diff --git a/Assets/Prefabs/UI/SettingsMenu/Menus/EphysLinkMenu.prefab b/Assets/Prefabs/UI/SettingsMenu/Menus/EphysLinkMenu.prefab
index 748806e1..f683b830 100644
--- a/Assets/Prefabs/UI/SettingsMenu/Menus/EphysLinkMenu.prefab
+++ b/Assets/Prefabs/UI/SettingsMenu/Menus/EphysLinkMenu.prefab
@@ -2565,7 +2565,7 @@ MonoBehaviour:
     m_PressedTrigger: Pressed
     m_SelectedTrigger: Selected
     m_DisabledTrigger: Disabled
-  m_Interactable: 1
+  m_Interactable: 0
   m_TargetGraphic: {fileID: 6487466997665187127}
   toggleTransition: 1
   graphic: {fileID: 2477337667047670143}
diff --git a/Assets/Scripts/Pinpoint/UI/EphysCopilot/InsertionSelectionPanelHandler.cs b/Assets/Scripts/Pinpoint/UI/EphysCopilot/InsertionSelectionPanelHandler.cs
index a17906ee..14631bdf 100644
--- a/Assets/Scripts/Pinpoint/UI/EphysCopilot/InsertionSelectionPanelHandler.cs
+++ b/Assets/Scripts/Pinpoint/UI/EphysCopilot/InsertionSelectionPanelHandler.cs
@@ -246,13 +246,21 @@ public void UpdateTargetInsertionOptions()
                 .Select(probeManager => (probeManager.OverrideName ?? probeManager.name) + ": " +
                                         SurfaceCoordinateToString(probeManager.GetSurfaceCoordinateT())).ToList());
 
+            // Return early if no manipulator ID
+            if (ProbeManager.ManipulatorBehaviorController.ManipulatorID == null) return;
+
             // Restore selection (if possible)
             var selectedProbeManager = ManipulatorIDToSelectedTargetProbeManager.GetValueOrDefault(
                 ProbeManager.ManipulatorBehaviorController.ManipulatorID, null);
-            _targetInsertionDropdown.SetValueWithoutNotify(
-                _targetProbeManagerOptions.ToList()
-                    .IndexOf(selectedProbeManager) + 1
-            );
+            if (selectedProbeManager == null)
+                // Select none if no previous selection.
+                _targetInsertionDropdown.SetValueWithoutNotify(0);
+            else
+                _targetInsertionDropdown.SetValueWithoutNotify(
+                    _targetProbeManagerOptions.ToList()
+                        .IndexOf(selectedProbeManager) + 1
+                );
+
 
             // Color dropdown to match probe color
             if (!selectedProbeManager) return;
diff --git a/Assets/Scripts/Pinpoint/UI/EphysLinkSettings/EphysLinkSettings.cs b/Assets/Scripts/Pinpoint/UI/EphysLinkSettings/EphysLinkSettings.cs
index 8efdc807..ca48284b 100644
--- a/Assets/Scripts/Pinpoint/UI/EphysLinkSettings/EphysLinkSettings.cs
+++ b/Assets/Scripts/Pinpoint/UI/EphysLinkSettings/EphysLinkSettings.cs
@@ -85,15 +85,11 @@ private void UpdateConnectionPanel()
         private void UpdateManipulatorPanels()
         {
             // Default Copilot to be disabled unless the right manipulator type is found
-            _copilotToggle.interactable = false;
 
             if (CommunicationManager.Instance.IsConnected)
             {
                 CommunicationManager.Instance.GetManipulators((availableIDs, numAxes, _) =>
                 {
-                    // Enable Copilot button if using Sensapex or New Scale
-                    _copilotToggle.interactable = numAxes > 0;
-
                     // Keep track of handled manipulator panels
                     var handledManipulatorIds = new HashSet<string>();
 
@@ -232,6 +228,9 @@ public void ToggleCopilotPanel(bool isEnabled)
         public void InvokeShouldUpdateProbesListEvent()
         {
             ShouldUpdateProbesListEvent.Invoke();
+            
+            // Enable/Disable Copilot toggle based on if there are any probes that can be controlled by it.
+            _copilotToggle.interactable = LinkedProbes.Count > 0;
         }
 
         #endregion