diff --git a/apm-sniffer/apm-agent-core/src/main/java/org/apache/skywalking/apm/agent/core/conf/Config.java b/apm-sniffer/apm-agent-core/src/main/java/org/apache/skywalking/apm/agent/core/conf/Config.java
index 77847001aba0..1c12100b1fa1 100644
--- a/apm-sniffer/apm-agent-core/src/main/java/org/apache/skywalking/apm/agent/core/conf/Config.java
+++ b/apm-sniffer/apm-agent-core/src/main/java/org/apache/skywalking/apm/agent/core/conf/Config.java
@@ -194,6 +194,21 @@ public static class Toolkit {
             public static boolean USE_QUALIFIED_NAME_AS_OPERATION_NAME = false;
         }
 
+        public static class MySQL {
+            /**
+             * If set to true, the parameters of the sql (typically {@link java.sql.PreparedStatement})
+             * would be collected.
+             */
+            public static boolean TRACE_SQL_PARAMETERS = false;
+            /**
+             * For the sake of performance, SkyWalking won't save the entire parameters string into the tag,
+             * but only the first {@code SQL_PARAMETERS_MAX_LENGTH} characters.
+             *
+             * Set a negative number to save the complete parameter string to the tag.
+             */
+            public static int SQL_PARAMETERS_MAX_LENGTH = 512;
+        }
+
         public static class SolrJ {
             /**
              * If true, trace all the query parameters(include deleteByIds and deleteByQuery) in Solr query request, default is false.
diff --git a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementIgnorableSetterInterceptor.java b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementIgnorableSetterInterceptor.java
new file mode 100644
index 000000000000..9294ad67f5a3
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementIgnorableSetterInterceptor.java
@@ -0,0 +1,58 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+package org.apache.skywalking.apm.plugin.jdbc;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.EnhancedInstance;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.InstanceMethodsAroundInterceptor;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.MethodInterceptResult;
+import org.apache.skywalking.apm.plugin.jdbc.define.Constants;
+import org.apache.skywalking.apm.plugin.jdbc.define.StatementEnhanceInfos;
+
+import java.lang.reflect.Method;
+
+/**
+ * @author kezhenxu94
+ */
+public class JDBCPreparedStatementIgnorableSetterInterceptor implements InstanceMethodsAroundInterceptor {
+    @Override
+    public final void beforeMethod(EnhancedInstance objInst, Method method, Object[] allArguments,
+                                   Class<?>[] argumentsTypes,
+                                   MethodInterceptResult result) throws Throwable {
+        final StatementEnhanceInfos statementEnhanceInfos = (StatementEnhanceInfos) objInst.getSkyWalkingDynamicField();
+        final int index = (Integer) allArguments[0];
+        statementEnhanceInfos.setParameter(index, Constants.SQL_PARAMETER_PLACEHOLDER);
+    }
+
+    @Override
+    public final Object afterMethod(EnhancedInstance objInst,
+                                    Method method,
+                                    Object[] allArguments,
+                                    Class<?>[] argumentsTypes,
+                                    Object ret) throws Throwable {
+        return ret;
+    }
+
+    @Override
+    public final void handleMethodException(EnhancedInstance objInst,
+                                            Method method,
+                                            Object[] allArguments,
+                                            Class<?>[] argumentsTypes,
+                                            Throwable t) {
+    }
+}
diff --git a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint.java b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint.java
new file mode 100644
index 000000000000..04e619e39946
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint.java
@@ -0,0 +1,46 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+package org.apache.skywalking.apm.plugin.jdbc;
+
+import net.bytebuddy.description.method.MethodDescription;
+import net.bytebuddy.matcher.ElementMatcher;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.define.Constants;
+
+import static net.bytebuddy.matcher.ElementMatchers.named;
+
+/**
+ * @author kezhenxu94
+ */
+public final class JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint implements InstanceMethodsInterceptPoint {
+    @Override
+    public ElementMatcher<MethodDescription> getMethodsMatcher() {
+        return named("setNull");
+    }
+
+    @Override
+    public String getMethodsInterceptor() {
+        return Constants.PREPARED_STATEMENT_NULL_SETTER_METHODS_INTERCEPTOR;
+    }
+
+    @Override
+    public boolean isOverrideArgs() {
+        return false;
+    }
+}
diff --git a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementNullSetterInterceptor.java b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementNullSetterInterceptor.java
new file mode 100644
index 000000000000..fe721f63f75c
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementNullSetterInterceptor.java
@@ -0,0 +1,57 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+package org.apache.skywalking.apm.plugin.jdbc;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.EnhancedInstance;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.InstanceMethodsAroundInterceptor;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.MethodInterceptResult;
+import org.apache.skywalking.apm.plugin.jdbc.define.StatementEnhanceInfos;
+
+import java.lang.reflect.Method;
+
+/**
+ * @author kezhenxu94
+ */
+public class JDBCPreparedStatementNullSetterInterceptor implements InstanceMethodsAroundInterceptor {
+    @Override
+    public final void beforeMethod(EnhancedInstance objInst, Method method, Object[] allArguments,
