diff --git a/apps/bundle_deploy/Makefile b/apps/bundle_deploy/Makefile
index f0e0c0fa05bc..b81df55852fa 100644
--- a/apps/bundle_deploy/Makefile
+++ b/apps/bundle_deploy/Makefile
@@ -64,8 +64,6 @@ $(else)
 QUIET ?= @
 $(endif)
 
-CRT_SRCS = $(shell find $(CRT_ROOT))
-
 MODEL_OBJ = $(build_dir)/model_c/devc.o $(build_dir)/model_c/lib0.o $(build_dir)/model_c/lib1.o
 TEST_MODEL_OBJ = $(build_dir)/test_model_c/devc.o $(build_dir)/test_model_c/lib0.o $(build_dir)/test_model_c/lib1.o
 
@@ -83,14 +81,20 @@ demo_static: $(build_dir)/demo_static $(build_dir)/cat.bin
 test_static: $(build_dir)/test_static $(build_dir)/test_data_c.bin $(build_dir)/test_output_c.bin
 	$(QUIET)TVM_NUM_THREADS=1 $(build_dir)/test_static $(build_dir)/test_data_c.bin $(build_dir)/test_output_c.bin $(build_dir)/test_graph_c.json $(build_dir)/test_params_c.bin
 
-$(build_dir)/crt/libcommon.a: $(CRT_SRCS)
-	$(QUIET)cd $(CRT_ROOT) && make QUIET= BUILD_DIR=$(abspath $(build_dir))/crt CRT_CONFIG=$(abspath $(build_dir)/crt_config/crt_config.h) "EXTRA_CFLAGS=$(PKG_COMPILE_OPTS)" common
+$(build_dir)/crt_config/crt_config.h:
+	$(QUIET)mkdir --parents $(build_dir)/crt_config && cp ../../build/microtvm_template_projects/crt/crt_config/crt_config.h $(build_dir)/crt_config/crt_config.h
+
+$(build_dir)/crt:
+	$(QUIET)mkdir --parents $(build_dir)/crt && cp -r $(CRT_ROOT)/* $(build_dir)/crt
+
+$(build_dir)/libcommon.a: $(build_dir)/crt $(build_dir)/crt_config/crt_config.h
+	$(QUIET)cd $(build_dir)/crt && mkdir -p build && cd build && cmake -DCRT_CONFIG_PATH=$(abspath $(build_dir)/crt_config) -DCMAKE_C_FLAGS="${PKG_COMPILE_OPTS}" .. && make && cp libcommon.a $(abspath $(build_dir)/libcommon.a)
 
-$(build_dir)/crt/libgraph_executor.a: $(CRT_SRCS)
-	$(QUIET)cd $(CRT_ROOT) && make QUIET= BUILD_DIR=$(abspath $(build_dir))/crt CRT_CONFIG=$(abspath $(build_dir)/crt_config/crt_config.h) "EXTRA_CFLAGS=$(PKG_COMPILE_OPTS)" graph_executor
+$(build_dir)/libgraph_executor.a: $(build_dir)/crt $(build_dir)/crt_config/crt_config.h
+	$(QUIET)cd $(build_dir)/crt && mkdir -p build && cd build && cmake -DCRT_CONFIG_PATH=$(abspath $(build_dir)/crt_config) -DCMAKE_C_FLAGS="${PKG_COMPILE_OPTS}" .. && make && cp libgraph_executor.a $(abspath $(build_dir)/libgraph_executor.a)
 
-$(build_dir)/crt/libmemory.a: $(CRT_SRCS)
-	$(QUIET)cd $(CRT_ROOT) && make QUIET= BUILD_DIR=$(abspath $(build_dir))/crt CRT_CONFIG=$(abspath $(build_dir)/crt_config/crt_config.h) "EXTRA_CFLAGS=$(PKG_COMPILE_OPTS)" memory
+$(build_dir)/libmemory.a: $(build_dir)/crt $(build_dir)/crt_config/crt_config.h
+	$(QUIET)cd $(build_dir)/crt && mkdir -p build && cd build && cmake -DCRT_CONFIG_PATH=$(abspath $(build_dir)/crt_config) -DCMAKE_C_FLAGS="${PKG_COMPILE_OPTS}" .. && make && cp libmemory.a $(abspath $(build_dir)/libmemory.a)
 
