diff --git a/sdks/python/apache_beam/transforms/combiners.py b/sdks/python/apache_beam/transforms/combiners.py
index bcedd867386c..7e6b1f9d5b88 100644
--- a/sdks/python/apache_beam/transforms/combiners.py
+++ b/sdks/python/apache_beam/transforms/combiners.py
@@ -21,6 +21,7 @@
 
 import copy
 import heapq
+import itertools
 import operator
 import random
 from typing import Any
@@ -597,16 +598,24 @@ def teardown(self):
 
 
 class _TupleCombineFnBase(core.CombineFn):
-  def __init__(self, *combiners):
+  def __init__(self, *combiners, merge_accumulators_batch_size=None):
     self._combiners = [core.CombineFn.maybe_from_callable(c) for c in combiners]
     self._named_combiners = combiners
+    # If the `merge_accumulators_batch_size` value is not specified, we chose a
+    # bounded default that is inversely proportional to the number of
+    # accumulators in merged tuples.
+    self._merge_accumulators_batch_size = (
+        merge_accumulators_batch_size or max(10, 1000 // len(combiners)))
 
   def display_data(self):
     combiners = [
         c.__name__ if hasattr(c, '__name__') else c.__class__.__name__
         for c in self._named_combiners
     ]
-    return {'combiners': str(combiners)}
+    return {
+        'combiners': str(combiners),
+        'merge_accumulators_batch_size': self._merge_accumulators_batch_size
+    }
 
   def setup(self, *args, **kwargs):
     for c in self._combiners:
@@ -616,10 +625,23 @@ def create_accumulator(self, *args, **kwargs):
     return [c.create_accumulator(*args, **kwargs) for c in self._combiners]
 
   def merge_accumulators(self, accumulators, *args, **kwargs):
-    return [
-        c.merge_accumulators(a, *args, **kwargs) for c,
-        a in zip(self._combiners, zip(*accumulators))
-    ]
+    # Make sure that `accumulators` is an iterator (so that the position is
+    # remembered).
+    accumulators = iter(accumulators)
+    result = next(accumulators)
+    while True:
+      # Load accumulators into memory and merge in batches to decrease peak
+      # memory usage.
+      accumulators_batch = list(
+          itertools.islice(accumulators, self._merge_accumulators_batch_size))
+      if not accumulators_batch:
+        break
+      accumulators_batch += [result]
+      result = [
+          c.merge_accumulators(a, *args, **kwargs) for c,
+          a in zip(self._combiners, zip(*accumulators_batch))
+      ]
+    return result
 
   def compact(self, accumulator, *args, **kwargs):
     return [
diff --git a/sdks/python/apache_beam/transforms/combiners_test.py b/sdks/python/apache_beam/transforms/combiners_test.py
index d82628791ae4..68b273e930b2 100644
--- a/sdks/python/apache_beam/transforms/combiners_test.py
+++ b/sdks/python/apache_beam/transforms/combiners_test.py
@@ -249,7 +249,8 @@ def test_basic_combiners_display_data(self):
     dd = DisplayData.create_from(transform)
     expected_items = [
         DisplayDataItemMatcher('combine_fn', combine.TupleCombineFn),
-        DisplayDataItemMatcher('combiners', "['max', 'MeanCombineFn', 'sum']")
+        DisplayDataItemMatcher('combiners', "['max', 'MeanCombineFn', 'sum']"),
+        DisplayDataItemMatcher('merge_accumulators_batch_size', 333),
     ]
     hc.assert_that(dd.items, hc.contains_inanyorder(*expected_items))
 
@@ -358,6 +359,41 @@ def test_tuple_combine_fn_without_defaults(self):
                   max).with_common_input()).without_defaults())
       assert_that(result, equal_to([(1, 7.0 / 4, 3)]))
 
+  def test_tuple_combine_fn_batched_merge(self):
+    num_combine_fns = 10
+    max_num_accumulators_in_memory = 30
+    # Maximum number of accumulator tuples in memory - 1 for the merge result.
+    merge_accumulators_batch_size = (
+        max_num_accumulators_in_memory // num_combine_fns - 1)
+    num_accumulator_tuples_to_merge = 20
+
+    class CountedAccumulator:
+      count = 0
+      oom = False
+
+      def __init__(self):
+        if CountedAccumulator.count > max_num_accumulators_in_memory:
+          CountedAccumulator.oom = True
+        else:
+          CountedAccumulator.count += 1
+
+    class CountedAccumulatorCombineFn(beam.CombineFn):
+      def create_accumulator(self):
+        return CountedAccumulator()
+
+      def merge_accumulators(self, accumulators):
+        CountedAccumulator.count += 1
+        for _ in accumulators:
+          CountedAccumulator.count -= 1
+
+    combine_fn = combine.TupleCombineFn(
+        *[CountedAccumulatorCombineFn() for _ in range(num_combine_fns)],
+        merge_accumulators_batch_size=merge_accumulators_batch_size)
+    combine_fn.merge_accumulators(
+        combine_fn.create_accumulator()
+        for _ in range(num_accumulator_tuples_to_merge))
+    assert not CountedAccumulator.oom
+
   def test_to_list_and_to_dict1(self):
     with TestPipeline() as pipeline:
       the_list = [6, 3, 1, 1, 9, 1, 5, 2, 0, 6]