diff --git a/src/wp-includes/class-wp-query.php b/src/wp-includes/class-wp-query.php
index 1f6f926b1a05e..dc596cb79a818 100644
--- a/src/wp-includes/class-wp-query.php
+++ b/src/wp-includes/class-wp-query.php
@@ -3088,10 +3088,12 @@ public function get_posts() {
 				$cache_args['update_post_meta_cache'],
 				$cache_args['update_post_term_cache'],
 				$cache_args['lazy_load_term_meta'],
-				$cache_args['update_menu_item_cache']
+				$cache_args['update_menu_item_cache'],
+				$cache_args['search_orderby_title']
 			);
 
 			$new_request = str_replace( $fields, "{$wpdb->posts}.*", $this->request );
+			$new_request = $wpdb->remove_placeholder_escape( $new_request );
 			$key         = md5( serialize( $cache_args ) . $new_request );
 
 			$last_changed = wp_cache_get_last_changed( 'posts' );
diff --git a/src/wp-includes/class-wpdb.php b/src/wp-includes/class-wpdb.php
index 88317f535e918..c021d606be7e0 100644
--- a/src/wp-includes/class-wpdb.php
+++ b/src/wp-includes/class-wpdb.php
@@ -2413,12 +2413,17 @@ public function log_query( $query, $query_time, $query_callstack, $query_start,
 	 * Generates and returns a placeholder escape string for use in queries returned by ::prepare().
 	 *
 	 * @since 4.8.3
+	 * @since 6.1.0 Added `$reset` parameter.
+	 *
+	 * @param bool $reset Optional. Whether to reset the placeholder. Default false.
 	 *
 	 * @return string String to escape placeholders.
 	 */
-	public function placeholder_escape() {
+	public function placeholder_escape( $reset = false ) {
 		static $placeholder;
-
+		if ( $reset ) {
+			$placeholder = null;
+		}
 		if ( ! $placeholder ) {
 			// If ext/hash is not present, compat.php's hash_hmac() does not support sha256.
 			$algo = function_exists( 'hash' ) ? 'sha256' : 'sha1';
diff --git a/tests/phpunit/tests/query/cacheResults.php b/tests/phpunit/tests/query/cacheResults.php
index 723c78a2bf0d3..d1c317ed32b23 100644
--- a/tests/phpunit/tests/query/cacheResults.php
+++ b/tests/phpunit/tests/query/cacheResults.php
@@ -191,6 +191,18 @@ public function data_query_cache() {
 					),
 				),
 			),
+			'cache meta query search'                     => array(
+				'args' => array(
+					'cache_results' => true,
+					'meta_query'    => array(
+						array(
+							'key'     => 'color',
+							'value'   => '00',
+							'compare' => 'LIKE',
+						),
+					),
+				),
+			),
 			'cache comment_count'                         => array(
 				'args' => array(
 					'cache_results' => true,
@@ -209,6 +221,12 @@ public function data_query_cache() {
 					),
 				),
 			),
+			'cache search query'                          => array(
+				'args' => array(
+					'cache_results' => true,
+					's'             => 'e',
+				),
+			),
 		);
 	}
 
@@ -827,6 +845,70 @@ public function test_query_cache_delete_meta() {
 		$this->assertNotSame( $query1->found_posts, $query2->found_posts );
 	}
 
+
+	/**
+	 * @ticket 56802
+	 */
+	public function test_query_cache_like_meta() {
+		global $wpdb;
+		$p1 = self::$posts[0];
+
+		$args        = array(
+			'cache_results' => true,
+			'fields'        => 'ids',
+			'meta_query'    => array(
+				array(
+					'key'     => 'color',
+					'value'   => '00',
+					'compare' => 'LIKE',
+				),
+			),
+		);
+		$query1      = new WP_Query();
+		$posts1      = $query1->query( $args );
+		$num_queries = get_num_queries();
+
+		// Force placeholder to be different.
+		$wpdb->placeholder_escape( true );
+
+		$query2 = new WP_Query();
+		$posts2 = $query2->query( $args );
+
+		$this->assertSame( $posts1, $posts2, 'Results of first and second query should be the same' );
+		$this->assertSame( $num_queries, get_num_queries(), 'Should not result in another database query.' );
+		$this->assertContains( $p1, $posts2, 'Result should contain post 0.' );
+		$this->assertSame( $query1->found_posts, $query2->found_posts, 'Found posts should match on both queries' );
+	}
+
+	/**
+	 * @ticket 56802
+	 */
+	public function test_query_cache_search() {
+		global $wpdb;
+		// Post 0 already has the category foo.
+		$p1 = self::$posts[1];
+
+		$args        = array(
+			'cache_results' => true,
+			'fields'        => 'ids',
+			's'             => 'e',
+		);
+		$query1      = new WP_Query();
+		$posts1      = $query1->query( $args );
+		$num_queries = get_num_queries();
+
+		// Force placeholder to be different.
+		$wpdb->placeholder_escape( true );
+
+		$query2 = new WP_Query();
+		$posts2 = $query2->query( $args );
+
+		$this->assertSame( $posts1, $posts2, 'Results of first and second query should be the same' );
+		$this->assertSame( $num_queries, get_num_queries(), 'Should not result in another database query.' );
+		$this->assertContains( $p1, $posts2, 'Result should contain post 0.' );
+		$this->assertSame( $query1->found_posts, $query2->found_posts, 'Found posts should match on both queries' );
+	}
+
 	/**
 	 * @ticket 22176
 	 */