 $(build_dir)/demo_dynamic: demo.cc
 	$(QUIET)mkdir -p $(@D)
@@ -100,11 +104,11 @@ $(build_dir)/test_dynamic: test.cc ${build_dir}/test_graph_c.json ${build_dir}/t
 	$(QUIET)mkdir -p $(@D)
 	$(QUIET)g++ $(PKG_CXXFLAGS) -o $@ test.cc $(BACKTRACE_OBJS) $(BACKTRACE_LDFLAGS)
 
-$(build_dir)/demo_static: demo_static.c ${build_dir}/bundle_static.o $(MODEL_OBJ) ${build_dir}/crt/libmemory.a ${build_dir}/crt/libgraph_executor.a ${build_dir}/crt/libcommon.a ${build_dir}/graph_c.json.c ${build_dir}/params_c.bin.c $(BACKTRACE_OBJS)
+$(build_dir)/demo_static: demo_static.c ${build_dir}/bundle_static.o $(MODEL_OBJ) ${build_dir}/libmemory.a ${build_dir}/libgraph_executor.a ${build_dir}/libcommon.a ${build_dir}/graph_c.json.c ${build_dir}/params_c.bin.c $(BACKTRACE_OBJS)
 	$(QUIET)mkdir -p $(@D)
 	$(QUIET)gcc $(PKG_CFLAGS) -o $@ $^ $(PKG_LDFLAGS) $(BACKTRACE_LDFLAGS) $(BACKTRACE_CFLAGS)
 
-$(build_dir)/test_static: test_static.c ${build_dir}/bundle_static.o $(TEST_MODEL_OBJ) ${build_dir}/crt/libmemory.a ${build_dir}/crt/libgraph_executor.a ${build_dir}/crt/libcommon.a $(BACKTRACE_OBJS)
+$(build_dir)/test_static: test_static.c ${build_dir}/bundle_static.o $(TEST_MODEL_OBJ) ${build_dir}/libmemory.a ${build_dir}/libgraph_executor.a ${build_dir}/libcommon.a $(BACKTRACE_OBJS)
 	$(QUIET)mkdir -p $(@D)
 	$(QUIET)gcc $(PKG_CFLAGS) -o $@ $^ $(BACKTRACE_LDFLAGS)
 
@@ -142,7 +146,7 @@ $(build_dir)/bundle.so: bundle.cc runtime.cc $(build_dir)/model_cpp.o
 	$(QUIET)mkdir -p $(@D)
 	$(QUIET)g++ -shared $(PKG_CXXFLAGS) -fvisibility=hidden -o $@  $^ $(PKG_LDFLAGS)
 
-$(build_dir)/bundle_c.so: bundle.c $(MODEL_OBJ) ${build_dir}/crt/libmemory.a ${build_dir}/crt/libgraph_executor.a ${build_dir}/crt/libcommon.a $(BACKTRACE_OBJS)
+$(build_dir)/bundle_c.so: bundle.c $(MODEL_OBJ) ${build_dir}/libmemory.a ${build_dir}/libgraph_executor.a ${build_dir}/libcommon.a $(BACKTRACE_OBJS)
 	$(QUIET)mkdir -p $(@D)
 	$(QUIET)gcc -shared $(PKG_CFLAGS) -fvisibility=hidden -o $@  $^ $(PKG_LDFLAGS) $(BACKTRACE_LDFLAGS) $(BACKTRACE_CFLAGS)
 
@@ -150,7 +154,7 @@ $(build_dir)/test_bundle.so: bundle.cc runtime.cc $(build_dir)/test_model_cpp.o
 	$(QUIET)mkdir -p $(@D)
 	$(QUIET)g++ -shared $(PKG_CXXFLAGS) -fvisibility=hidden -o $@  $^ $(PKG_LDFLAGS)
 
