diff --git a/sdks/python/apache_beam/typehints/typehints.py b/sdks/python/apache_beam/typehints/typehints.py
index 487fb78d26bb..5cbb41e4d664 100644
--- a/sdks/python/apache_beam/typehints/typehints.py
+++ b/sdks/python/apache_beam/typehints/typehints.py
@@ -1190,6 +1190,13 @@ def normalize(x, none_as_type=False):
     return type(None)
   elif x in _KNOWN_PRIMITIVE_TYPES:
     return _KNOWN_PRIMITIVE_TYPES[x]
+  elif sys.version_info >= (3, 9) and isinstance(x, types.GenericAlias):
+    # TODO(https://github.com/apache/beam/issues/23366): handle PEP 585
+    # generic type hints properly
+    raise TypeError(
+        'PEP 585 generic type hints like %s are not yet supported, '
+        'use typing module containers instead. See equivalents listed '
+        'at https://docs.python.org/3/library/typing.html' % x)
   elif getattr(x, '__module__', None) == 'typing':
     # Avoid circular imports
     from apache_beam.typehints import native_type_compatibility
diff --git a/sdks/python/apache_beam/typehints/typehints_test.py b/sdks/python/apache_beam/typehints/typehints_test.py
index 532da8917f8c..7e2c390de320 100644
--- a/sdks/python/apache_beam/typehints/typehints_test.py
+++ b/sdks/python/apache_beam/typehints/typehints_test.py
@@ -523,6 +523,17 @@ def test_type_check_invalid_composite_type_arbitrary_length(self):
         "was received.",
         e.exception.args[0])
 
+  def test_normalize_with_builtin_tuple(self):
+    if sys.version_info >= (3, 9):
+      with self.assertRaises(TypeError) as e:
+        typehints.normalize(tuple[int, int], False)
+
+      self.assertEqual(
+          'PEP 585 generic type hints like tuple[int, int] are not yet '
+          'supported, use typing module containers instead. See equivalents '
+          'listed at https://docs.python.org/3/library/typing.html',
+          e.exception.args[0])
+
 
 class ListHintTestCase(TypeHintTestCase):
   def test_getitem_invalid_composite_type_param(self):
@@ -582,6 +593,17 @@ def test_enforce_list_type_constraint_invalid_composite_type(self):
         'instead received an instance of type str.',
         e.exception.args[0])
 
+  def test_normalize_with_builtin_list(self):
+    if sys.version_info >= (3, 9):
+      with self.assertRaises(TypeError) as e:
+        typehints.normalize(list[int], False)
+
+      self.assertEqual(
+          'PEP 585 generic type hints like list[int] are not yet supported, '
+          'use typing module containers instead. See equivalents listed '
+          'at https://docs.python.org/3/library/typing.html',
+          e.exception.args[0])
+
 
 class KVHintTestCase(TypeHintTestCase):
   def test_getitem_param_must_be_tuple(self):
@@ -717,6 +739,17 @@ def test_match_type_variables(self):
     },
                      hint.match_type_variables(typehints.Dict[int, str]))
 
+  def test_normalize_with_builtin_dict(self):
+    if sys.version_info >= (3, 9):
+      with self.assertRaises(TypeError) as e:
+        typehints.normalize(dict[int, str], False)
+
+      self.assertEqual(
+          'PEP 585 generic type hints like dict[int, str] are not yet '
+          'supported, use typing module containers instead. See equivalents '
+          'listed at https://docs.python.org/3/library/typing.html',
+          e.exception.args[0])
+
 
 class BaseSetHintTest:
   class CommonTests(TypeHintTestCase):