+                                   Class<?>[] argumentsTypes,
+                                   MethodInterceptResult result) throws Throwable {
+        final StatementEnhanceInfos statementEnhanceInfos = (StatementEnhanceInfos) objInst.getSkyWalkingDynamicField();
+        final int index = (Integer) allArguments[0];
+        statementEnhanceInfos.setParameter(index, "NULL");
+    }
+
+    @Override
+    public final Object afterMethod(EnhancedInstance objInst,
+                                    Method method,
+                                    Object[] allArguments,
+                                    Class<?>[] argumentsTypes,
+                                    Object ret) throws Throwable {
+        return ret;
+    }
+
+    @Override
+    public final void handleMethodException(EnhancedInstance objInst,
+                                            Method method,
+                                            Object[] allArguments,
+                                            Class<?>[] argumentsTypes,
+                                            Throwable t) {
+    }
+}
diff --git a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementSetterInterceptor.java b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementSetterInterceptor.java
new file mode 100644
index 000000000000..2fce63283c71
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/JDBCPreparedStatementSetterInterceptor.java
@@ -0,0 +1,58 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+package org.apache.skywalking.apm.plugin.jdbc;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.EnhancedInstance;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.InstanceMethodsAroundInterceptor;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.enhance.MethodInterceptResult;
+import org.apache.skywalking.apm.plugin.jdbc.define.StatementEnhanceInfos;
+
+import java.lang.reflect.Method;
+
+/**
+ * @author kezhenxu94
+ */
+public class JDBCPreparedStatementSetterInterceptor implements InstanceMethodsAroundInterceptor {
+    @Override
+    public final void beforeMethod(EnhancedInstance objInst, Method method, Object[] allArguments,
+                                   Class<?>[] argumentsTypes,
+                                   MethodInterceptResult result) throws Throwable {
+        final StatementEnhanceInfos statementEnhanceInfos = (StatementEnhanceInfos) objInst.getSkyWalkingDynamicField();
+        final int index = (Integer) allArguments[0];
+        final Object parameter = allArguments[1];
+        statementEnhanceInfos.setParameter(index, parameter);
+    }
+
+    @Override
+    public final Object afterMethod(EnhancedInstance objInst,
+                                    Method method,
+                                    Object[] allArguments,
+                                    Class<?>[] argumentsTypes,
+                                    Object ret) throws Throwable {
+        return ret;
+    }
+
+    @Override
+    public final void handleMethodException(EnhancedInstance objInst,
+                                            Method method,
+                                            Object[] allArguments,
+                                            Class<?>[] argumentsTypes,
+                                            Throwable t) {
+    }
+}
diff --git a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/PSSetterDefinitionOfJDBCInstrumentation.java b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/PSSetterDefinitionOfJDBCInstrumentation.java
new file mode 100644
index 000000000000..fb7a4c060b07
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/PSSetterDefinitionOfJDBCInstrumentation.java
@@ -0,0 +1,69 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+package org.apache.skywalking.apm.plugin.jdbc;
+
+import net.bytebuddy.description.method.MethodDescription;
+import net.bytebuddy.matcher.ElementMatcher;
+import org.apache.skywalking.apm.agent.core.conf.Config;
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.define.Constants;
+
+import java.util.Set;
+
+import static net.bytebuddy.matcher.ElementMatchers.named;
+import static net.bytebuddy.matcher.ElementMatchers.none;
+import static org.apache.skywalking.apm.plugin.jdbc.define.Constants.PS_IGNORABLE_SETTERS;
+import static org.apache.skywalking.apm.plugin.jdbc.define.Constants.PS_SETTERS;
+
+/**
+ * @author kezhenxu94
+ */
+public class PSSetterDefinitionOfJDBCInstrumentation implements InstanceMethodsInterceptPoint {
+    private final boolean ignorable;
+
+    public PSSetterDefinitionOfJDBCInstrumentation(boolean ignorable) {
+        this.ignorable = ignorable;
+    }
+
+    @Override
+    public ElementMatcher<MethodDescription> getMethodsMatcher() {
+        ElementMatcher.Junction<MethodDescription> matcher = none();
+
+        if (Config.Plugin.MySQL.TRACE_SQL_PARAMETERS) {
+            final Set<String> setters = ignorable ? PS_IGNORABLE_SETTERS : PS_SETTERS;
+            for (String setter : setters) {
+                matcher = matcher.or(named(setter));
+            }
+        }
+
+        return matcher;
+    }
+
+    @Override
+    public String getMethodsInterceptor() {
+        return ignorable
+            ? Constants.PREPARED_STATEMENT_IGNORABLE_SETTER_METHODS_INTERCEPTOR
+            : Constants.PREPARED_STATEMENT_SETTER_METHODS_INTERCEPTOR;
+    }
+
+    @Override
+    public boolean isOverrideArgs() {
+        return false;
+    }
+}
diff --git a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/Constants.java b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/Constants.java
index 895a5cacae68..03902cf2e14c 100644
--- a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/Constants.java
+++ b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/Constants.java
@@ -19,6 +19,10 @@
 