-$(build_dir)/test_bundle_c.so: bundle.c $(TEST_MODEL_OBJ) ${build_dir}/crt/libmemory.a ${build_dir}/crt/libgraph_executor.a ${build_dir}/crt/libcommon.a $(BACKTRACE_OBJS)
+$(build_dir)/test_bundle_c.so: bundle.c $(TEST_MODEL_OBJ) ${build_dir}/libmemory.a ${build_dir}/libgraph_executor.a ${build_dir}/libcommon.a $(BACKTRACE_OBJS)
 	$(QUIET)mkdir -p $(@D)
 	$(QUIET)gcc -shared $(PKG_CFLAGS) -fvisibility=hidden -o $@  $^ $(PKG_LDFLAGS) $(BACKTRACE_LDFLAGS) $(BACKTRACE_CFLAGS)
 
diff --git a/apps/bundle_deploy/build_model.py b/apps/bundle_deploy/build_model.py
index 621846611d80..2f8feeba633b 100644
--- a/apps/bundle_deploy/build_model.py
+++ b/apps/bundle_deploy/build_model.py
@@ -26,7 +26,6 @@
 import logging
 from tvm.relay.backend import Runtime
 from tvm.contrib import cc as _cc
-from tvm.micro import copy_crt_config_header
 
 RUNTIMES = [
     (Runtime("crt", {"system-lib": True}), "{name}_c.{ext}"),
@@ -166,8 +165,3 @@ def transform_image(image):
     else:
         build_module(opts)
         build_inputs(opts)
-
-    crt_config_output_path = pathlib.Path(__file__).parent.resolve() / "build" / "crt_config"
-    if not crt_config_output_path.exists():
-        crt_config_output_path.mkdir()
-    copy_crt_config_header("crt", crt_config_output_path)
diff --git a/apps/microtvm/zephyr/template_project/CMakeLists.txt.template b/apps/microtvm/zephyr/template_project/CMakeLists.txt.template
index cec29e724882..a190505a2315 100644
--- a/apps/microtvm/zephyr/template_project/CMakeLists.txt.template
+++ b/apps/microtvm/zephyr/template_project/CMakeLists.txt.template
@@ -54,13 +54,12 @@ else()
   set(cmsis_includes "")
 endif()
 
+# Add CRT libraries
 set(CRT_LIBS <API_SERVER_CRT_LIBS>)
-set(CRT_LIB_BASE crt/src/runtime/crt)
+set(CRT_CONFIG_PATH ${CMAKE_SOURCE_DIR}/crt_config)
+add_subdirectory(crt)
 foreach(crt_lib_name ${CRT_LIBS})
-  zephyr_library_named(${crt_lib_name})
-  file(GLOB_RECURSE crt_lib_srcs ${CRT_LIB_BASE}/${crt_lib_name}/*.c ${CRT_LIB_BASE}/${crt_lib_name}/*.cc)
-  target_sources(${crt_lib_name} PRIVATE ${crt_lib_srcs})
-  zephyr_library_include_directories(${crt_lib_name} PRIVATE crt_config crt/include)
+  target_link_libraries(${crt_lib_name} PUBLIC zephyr_interface)
   target_link_libraries(app PRIVATE ${crt_lib_name})
 endforeach(crt_lib_name ${CRT_LIBS})
 
diff --git a/apps/microtvm/zephyr/template_project/microtvm_api_server.py b/apps/microtvm/zephyr/template_project/microtvm_api_server.py
index 227b0389445a..8a792ff41e8d 100644
--- a/apps/microtvm/zephyr/template_project/microtvm_api_server.py
+++ b/apps/microtvm/zephyr/template_project/microtvm_api_server.py
@@ -383,7 +383,7 @@ def server_info_query(self, tvm_version):
         )
 
     # These files and directories will be recursively copied into generated projects from the CRT.
-    CRT_COPY_ITEMS = ("include", "Makefile", "src")
+    CRT_COPY_ITEMS = ("include", "CMakeLists.txt", "src")
 
