diff --git a/iocore/net/quic/QUICBidirectionalStream.cc b/iocore/net/quic/QUICBidirectionalStream.cc
index 9565b0ac444..936b5fbbc85 100644
--- a/iocore/net/quic/QUICBidirectionalStream.cc
+++ b/iocore/net/quic/QUICBidirectionalStream.cc
@@ -355,8 +355,16 @@ bool
 QUICBidirectionalStream::will_generate_frame(QUICEncryptionLevel level, size_t current_packet_size, bool ack_eliciting,
                                              uint32_t seq_num)
 {
-  return this->_local_flow_controller.will_generate_frame(level, current_packet_size, ack_eliciting, seq_num) ||
-         !this->is_retransmited_frame_queue_empty() || this->_write_vio.get_reader()->is_read_avail_more_than(0);
+  if (this->_local_flow_controller.will_generate_frame(level, current_packet_size, ack_eliciting, seq_num)) {
+    return true;
+  }
+  if (!this->is_retransmited_frame_queue_empty()) {
+    return true;
+  }
+  if (this->_write_vio.op != VIO::NONE && this->_write_vio.get_reader()->is_read_avail_more_than(0)) {
+    return true;
+  };
+  return false;
 }
 
 QUICFrame *
diff --git a/iocore/net/quic/QUICUnidirectionalStream.cc b/iocore/net/quic/QUICUnidirectionalStream.cc
index 9a2d32143e0..73846221b6f 100644
--- a/iocore/net/quic/QUICUnidirectionalStream.cc
+++ b/iocore/net/quic/QUICUnidirectionalStream.cc
@@ -127,7 +127,13 @@ QUICSendStream::state_stream_closed(int event, void *data)
 bool
 QUICSendStream::will_generate_frame(QUICEncryptionLevel level, size_t current_packet_size, bool ack_eliciting, uint32_t seq_num)
 {
-  return !this->is_retransmited_frame_queue_empty() || this->_write_vio.get_reader()->is_read_avail_more_than(0);
+  if (!this->is_retransmited_frame_queue_empty()) {
+    return true;
+  }
+  if (this->_write_vio.op != VIO::NONE && this->_write_vio.get_reader()->is_read_avail_more_than(0)) {
+    return true;
+  }
+  return false;
 }
 
 QUICFrame *
@@ -529,8 +535,13 @@ QUICReceiveStream::is_cancelled() const
 bool
 QUICReceiveStream::will_generate_frame(QUICEncryptionLevel level, size_t current_packet_size, bool ack_eliciting, uint32_t seq_num)
 {
-  return this->_local_flow_controller.will_generate_frame(level, current_packet_size, ack_eliciting, seq_num) ||
-         (this->_stop_sending_reason != nullptr && this->_is_stop_sending_sent == false);
+  if (this->_local_flow_controller.will_generate_frame(level, current_packet_size, ack_eliciting, seq_num)) {
+    return true;
+  }
+  if (this->_stop_sending_reason != nullptr && this->_is_stop_sending_sent == false) {
+    return true;
+  }
+  return false;
 }
 
 QUICFrame *
diff --git a/iocore/net/quic/test/test_QUICStream.cc b/iocore/net/quic/test/test_QUICStream.cc
index 3d57a81ba06..8a7d2ee98bc 100644
--- a/iocore/net/quic/test/test_QUICStream.cc
+++ b/iocore/net/quic/test/test_QUICStream.cc
@@ -836,3 +836,22 @@ TEST_CASE("QUIC send only stream", "[quic]")
     CHECK(frame->type() == QUICFrameType::RESET_STREAM);
   }
 }
+
+TEST_CASE("will_generate_frame", "[quic]")
+{
+  SECTION("Return false if a stream has not initialized for IO")
+  {
+    QUICRTTMeasure rtt_provider;
+    MockQUICConnectionInfoProvider cinfo_provider;
+
+    std::unique_ptr<QUICBidirectionalStream> stream_bidi(
+      new QUICBidirectionalStream(&rtt_provider, &cinfo_provider, 0, 1024, 1024));
+    CHECK(stream_bidi->will_generate_frame(QUICEncryptionLevel::ONE_RTT, 0, false, 0) == false);
+
+    std::unique_ptr<QUICSendStream> stream_uni1(new QUICSendStream(&cinfo_provider, 2, 1024));
+    CHECK(stream_uni1->will_generate_frame(QUICEncryptionLevel::ONE_RTT, 0, false, 0) == false);
+
+    std::unique_ptr<QUICReceiveStream> stream_uni2(new QUICReceiveStream(&rtt_provider, &cinfo_provider, 3, 1024));
+    CHECK(stream_uni2->will_generate_frame(QUICEncryptionLevel::ONE_RTT, 0, false, 0) == false);
+  }
+}