 package org.apache.skywalking.apm.plugin.jdbc.define;
 
+import java.util.Arrays;
+import java.util.HashSet;
+import java.util.Set;
+
 public class Constants {
     public static final String CREATE_STATEMENT_INTERCEPT_CLASS = "org.apache.skywalking.apm.plugin.jdbc.JDBCStatementInterceptor";
 
@@ -41,5 +45,41 @@ public class Constants {
     public static final String CLOSE_METHOD_NAME = "close";
 
     public static final String RELEASE_SAVE_POINT_METHOD_NAME = "releaseSavepoint";
+    public static final String SQL_PARAMETER_PLACEHOLDER = "?";
+    public static final Set<String> PS_SETTERS = new HashSet<String>(Arrays.asList(
+        "setArray",
+        "setBigDecimal",
+        "setBoolean",
+        "setByte",
+        "setDate",
+        "setDouble",
+        "setFloat",
+        "setInt",
+        "setLong",
+        "setNString",
+        "setObject",
+        "setRowId",
+        "setShort",
+        "setString",
+        "setTime",
+        "setTimestamp",
+        "setURL"
+    ));
+    public static final Set<String> PS_IGNORABLE_SETTERS = new HashSet<String>(Arrays.asList(
+        "setAsciiStream",
+        "setBinaryStream",
+        "setBlob",
+        "setBytes",
+        "setCharacterStream",
+        "setClob",
+        "setNCharacterStream",
+        "setNClob",
+        "setRef",
+        "setSQLXML",
+        "setUnicodeStream"
+    ));
 
+    public static final String PREPARED_STATEMENT_SETTER_METHODS_INTERCEPTOR = "org.apache.skywalking.apm.plugin.jdbc.JDBCPreparedStatementSetterInterceptor";
+    public static final String PREPARED_STATEMENT_NULL_SETTER_METHODS_INTERCEPTOR = "org.apache.skywalking.apm.plugin.jdbc.JDBCPreparedStatementNullSetterInterceptor";
+    public static final String PREPARED_STATEMENT_IGNORABLE_SETTER_METHODS_INTERCEPTOR = "org.apache.skywalking.apm.plugin.jdbc.JDBCPreparedStatementIgnorableSetterInterceptor";
 }
diff --git a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/StatementEnhanceInfos.java b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/StatementEnhanceInfos.java
index c75a131b3658..3ec22a4692c2 100644
--- a/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/StatementEnhanceInfos.java
+++ b/apm-sniffer/apm-sdk-plugin/jdbc-commons/src/main/java/org/apache/skywalking/apm/plugin/jdbc/define/StatementEnhanceInfos.java
@@ -21,6 +21,8 @@
 
 import org.apache.skywalking.apm.plugin.jdbc.trace.ConnectionInfo;
 