     # Maps extra line added to prj.conf to a tuple or list of zephyr_board for which it is needed.
     EXTRA_PRJ_CONF_DIRECTIVES = {
diff --git a/cmake/modules/StandaloneCrt.cmake b/cmake/modules/StandaloneCrt.cmake
index 77025d77b7f9..f6a3c6d4108e 100644
--- a/cmake/modules/StandaloneCrt.cmake
+++ b/cmake/modules/StandaloneCrt.cmake
@@ -79,7 +79,7 @@ if(USE_MICRO)
         "include/tvm/runtime c_*_api.h -> include/tvm/runtime"
         "include/tvm/runtime metadata_types.h -> include/tvm/runtime"
         "include/tvm/runtime/crt *.h -> include/tvm/runtime/crt"
-        "src/runtime/crt Makefile -> ."
+        "src/runtime/crt CMakeLists.txt -> ."
         "src/runtime/crt/include *.h -> include"
         "src/runtime/crt/aot_executor *.c -> src/runtime/crt/aot_executor"
         "src/runtime/crt/aot_executor_module *.c -> src/runtime/crt/aot_executor_module"
diff --git a/src/runtime/crt/CMakeLists.txt b/src/runtime/crt/CMakeLists.txt
new file mode 100644
index 000000000000..ea170bca1c86
--- /dev/null
+++ b/src/runtime/crt/CMakeLists.txt
@@ -0,0 +1,51 @@
+# Licensed to the Apache Software Foundation (ASF) under one
+# or more contributor license agreements.  See the NOTICE file
+# distributed with this work for additional information
+# regarding copyright ownership.  The ASF licenses this file
+# to you under the Apache License, Version 2.0 (the
+# "License"); you may not use this file except in compliance
+# with the License.  You may obtain a copy of the License at
+#
+#   http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing,
+# software distributed under the License is distributed on an
+# "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
+# KIND, either express or implied.  See the License for the
+# specific language governing permissions and limitations
+# under the License.
+
+# SPDX-License-Identifier: Apache-2.0
+
+cmake_minimum_required(VERSION 3.18)
+project(standalone_crt_libs C CXX)
+
+if(NOT DEFINED CRT_CONFIG_PATH)
+  message(FATAL_ERROR "Must supply path to crt_config.h: CRT_CONFIG_PATH=...")
+endif()
+
+set(CRT_LIB_BASE ${CMAKE_CURRENT_SOURCE_DIR}/src/runtime/crt)
+if(NOT EXISTS "${CRT_LIB_BASE}")
+    message(FATAL_ERROR
+    "This CMakeList does not build inside TVM source tree.
+Build the standalone_crt target, and re-invoke CMakeList.txt in build/standalone_crt.")
+endif()
+
+if (NOT DEFINED CRT_LIBS)
+  set(CRT_LIBS microtvm_rpc_server
+    microtvm_rpc_common
+    aot_executor_module
+    aot_executor
+    graph_executor_module
+    graph_executor
+    common
+    memory
+  )
+endif()
+
+foreach(crt_lib_name ${CRT_LIBS})
+  add_library(${crt_lib_name})
+  file(GLOB_RECURSE crt_lib_srcs ${CRT_LIB_BASE}/${crt_lib_name}/*.c ${CRT_LIB_BASE}/${crt_lib_name}/*.cc)
+  target_sources(${crt_lib_name} PRIVATE ${crt_lib_srcs})
+  target_include_directories(${crt_lib_name} PRIVATE include ${CRT_CONFIG_PATH})
+endforeach(crt_lib_name ${CRT_LIBS})
diff --git a/src/runtime/crt/Makefile b/src/runtime/crt/Makefile
deleted file mode 100644
index a9987b8b7cb1..000000000000
--- a/src/runtime/crt/Makefile
+++ /dev/null
@@ -1,85 +0,0 @@
-# Licensed to the Apache Software Foundation (ASF) under one
-# or more contributor license agreements.  See the NOTICE file
-# distributed with this work for additional information
-# regarding copyright ownership.  The ASF licenses this file
-# to you under the Apache License, Version 2.0 (the
