diff --git a/CHANGELOG.md b/CHANGELOG.md
index 415b936e8d..fe68ce1ac9 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -34,6 +34,9 @@ A brief description of the categories of changes:
 * (whl_library): Fix the experimental_target_platforms overriding for platform
   specific wheels when the wheels are for any python interpreter version. Fixes
   [#1810](https://github.com/bazelbuild/rules_python/issues/1810).
+* (whl_library): Stop generating duplicate dependencies when encountering
+  duplicates in the METADATA. Fixes
+  [#1873](https://github.com/bazelbuild/rules_python/issues/1873).
 * (gazelle) In `project` or `package` generation modes, do not generate `py_test`
   rules when there are no test files and do not set `main = "__test__.py"` when
   that file doesn't exist.
diff --git a/python/pip_install/tools/wheel_installer/wheel.py b/python/pip_install/tools/wheel_installer/wheel.py
index 750ebfcf7a..f7c686d9ba 100644
--- a/python/pip_install/tools/wheel_installer/wheel.py
+++ b/python/pip_install/tools/wheel_installer/wheel.py
@@ -370,6 +370,24 @@ def _add(self, dep: str, platform: Optional[Platform]):
 
         if not platform:
             self._deps.add(dep)
+
+            # If the dep is in the platform-specific list, remove it from the select.
+            pop_keys = []
+            for p, deps in self._select.items():
+                if dep not in deps:
+                    continue
+
+                deps.remove(dep)
+                if not deps:
+                    pop_keys.append(p)
+
+            for p in pop_keys:
+                self._select.pop(p)
+            return
+
+        if dep in self._deps:
+            # If the dep is already in the main dependency list, no need to add it in the
+            # platform-specific dependency list.
             return
 
         # Add the platform-specific dep
diff --git a/python/pip_install/tools/wheel_installer/wheel_test.py b/python/pip_install/tools/wheel_installer/wheel_test.py
index f7c847fc9e..20141e2867 100644
--- a/python/pip_install/tools/wheel_installer/wheel_test.py
+++ b/python/pip_install/tools/wheel_installer/wheel_test.py
@@ -264,6 +264,48 @@ def test_deps_spanning_all_target_py_versions_are_added_to_common(self):
         self.assertEqual(["bar", "baz"], got.deps)
         self.assertEqual({}, got.deps_select)
 
+    def test_deps_are_not_duplicated(self):
+        # See an example in
+        # https://files.pythonhosted.org/packages/76/9e/db1c2d56c04b97981c06663384f45f28950a73d9acf840c4006d60d0a1ff/opencv_python-4.9.0.80-cp37-abi3-win32.whl.metadata
+        requires_dist = [
+            "bar >=0.1.0 ; python_version < '3.7'",
+            "bar >=0.2.0 ; python_version >= '3.7'",
+            "bar >=0.4.0 ; python_version >= '3.6' and platform_system == 'Linux' and platform_machine == 'aarch64'",
+            "bar >=0.4.0 ; python_version >= '3.9'",
+            "bar >=0.5.0 ; python_version <= '3.9' and platform_system == 'Darwin' and platform_machine == 'arm64'",
+            "bar >=0.5.0 ; python_version >= '3.10' and platform_system == 'Darwin'",
+            "bar >=0.5.0 ; python_version >= '3.10'",
+            "bar >=0.6.0 ; python_version >= '3.11'",
+        ]
+
+        deps = wheel.Deps(
+            "foo",
+            requires_dist=requires_dist,
+            platforms=wheel.Platform.from_string(["cp310_*"]),
+        )
+        got = deps.build()
+
+        self.assertEqual(["bar"], got.deps)
+        self.assertEqual({}, got.deps_select)
+
+    def test_deps_are_not_duplicated_when_encountering_platform_dep_first(self):
+        # Note, that we are sorting the incoming `requires_dist` and we need to ensure that we are not getting any
+        # issues even if the platform-specific line comes first.
+        requires_dist = [
+            "bar >=0.4.0 ; python_version >= '3.6' and platform_system == 'Linux' and platform_machine == 'aarch64'",
+            "bar >=0.5.0 ; python_version >= '3.9'",
+        ]
+
+        deps = wheel.Deps(
+            "foo",
+            requires_dist=requires_dist,
+            platforms=wheel.Platform.from_string(["cp310_*"]),
+        )
+        got = deps.build()
+
+        self.assertEqual(["bar"], got.deps)
+        self.assertEqual({}, got.deps_select)
+
 
 class MinorVersionTest(unittest.TestCase):
     def test_host(self):