+import java.util.Arrays;
+
 /**
  * {@link StatementEnhanceInfos} contain the {@link ConnectionInfo} and
  * <code>sql</code> for trace mysql.
@@ -31,6 +33,8 @@ public class StatementEnhanceInfos {
     private ConnectionInfo connectionInfo;
     private String statementName;
     private String sql;
+    private Object[] parameters;
+    private int maxIndex = 0;
 
     public StatementEnhanceInfos(ConnectionInfo connectionInfo, String sql, String statementName) {
         this.connectionInfo = connectionInfo;
@@ -49,4 +53,31 @@ public String getSql() {
     public String getStatementName() {
         return statementName;
     }
+
+    public void setParameter(int index, final Object parameter) {
+        maxIndex = maxIndex > index ? maxIndex : index;
+        index--; // start from 1
+        if (parameters == null) {
+            final int initialSize = Math.max(20, maxIndex);
+            parameters = new Object[initialSize];
+            Arrays.fill(parameters, null);
+        }
+        int length = parameters.length;
+        if (index >= length) {
+            int newSize = Math.max(index + 1, length * 2);
+            Object[] newParameters = new Object[newSize];
+            System.arraycopy(parameters, 0, newParameters, 0, length);
+            Arrays.fill(newParameters, length, newSize, null);
+            parameters = newParameters;
+        }
+        parameters[index] = parameter;
+    }
+
+    public Object[] getParameters() {
+        return parameters;
+    }
+
+    public int getMaxIndex() {
+        return maxIndex;
+    }
 }
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementIgnoredSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementIgnoredSetterInstrumentation.java
new file mode 100644
index 000000000000..99f1c648b822
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementIgnoredSetterInstrumentation.java
@@ -0,0 +1,35 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.PSSetterDefinitionOfJDBCInstrumentation;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementIgnoredSetterInstrumentation extends PreparedStatementInstrumentation {
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new PSSetterDefinitionOfJDBCInstrumentation(true)
+        };
+    }
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementInstrumentation.java
index 77670ea053ea..0837b46ec86f 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementInstrumentation.java
+++ b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementInstrumentation.java
@@ -31,13 +31,13 @@
 
 /**
  * {@link PreparedStatementInstrumentation} define that the mysql-2.x plugin intercepts the following methods in the
- * com.mysql.jdbc.JDBC42PreparedStatement, com.mysql.jdbc.PreparedStatement and 
+ * com.mysql.jdbc.JDBC42PreparedStatement, com.mysql.jdbc.PreparedStatement and
  * com.mysql.cj.jdbc.PreparedStatement class:
- * 1. execute 
- * 2. executeQuery 
- * 3. executeUpdate 
- * 4. executeLargeUpdate 
- * 5. addBatch 
+ * 1. execute
+ * 2. executeQuery
+ * 3. executeUpdate
+ * 4. executeLargeUpdate
+ * 5. addBatch
  *
  * @author zhangxin
  */
@@ -51,7 +51,7 @@ public class PreparedStatementInstrumentation extends AbstractMysqlInstrumentati
         return new ConstructorInterceptPoint[0];
     }
 