-# "License"); you may not use this file except in compliance
-# with the License.  You may obtain a copy of the License at
-#
-#   http://www.apache.org/licenses/LICENSE-2.0
-#
-# Unless required by applicable law or agreed to in writing,
-# software distributed under the License is distributed on an
-# "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
-# KIND, either express or implied.  See the License for the
-# specific language governing permissions and limitations
-# under the License.
-
-# NOTE: Although this Makefile contains build commands for the C runtime, it isn't intended to be
-# used directly in the TVM source tree. Instead, build the "standalone_crt" target, which produces a
-# directory tree suitable for this Makefile. If this Makefile looks like it's the top-level of a
-# source tree, you can probably ignore this message.
-
-# NOTE: If files appear to be missing in the generated standalone_crt target, consult the copy job
-# specs listed in the TVM repo in cmake/modules/StandaloneCrt.cmake.
-
-ifeq ($(CRT_CONFIG),)
-$(error "Must supply path to crt_config.h: CRT_CONFIG=...")
-endif
-
-ifneq ($(wildcard .gitignore),)
-$(error "detected building inside tvm source tree.")
-$(error "build the standalone_crt target, and re-invoke makefile in build/standalone_crt")
-endif
-
-BUILD_DIR ?= build
-PREFIX ?=
-
-AR ?= ${PREFIX}ar
-CC ?= ${PREFIX}gcc
-CXX ?= ${PREFIX}g++
-RANLIB ?= ${PREFIX}ranlib
-
-QUIET ?= @
-
-CRT_PREFIX = $(wildcard src/crt)
-
-INCLUDES ?= -isystem include -iquote $(dir ${CRT_CONFIG})
-CFLAGS += ${INCLUDES} -Werror -g $(EXTRA_CFLAGS) -DDMLC_USE_LOGGING_LIBRARY=\<tvm/runtime/logging.h\>
-CXXFLAGS += ${INCLUDES} -std=c++11 -Werror -g $(EXTRA_CXXFLAGS) -DDMLC_USE_LOGGING_LIBRARY=\<tvm/runtime/logging.h\>
-LDFLAGS += -Werror -g $(EXTRA_LDFLAGS)
-
-${BUILD_DIR}/%.o: src/%.c $(CRT_CONFIG)
-	${QUIET}mkdir -p $(dir $@)
-	${QUIET}${CC} ${CFLAGS} -c -o "$@" "$<"
-
-${BUILD_DIR}/%.o: src/%.cc $(CRT_CONFIG)
-	${QUIET}mkdir -p $(dir $@)
-	${QUIET}${CXX} ${CXXFLAGS} -c -o "$@" "$<"
-
-define LIB_template
-$${BUILD_DIR}/lib$(notdir $(1)).a: $$(patsubst src/%.c,$${BUILD_DIR}/%.o,$$(wildcard src/$(1:src/%=%)/*.c)) $$(patsubst src/%.cc,${BUILD_DIR}/%.o,$$(wildcard src/$(1:src/%=%)/*.cc))
-	$${QUIET}$${AR} -cr "$$@" $$^
-	$${QUIET}$${RANLIB} $${RANLIBFLAGS} "$$@"
-$(notdir $(1)): $${BUILD_DIR}/lib$(notdir $(1)).a
-
-endef
-
-LIBS = \
-	src/runtime/crt/aot_executor \
-	src/runtime/crt/aot_executor_module \
-	src/runtime/crt/common \
-	src/runtime/crt/graph_executor \
-	src/runtime/crt/graph_executor_module \
-	src/runtime/crt/memory \
-	src/runtime/crt/microtvm_rpc_common \
-	src/runtime/crt/microtvm_rpc_server
-
-$(foreach lib,$(LIBS),$(eval $(call LIB_template,$(lib))))
-
-all: $(notdir $(LIBS))
-clean:
-	rm -rf "${BUILD_DIR}"
-
-.PHONY: all $(notdir $(LIBS))
-.DEFAULT_GOAL: all
diff --git a/src/runtime/crt/host/microtvm_api_server.py b/src/runtime/crt/host/microtvm_api_server.py
index af6947a18b9c..7271c4512abc 100644
--- a/src/runtime/crt/host/microtvm_api_server.py
+++ b/src/runtime/crt/host/microtvm_api_server.py
@@ -79,7 +79,7 @@ def server_info_query(self, tvm_version):
         )
 
     # These files and directories will be recursively copied into generated projects from the CRT.
-    CRT_COPY_ITEMS = ("include", "Makefile", "src")
+    CRT_COPY_ITEMS = ("include", "CMakeLists.txt", "src")
 
     def _populate_cmake(
         self,