diff --git a/src/codegen/llvm/codegen_llvm.cc b/src/codegen/llvm/codegen_llvm.cc
index 215a6c9c5b1b..52f1c20134f2 100644
--- a/src/codegen/llvm/codegen_llvm.cc
+++ b/src/codegen/llvm/codegen_llvm.cc
@@ -647,6 +647,8 @@ llvm::Value* CodeGenLLVM::CreateIntrinsic(const Call* op) {
   } else if (op->is_intrinsic(intrinsic::tvm_handle_is_null)) {
     return builder_->CreateIsNull(MakeValue(op->args[0]));
   } else if (op->is_intrinsic(intrinsic::tvm_if_then_else)) {
+    CHECK_EQ(op->args[0].type().lanes(), 1)
+        << "if_then_else can only take scalar condition";
     using llvm::BasicBlock;
     BasicBlock* then_block = BasicBlock::Create(
         *ctx_, "if_then", function_);
diff --git a/src/pass/vectorize_loop.cc b/src/pass/vectorize_loop.cc
index 19874a803657..282f1eee1399 100644
--- a/src/pass/vectorize_loop.cc
+++ b/src/pass/vectorize_loop.cc
@@ -83,6 +83,19 @@ class Vectorizer : public IRMutator {
   // user mutate from parent.
   using IRMutator::Mutate;
 
+  Stmt Mutate(Stmt stmt) final {
+    CHECK(!need_scalarize_);
+
+    Stmt ret = IRMutator::Mutate(stmt);
+    if (need_scalarize_) {
+      need_scalarize_ = false;
+      return Scalarize(stmt);
+    } else {
+      return ret;
+    }
+  }
+
+
   Expr Mutate_(const Add* op, const Expr &e) final {
     return AddSubVec(op, e);
   }
@@ -200,10 +213,37 @@ class Vectorizer : public IRMutator {
       return e;
     }
   }
+  // IfThenElse expr
+  Expr MutateIfThenElseExpr_(const Call *op, const Expr& e) {
+    Expr cond = this->Mutate(op->args[0]);
+    if (cond.type().is_vector())  {
+      need_scalarize_ = true;
+      return e;
+    }
+    Expr t = this->Mutate(op->args[1]);
+    Expr f = this->Mutate(op->args[2]);
+    if (cond.same_as(op->args[0]) &&
+        t.same_as(op->args[1]) &&
+        f.same_as(op->args[2])) {
+      return e;
+    } else {
+      int lanes = std::max(t.type().lanes(), f.type().lanes());
+      t = BroadcastTo(t, lanes);
+      f = BroadcastTo(f, lanes);
+      return Call::make(
+          op->type.with_lanes(lanes), op->name,
+          {cond, t, f}, op->call_type, op->func, op->value_index);
+    }
+  }
   // Call
   Expr Mutate_(const Call* op, const Expr& e) final {
+    if (op->name == intrinsic::tvm_if_then_else) {
+      return MutateIfThenElseExpr_(op, e);
+    }
     int lane = 0;
     Array<Expr> new_args = MutateArray(op->args, &lane);
+
+    // normal code path.
     if (op->args.same_as(new_args)) {
       return e;
     } else {
@@ -367,6 +407,8 @@ class Vectorizer : public IRMutator {
   int var_lanes_;
   // ramp representing the var.
   Expr ramp_;
+  // flag to mark requirment of scalarization.
+  bool need_scalarize_{false};
   // The lets
   std::unordered_map<const Variable*, Expr> lets_;
   // mutate array, with given lane requirement
diff --git a/tests/python/unittest/test_pass_vectorize.py b/tests/python/unittest/test_pass_vectorize.py
index 45bb4362d68e..1fbcc655ac80 100644
--- a/tests/python/unittest/test_pass_vectorize.py
+++ b/tests/python/unittest/test_pass_vectorize.py
@@ -53,7 +53,36 @@ def test_vectorize_with_if():
     assert stmt.then_case.value.dtype == "float32x4"
     assert isinstance(stmt.else_case, tvm.stmt.For)
 
+def test_vectorize_if_then_else():
+    n = tvm.var('n')
+    x = tvm.var('x')
+    ib = tvm.ir_builder.create()
+    A = ib.pointer("float32", name="A")
+    with ib.for_range(0, 4, for_type="vectorize") as i:
+        A[i] = tvm.call_intrin("float32", "tvm_if_then_else",
+                               i > 0,
+                               A[i] + 1, A[i])
+    stmt = ib.get()
+    stmt = tvm.ir_pass.VectorizeLoop(stmt)
+    assert isinstance(stmt, tvm.stmt.For)
+
+
+    ib = tvm.ir_builder.create()
+    A = ib.pointer("float32", name="A")
+    with ib.for_range(0, n) as k:
+        with ib.for_range(0, 4, for_type="vectorize") as i:
+            A[k * 4 + i] = tvm.call_intrin("float32", "tvm_if_then_else",
+                                           k > 0,
+                                           A[k * 4 + i], 0)
+    stmt = ib.get()
+    assert isinstance(stmt.body, tvm.stmt.For)
+    stmt = tvm.ir_pass.VectorizeLoop(stmt)
+    assert not isinstance(stmt.body, tvm.stmt.For)
+    assert isinstance(stmt.body.value.args[2], tvm.expr.Broadcast)
+
+
 if __name__ == "__main__":
     test_vectorize_vector()
     test_vectorize_with_if()
     test_vectorize_loop()
+    test_vectorize_if_then_else()