-    @Override protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+    @Override protected InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
         return new InstanceMethodsInterceptPoint[] {
             new InstanceMethodsInterceptPoint() {
                 @Override public ElementMatcher<MethodDescription> getMethodsMatcher() {
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementNullSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementNullSetterInstrumentation.java
new file mode 100644
index 000000000000..8e078b9b5c42
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementNullSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementNullSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint()
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementSetterInstrumentation.java
new file mode 100644
index 000000000000..9acddbc48654
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v5/define/PreparedStatementSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.PSSetterDefinitionOfJDBCInstrumentation;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new PSSetterDefinitionOfJDBCInstrumentation(false)
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/resources/skywalking-plugin.def b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/resources/skywalking-plugin.def
index a8350c951ad3..57fea2cc38b0 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/resources/skywalking-plugin.def
+++ b/apm-sniffer/apm-sdk-plugin/mysql-5.x-plugin/src/main/resources/skywalking-plugin.def
@@ -21,3 +21,6 @@ mysql-5.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define.PreparedStatemen
 mysql-5.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define.StatementInstrumentation
 mysql-5.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define.CacheIpsInstrumentation
 mysql-5.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define.ConnectionImplCreateInstrumentation
+mysql-5.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define.PreparedStatementIgnoredSetterInstrumentation
+mysql-5.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define.PreparedStatementSetterInstrumentation
+mysql-5.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v5.define.PreparedStatementNullSetterInstrumentation
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementIgnoredSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementIgnoredSetterInstrumentation.java
new file mode 100644
index 000000000000..ea7d598d0257
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementIgnoredSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.PSSetterDefinitionOfJDBCInstrumentation;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementIgnoredSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new PSSetterDefinitionOfJDBCInstrumentation(true)
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementInstrumentation.java
index 89feca9332e7..958c4145fca3 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementInstrumentation.java
+++ b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementInstrumentation.java
@@ -30,13 +30,13 @@
 
 /**
  * {@link PreparedStatementInstrumentation} define that the mysql-2.x plugin intercepts the following methods in the
- * com.mysql.jdbc.JDBC42PreparedStatement, com.mysql.jdbc.PreparedStatement and 
+ * com.mysql.jdbc.JDBC42PreparedStatement, com.mysql.jdbc.PreparedStatement and
  * com.mysql.cj.jdbc.PreparedStatement class:
- * 1. execute 
- * 2. executeQuery 
- * 3. executeUpdate 
- * 4. executeLargeUpdate 
- * 5. addBatch 
+ * 1. execute
+ * 2. executeQuery
+ * 3. executeUpdate
+ * 4. executeLargeUpdate
+ * 5. addBatch
  *
  * @author zhangxin
  */
@@ -49,7 +49,7 @@ public class PreparedStatementInstrumentation extends AbstractMysqlInstrumentati
         return new ConstructorInterceptPoint[0];
     }
 
-    @Override protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+    @Override protected InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
         return new InstanceMethodsInterceptPoint[] {
             new InstanceMethodsInterceptPoint() {
                 @Override public ElementMatcher<MethodDescription> getMethodsMatcher() {
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementNullSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementNullSetterInstrumentation.java
new file mode 100644
index 000000000000..023867460972
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementNullSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementNullSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint()
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementSetterInstrumentation.java
new file mode 100644
index 000000000000..24778ca8bf33
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v6/define/PreparedStatementSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.PSSetterDefinitionOfJDBCInstrumentation;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new PSSetterDefinitionOfJDBCInstrumentation(false)
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/resources/skywalking-plugin.def b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/resources/skywalking-plugin.def
index 087d2af2bf81..c5af17ea9cec 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/resources/skywalking-plugin.def
+++ b/apm-sniffer/apm-sdk-plugin/mysql-6.x-plugin/src/main/resources/skywalking-plugin.def
@@ -21,3 +21,6 @@ mysql-6.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define.PreparedStatemen
 mysql-6.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define.StatementInstrumentation
 mysql-6.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define.CacheIpsInstrumentation
 mysql-6.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define.ConnectionImplCreateInstrumentation
+mysql-6.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define.PreparedStatementSetterInstrumentation
+mysql-6.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define.PreparedStatementIgnoredSetterInstrumentation
+mysql-6.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v6.define.PreparedStatementNullSetterInstrumentation
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementIgnoredSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementIgnoredSetterInstrumentation.java
new file mode 100644
index 000000000000..40dff470b596
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementIgnoredSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.PSSetterDefinitionOfJDBCInstrumentation;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementIgnoredSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new PSSetterDefinitionOfJDBCInstrumentation(true)
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementInstrumentation.java
index 183c45d290e8..180b0a009c7f 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementInstrumentation.java
+++ b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementInstrumentation.java
@@ -40,7 +40,7 @@ public class PreparedStatementInstrumentation extends AbstractMysqlInstrumentati
         return new ConstructorInterceptPoint[0];
     }
 
