diff --git a/cpp/cmake_modules/ThirdpartyToolchain.cmake b/cpp/cmake_modules/ThirdpartyToolchain.cmake
index 4518576b569..8fd070e771d 100644
--- a/cpp/cmake_modules/ThirdpartyToolchain.cmake
+++ b/cpp/cmake_modules/ThirdpartyToolchain.cmake
@@ -3657,8 +3657,25 @@ macro(build_grpc)
   # Yuck, see https://stackoverflow.com/a/45433229/776560
   string(REPLACE ";" "|" GRPC_PREFIX_PATH_ALT_SEP "${GRPC_CMAKE_PREFIX}")
 
+  set(GRPC_C_FLAGS "${EP_C_FLAGS}")
+  set(GRPC_CXX_FLAGS "${EP_CXX_FLAGS}")
+  if(NOT MSVC)
+    # Negate warnings that gRPC cannot build under
+    # See https://github.com/grpc/grpc/issues/29417
+    set(GRPC_C_FLAGS
+        "${GRPC_C_FLAGS} -Wno-attributes -Wno-format-security -Wno-unknown-warning-option"
+    )
+    set(GRPC_CXX_FLAGS
+        "${GRPC_CXX_FLAGS} -Wno-attributes -Wno-format-security -Wno-unknown-warning-option"
+    )
+  endif()
+
   set(GRPC_CMAKE_ARGS
       "${EP_COMMON_CMAKE_ARGS}"
+      "-DCMAKE_C_FLAGS=${GRPC_C_FLAGS}"
+      "-DCMAKE_CXX_FLAGS=${GRPC_CXX_FLAGS}"
+      "-DCMAKE_C_FLAGS_${UPPERCASE_BUILD_TYPE}=${GRPC_C_FLAGS}"
+      "-DCMAKE_CXX_FLAGS_${UPPERCASE_BUILD_TYPE}=${GRPC_CXX_FLAGS}"
       -DCMAKE_PREFIX_PATH='${GRPC_PREFIX_PATH_ALT_SEP}'
       -DgRPC_ABSL_PROVIDER=package
       -DgRPC_BUILD_CSHARP_EXT=OFF