diff --git a/js/src/Arrow.dom.ts b/js/src/Arrow.dom.ts
index cdb4171162f..f4b8beb0a9b 100644
--- a/js/src/Arrow.dom.ts
+++ b/js/src/Arrow.dom.ts
@@ -24,14 +24,18 @@ import { builderThroughDOMStream } from './io/whatwg/builder.js';
 import { recordBatchReaderThroughDOMStream } from './io/whatwg/reader.js';
 import { recordBatchWriterThroughDOMStream } from './io/whatwg/writer.js';
 
-streamAdapters.toDOMStream = toDOMStream;
-Builder['throughDOM'] = builderThroughDOMStream;
-RecordBatchReader['throughDOM'] = recordBatchReaderThroughDOMStream;
-RecordBatchFileReader['throughDOM'] = recordBatchReaderThroughDOMStream;
-RecordBatchStreamReader['throughDOM'] = recordBatchReaderThroughDOMStream;
-RecordBatchWriter['throughDOM'] = recordBatchWriterThroughDOMStream;
-RecordBatchFileWriter['throughDOM'] = recordBatchWriterThroughDOMStream;
-RecordBatchStreamWriter['throughDOM'] = recordBatchWriterThroughDOMStream;
+// Override in IIFE so that bundlers don't tree-shake out this logic,
+// but also so we're still compliant with `"sideEffects": false`
+(() => {
+    streamAdapters.toDOMStream = toDOMStream;
+    Builder['throughDOM'] = builderThroughDOMStream;
+    RecordBatchReader['throughDOM'] = recordBatchReaderThroughDOMStream;
+    RecordBatchFileReader['throughDOM'] = recordBatchReaderThroughDOMStream;
+    RecordBatchStreamReader['throughDOM'] = recordBatchReaderThroughDOMStream;
+    RecordBatchWriter['throughDOM'] = recordBatchWriterThroughDOMStream;
+    RecordBatchFileWriter['throughDOM'] = recordBatchWriterThroughDOMStream;
+    RecordBatchStreamWriter['throughDOM'] = recordBatchWriterThroughDOMStream;
+})();
 
 export type {
     TypeMap, StructRowProxy,
diff --git a/js/src/Arrow.node.ts b/js/src/Arrow.node.ts
index d47f0880ff4..bedd88a6121 100644
--- a/js/src/Arrow.node.ts
+++ b/js/src/Arrow.node.ts
@@ -24,9 +24,13 @@ import { builderThroughNodeStream } from './io/node/builder.js';
 import { recordBatchReaderThroughNodeStream } from './io/node/reader.js';
 import { recordBatchWriterThroughNodeStream } from './io/node/writer.js';
 
-streamAdapters.toNodeStream = toNodeStream;
-Builder['throughNode'] = builderThroughNodeStream;
-RecordBatchReader['throughNode'] = recordBatchReaderThroughNodeStream;
-RecordBatchWriter['throughNode'] = recordBatchWriterThroughNodeStream;
+// Override in IIFE so that bundlers don't tree-shake out this logic,
+// but also so we're still compliant with `"sideEffects": false`
+(() => {
+    streamAdapters.toNodeStream = toNodeStream;
+    Builder['throughNode'] = builderThroughNodeStream;
+    RecordBatchReader['throughNode'] = recordBatchReaderThroughNodeStream;
+    RecordBatchWriter['throughNode'] = recordBatchWriterThroughNodeStream;
+})();
 
 export * from './Arrow.dom.js';