-    @Override protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+    @Override protected InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
         return new InstanceMethodsInterceptPoint[] {
             new InstanceMethodsInterceptPoint() {
                 @Override public ElementMatcher<MethodDescription> getMethodsMatcher() {
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementNullSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementNullSetterInstrumentation.java
new file mode 100644
index 000000000000..8f47621dafbd
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementNullSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementNullSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new JDBCPreparedStatementNullSetterInstanceMethodsInterceptPoint()
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementSetterInstrumentation.java b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementSetterInstrumentation.java
new file mode 100644
index 000000000000..12789f250e33
--- /dev/null
+++ b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/v8/define/PreparedStatementSetterInstrumentation.java
@@ -0,0 +1,37 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+
+package org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define;
+
+import org.apache.skywalking.apm.agent.core.plugin.interceptor.InstanceMethodsInterceptPoint;
+import org.apache.skywalking.apm.plugin.jdbc.PSSetterDefinitionOfJDBCInstrumentation;
+
+/**
+ * @author kezhenxu94
+ */
+public class PreparedStatementSetterInstrumentation extends PreparedStatementInstrumentation {
+
+    @Override
+    protected final InstanceMethodsInterceptPoint[] getInstanceMethodsInterceptPoints() {
+        return new InstanceMethodsInterceptPoint[] {
+            new PSSetterDefinitionOfJDBCInstrumentation(false)
+        };
+    }
+
+}
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/resources/skywalking-plugin.def b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/resources/skywalking-plugin.def
index 5a3c552fce31..11db6da6e97a 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/resources/skywalking-plugin.def
+++ b/apm-sniffer/apm-sdk-plugin/mysql-8.x-plugin/src/main/resources/skywalking-plugin.def
@@ -19,3 +19,6 @@ mysql-8.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define.ConnectionInstru
 mysql-8.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define.CallableInstrumentation
 mysql-8.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define.PreparedStatementInstrumentation
 mysql-8.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define.StatementInstrumentation
+mysql-8.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define.PreparedStatementSetterInstrumentation
+mysql-8.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define.PreparedStatementNullSetterInstrumentation
+mysql-8.x=org.apache.skywalking.apm.plugin.jdbc.mysql.v8.define.PreparedStatementIgnoredSetterInstrumentation
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/Constants.java b/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/Constants.java
index a22c79b32e58..80dcb147c526 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/Constants.java
+++ b/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/Constants.java
@@ -18,6 +18,8 @@
 
 package org.apache.skywalking.apm.plugin.jdbc.mysql;
 
+import org.apache.skywalking.apm.agent.core.context.tag.StringTag;
+
 /**
  * @author: dingshaocheng
  */
@@ -29,4 +31,6 @@ public class Constants {
     public static final String SET_CATALOG_INTERCEPTOR = "org.apache.skywalking.apm.plugin.jdbc.mysql.SetCatalogInterceptor";
     public static final String STATEMENT_EXECUTE_METHODS_INTERCEPTOR = "org.apache.skywalking.apm.plugin.jdbc.mysql.StatementExecuteMethodsInterceptor";
     public static final String DRIVER_CONNECT_INTERCEPTOR = "org.apache.skywalking.apm.plugin.jdbc.mysql.DriverConnectInterceptor";
+
+    public static final StringTag SQL_PARAMETERS = new StringTag("db.sql.parameters");
 }
diff --git a/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/PreparedStatementExecuteMethodsInterceptor.java b/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/PreparedStatementExecuteMethodsInterceptor.java
index 5af6e98831f4..732816c07d08 100644
--- a/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/PreparedStatementExecuteMethodsInterceptor.java
+++ b/apm-sniffer/apm-sdk-plugin/mysql-common/src/main/java/org/apache/skywalking/apm/plugin/jdbc/mysql/PreparedStatementExecuteMethodsInterceptor.java
@@ -18,6 +18,7 @@
 
 package org.apache.skywalking.apm.plugin.jdbc.mysql;
 
+import org.apache.skywalking.apm.agent.core.conf.Config;
 import org.apache.skywalking.apm.agent.core.context.ContextManager;
 import org.apache.skywalking.apm.agent.core.context.tag.Tags;
 import org.apache.skywalking.apm.agent.core.context.trace.AbstractSpan;
@@ -30,6 +31,8 @@
 
 import java.lang.reflect.Method;
 
+import static org.apache.skywalking.apm.plugin.jdbc.mysql.Constants.SQL_PARAMETERS;
+
 public class PreparedStatementExecuteMethodsInterceptor implements InstanceMethodsAroundInterceptor {
 
