diff --git a/python/proton/_io.py b/python/proton/_io.py
index 482f327955..b4e4449bea 100644
--- a/python/proton/_io.py
+++ b/python/proton/_io.py
@@ -65,7 +65,7 @@ def connect(addr) -> socket.socket:
         try:
             s.connect(addr[4])
         except socket.error as e:
-            if e.errno not in (errno.EINPROGRESS, errno.EWOULDBLOCK, errno.EAGAIN):
+            if e.errno not in (errno.EINPROGRESS, errno.EWOULDBLOCK, errno.EAGAIN, errno.ENETUNREACH):
                 raise
         return s