self, data: Mapping[Hashable, np.ndarray]) -> List[Dict[Hashable, n
             # fill in the extra keys with unmodified data
             for key in set(data.keys()).difference(set(self.keys)):
                 results[i][key] = data[key]
-            # add patch index in the meta data
-            results[i][Key.PATCH_INDEX] = i  # type: ignore
+            # add `patch_index` to the meta data
+            for key in self.key_iterator(d):
+                meta_data_key = f"{key}_{self.meta_key_postfix}"
+                if meta_data_key not in results[i]:
+                    results[i][meta_data_key] = {}  # type: ignore
+                results[i][meta_data_key][Key.PATCH_INDEX] = i
 
         return results
 
diff --git a/monai/transforms/io/array.py b/monai/transforms/io/array.py
index b138b97cb2..7a7fcb8cda 100644
--- a/monai/transforms/io/array.py
+++ b/monai/transforms/io/array.py
@@ -269,19 +269,14 @@ def __init__(
 
         self.save_batch = save_batch
 
-    def __call__(
-        self,
-        img: Union[torch.Tensor, np.ndarray],
-        meta_data: Optional[Dict] = None,
-        patch_index=None,  # type is Union[Sequence[int], int, None], can't be compatible with save and save_batch
-    ):
+    def __call__(self, img: Union[torch.Tensor, np.ndarray], meta_data: Optional[Dict] = None):
         """
         Args:
             img: target data content that save into file.
             meta_data: key-value pairs of meta_data corresponding to the data.
-            patch_index: if the data is a patch of big image, need to append the patch index to filename.
+
         """
         if self.save_batch:
-            self.saver.save_batch(img, meta_data, patch_index)
+            self.saver.save_batch(img, meta_data)
         else:
-            self.saver.save(img, meta_data, patch_index)
+            self.saver.save(img, meta_data)
diff --git a/monai/transforms/io/dictionary.py b/monai/transforms/io/dictionary.py
index 5b8f0a41d3..58d6431c74 100644
--- a/monai/transforms/io/dictionary.py
+++ b/monai/transforms/io/dictionary.py
@@ -23,9 +23,7 @@
 from monai.data.image_reader import ImageReader
 from monai.transforms.io.array import LoadImage, SaveImage
 from monai.transforms.transform import MapTransform
-from monai.utils import GridSampleMode, GridSamplePadMode
-from monai.utils import ImageMetaKey as Key
-from monai.utils import InterpolateMode
+from monai.utils import GridSampleMode, GridSamplePadMode, InterpolateMode
 
 __all__ = [
     "LoadImaged",
@@ -229,7 +227,7 @@ def __call__(self, data):
         d = dict(data)
         for key in self.key_iterator(d):
             meta_data = d[f"{key}_{self.meta_key_postfix}"] if self.meta_key_postfix is not None else None
-            self._saver(img=d[key], meta_data=meta_data, patch_index=d.get(Key.PATCH_INDEX, None))
+            self._saver(img=d[key], meta_data=meta_data)
         return d
 
 
diff --git a/tests/test_rand_crop_by_pos_neg_labeld.py b/tests/test_rand_crop_by_pos_neg_labeld.py
index 2744d729a1..d52ba900ac 100644
--- a/tests/test_rand_crop_by_pos_neg_labeld.py
+++ b/tests/test_rand_crop_by_pos_neg_labeld.py
@@ -92,7 +92,7 @@ def test_type_shape(self, input_param, input_data, expected_type, expected_shape
         self.assertTupleEqual(result[0]["extral"].shape, expected_shape)
         self.assertTupleEqual(result[0]["label"].shape, expected_shape)
         for i, item in enumerate(result):
-            self.assertEqual(item["patch_index"], i)
+            self.assertEqual(item["image_meta_dict"]["patch_index"], i)
 
 
 if __name__ == "__main__":
diff --git a/tests/test_rand_spatial_crop_samplesd.py b/tests/test_rand_spatial_crop_samplesd.py
index 5b745add18..09688f44b7 100644
--- a/tests/test_rand_spatial_crop_samplesd.py
+++ b/tests/test_rand_spatial_crop_samplesd.py
@@ -71,7 +71,8 @@ def test_shape(self, input_param, input_data, expected_shape, expected_last):
             self.assertTupleEqual(item["img"].shape, expected)
             self.assertTupleEqual(item["seg"].shape, expected)
         for i, item in enumerate(result):
-            self.assertEqual(item["patch_index"], i)
+            self.assertEqual(item["img_meta_dict"]["patch_index"], i)
+            self.assertEqual(item["seg_meta_dict"]["patch_index"], i)
         np.testing.assert_allclose(item["img"], expected_last["img"])
         np.testing.assert_allclose(item["seg"], expected_last["seg"])
 
diff --git a/tests/test_save_imaged.py b/tests/test_save_imaged.py
index b5293473c2..d6536b3d51 100644
--- a/tests/test_save_imaged.py
+++ b/tests/test_save_imaged.py
@@ -117,7 +117,7 @@ def test_saved_content(self, test_data, output_ext, resample, save_batch):
                     filepath = os.path.join("testfile" + str(i), "testfile" + str(i) + "_trans" + output_ext)
                     self.assertTrue(os.path.exists(os.path.join(tempdir, filepath)))
             else:
-                patch_index = test_data.get("patch_index", None)
+                patch_index = test_data["img_meta_dict"].get("patch_index", None)
                 patch_index = f"_{patch_index}" if patch_index is not None else ""
                 filepath = os.path.join("testfile0", "testfile0" + "_trans" + patch_index + output_ext)
                 self.assertTrue(os.path.exists(os.path.join(tempdir, filepath)))