     @Override
@@ -52,6 +55,19 @@ public final void beforeMethod(EnhancedInstance objInst, Method method, Object[]
             Tags.DB_STATEMENT.set(span, cacheObject.getSql());
             span.setComponent(connectInfo.getComponent());
 
+            if (Config.Plugin.MySQL.TRACE_SQL_PARAMETERS) {
+                final Object[] parameters = cacheObject.getParameters();
+                if (parameters != null && parameters.length > 0) {
+                    int maxIndex = cacheObject.getMaxIndex();
+                    String parameterString = buildParameterString(parameters, maxIndex);
+                    int sqlParametersMaxLength = Config.Plugin.MySQL.SQL_PARAMETERS_MAX_LENGTH;
+                    if (sqlParametersMaxLength > 0 && parameterString.length() > sqlParametersMaxLength) {
+                        parameterString = parameterString.substring(0, sqlParametersMaxLength) + "...";
+                    }
+                    SQL_PARAMETERS.set(span, parameterString);
+                }
+            }
+
             SpanLayer.asDB(span);
         }
     }
@@ -78,4 +94,19 @@ public final Object afterMethod(EnhancedInstance objInst, Method method, Object[
     private String buildOperationName(ConnectionInfo connectionInfo, String methodName, String statementName) {
         return connectionInfo.getDBType() + "/JDBI/" + statementName + "/" + methodName;
     }
+
+    private String buildParameterString(Object[] parameters, int maxIndex) {
+        String parameterString = "[";
+        boolean first = true;
+        for (int i = 0; i < maxIndex; i++) {
+            Object parameter = parameters[i];
+            if (!first) {
+                parameterString += ",";
+            }
+            parameterString += parameter;
+            first = false;
+        }
+        parameterString += "]";
+        return parameterString;
+    }
 }
diff --git a/apm-sniffer/apm-test-tools/src/test/java/org/apache/skywalking/apm/plugin/ArbitrarySetTest.java b/apm-sniffer/apm-test-tools/src/test/java/org/apache/skywalking/apm/plugin/ArbitrarySetTest.java
new file mode 100644
index 000000000000..36a585a2ae18
--- /dev/null
+++ b/apm-sniffer/apm-test-tools/src/test/java/org/apache/skywalking/apm/plugin/ArbitrarySetTest.java
@@ -0,0 +1,118 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *     http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ *
+ */
+
+package org.apache.skywalking.apm.plugin;
+
+import org.openjdk.jmh.annotations.Benchmark;
+import org.openjdk.jmh.annotations.BenchmarkMode;
+import org.openjdk.jmh.annotations.Fork;
+import org.openjdk.jmh.annotations.Measurement;
+import org.openjdk.jmh.annotations.Mode;
+import org.openjdk.jmh.annotations.OutputTimeUnit;
+import org.openjdk.jmh.annotations.Scope;
+import org.openjdk.jmh.annotations.State;
+import org.openjdk.jmh.annotations.Warmup;
+import org.openjdk.jmh.runner.Runner;
+import org.openjdk.jmh.runner.RunnerException;
+import org.openjdk.jmh.runner.options.Options;
+import org.openjdk.jmh.runner.options.OptionsBuilder;
+
+import java.util.ArrayList;
+import java.util.Arrays;
+import java.util.Collections;
+import java.util.LinkedList;
+import java.util.Map;
+import java.util.TreeMap;
+import java.util.concurrent.TimeUnit;
+
+/**
+ * Benchmark                     Mode  Cnt     Score     Error   Units
+ * ArbitrarySetTest.array       thrpt   10  2360.500 ± 138.279  ops/ms
+ * ArbitrarySetTest.arrayList   thrpt   10  1080.005 ± 225.897  ops/ms
+ * ArbitrarySetTest.linkedList  thrpt   10   188.007 ±  11.739  ops/ms
+ * ArbitrarySetTest.treeMap     thrpt   10   214.384 ±  27.816  ops/ms
+ *
+ * @author kezhenxu94
+ */
+@BenchmarkMode(Mode.Throughput)
+@OutputTimeUnit(TimeUnit.MILLISECONDS)
+@State(Scope.Thread)
+@Fork(2)
+@Warmup(iterations = 4)
+@Measurement(iterations = 5)
+public class ArbitrarySetTest {
+    private static final Object PLACEHOLDER = new Object();
+
+    @Benchmark
+    public void arrayList() {
+        ArrayList<Object> list = new ArrayList<Object>(Collections.nCopies(20, PLACEHOLDER));
+        for (int i = 0; i < 100; i++) {
+            int oldSize = list.size();
+            if (i >= oldSize) {
+                int newSize = Math.max(oldSize * 2, i);
+                list.addAll(oldSize, Collections.nCopies(newSize - oldSize, PLACEHOLDER));
+            }
+            list.set(i, i);
+        }
+    }
+
+    @Benchmark
+    public void linkedList() {
+        LinkedList<Object> list = new LinkedList<Object>(Collections.nCopies(20, PLACEHOLDER));
+        for (int i = 0; i < 100; i++) {
+            int oldSize = list.size();
+            if (i >= oldSize) {
+                int newSize = Math.max(oldSize * 2, i);
+                list.addAll(oldSize, Collections.nCopies(newSize - oldSize, PLACEHOLDER));
+            }
+            list.set(i, i);
+        }
+    }
+
+    @Benchmark
+    public void array() {
+        Object[] array = new Object[20];
+        Arrays.fill(array, PLACEHOLDER);
+        for (int i = 1; i <= 100; i++) {
+            int length = array.length;
+            if (i >= length) {
+                int newSize = Math.max(i, length * 2);
+                Object[] newArray = new Object[newSize];
+                System.arraycopy(array, 0, newArray, 0, length);
+                Arrays.fill(newArray, length, newSize, PLACEHOLDER);
+                array = newArray;
+            }
+            array[i] = i;
+        }
+    }
+
+    @Benchmark
+    public void treeMap() {
+        final Map<Integer, Object> treeMap = new TreeMap<Integer, Object>();
+        for (int i = 0; i < 100; i++) {
+            treeMap.put(i, i);
+        }
+    }
+
+    @BenchmarkMode(Mode.AverageTime)
+    @OutputTimeUnit(TimeUnit.MICROSECONDS)
+    public static void main(String[] args) throws RunnerException {
+        Options options = new OptionsBuilder().include(ArbitrarySetTest.class.getSimpleName()).build();
+        new Runner(options).run();
+    }
+}
diff --git a/docs/en/setup/service-agent/java-agent/README.md b/docs/en/setup/service-agent/java-agent/README.md
index 9b727d5d2a24..2d18851c3cf0 100644
--- a/docs/en/setup/service-agent/java-agent/README.md
+++ b/docs/en/setup/service-agent/java-agent/README.md
@@ -82,11 +82,13 @@ property key | Description | Default |
 `plugin.elasticsearch.trace_dsl`|If true, trace all the DSL(Domain Specific Language) in ElasticSearch access, default is false.|`false`|
 `plugin.springmvc.use_qualified_name_as_endpoint_name`|If true, the fully qualified method name will be used as the endpoint name instead of the request URL, default is false.|`false`|
 `plugin.toolit.use_qualified_name_as_operation_name`|If true, the fully qualified method name will be used as the operation name instead of the given operation name, default is false.|`false`|
+`plugin.mysql.trace_sql_parameters`|If set to true, the parameters of the sql (typically `java.sql.PreparedStatement`) would be collected.|`false`|
+`plugin.mysql.sql_parameters_max_length`|If set to positive number, the `db.sql.parameters` would be truncated to this length, otherwise it would be completely saved, which may cause performance problem.|`512`|
 `plugin.solrj.trace_statement`|If true, trace all the query parameters(include deleteByIds and deleteByQuery) in Solr query request, default is false.|`false`|
 `plugin.solrj.trace_ops_params`|If true, trace all the operation parameters in Solr request, default is false.|`false`|
 
 ## Optional Plugins
-Java agent plugins are all pluggable. Optional plugins could be provided in `optional-plugins` folder under agent or 3rd party repositores.
+Java agent plugins are all pluggable. Optional plugins could be provided in `optional-plugins` folder under agent or 3rd party repositories.
 For using these plugins, you need to put the target plugin jar file into `/plugins`.
 
 Now, we have the following known optional plugins.