diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index 528f981..f8c9808 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -24,10 +24,14 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        os: [ubuntu-latest]
+        os: [ubuntu-latest, macos-latest]
 
     steps:
 
+      - name: Install X11 dependencies (macOS)
+        if: runner.os == 'macOS'
+        run: brew install libx11 libxpm pkg-config
+
       - name: install X11 dependencies
         if: ${{ runner.os == 'Linux' }}
         run: |
@@ -90,7 +94,8 @@ jobs:
       - name: Download build artifacts from this run
         uses: actions/download-artifact@v4
         with:
-          name: vmol-wheels-${{ runner.os }}-${{ github.ref_name }}-${{ github.run_number }}
+          pattern: vmol-wheels-*-${{ github.ref_name }}-${{ github.run_number }}
+          merge-multiple: true
           path: dist
 
       - name: Publish to TestPyPI
diff --git a/.github/workflows/wheels.yml b/.github/workflows/wheels.yml
index b13b176..7d4e1dd 100644
--- a/.github/workflows/wheels.yml
+++ b/.github/workflows/wheels.yml
@@ -1,6 +1,28 @@
 name: Build wheels
 
 on:
+  workflow_dispatch:
+    inputs:
+      package-dir:
+        type: string
+        required: false
+        default: ./python
+      output-dir:
+        type: string
+        required: false
+        default: wheelhouse
+      cibw-build:
+        type: string
+        required: false
+        default: ""
+      cibw-skip:
+        type: string
+        required: false
+        default: "*-musllinux_*"
+      upload-artifact:
+        type: boolean
+        required: false
+        default: true
   workflow_call:
     inputs:
       package-dir:
@@ -26,8 +48,11 @@ on:
 
 jobs:
   build_wheels:
-    name: Build wheels
-    runs-on: ubuntu-latest
+    name: Build wheels on ${{ matrix.os }}
+    runs-on: ${{ matrix.os }}
+    strategy:
+      matrix:
+        os: [ubuntu-latest, macos-latest]
 
     steps:
 
@@ -56,6 +81,12 @@ jobs:
         env:
           CIBW_BUILD: ${{ inputs.cibw-build }}
           CIBW_SKIP: ${{ inputs.cibw-skip }}
+          CIBW_BEFORE_ALL_MACOS: |
+            brew install libx11 libxpm pkg-config
+          CIBW_ENVIRONMENT_MACOS: MACOSX_DEPLOYMENT_TARGET=15.0
+          CIBW_REPAIR_WHEEL_COMMAND_MACOS: >
+            DYLD_LIBRARY_PATH=$(brew --prefix)/lib
+            delocate-wheel --require-archs {delocate_archs} -w {dest_dir} -v {wheel}
           CIBW_BEFORE_ALL_LINUX: |
             if [ -f /etc/alpine-release ]; then # musllinux (Alpine)
               apk add --no-cache libx11-dev libxpm-dev pkgconf
diff --git a/.gitignore b/.gitignore
index 9c6ac0f..b5f9e8a 100644
--- a/.gitignore
+++ b/.gitignore
@@ -10,3 +10,4 @@ vmol.egg-info/
 python/build
 python/dist
 python/src
+wheelhouse/
diff --git a/python/setup.py b/python/setup.py
index 6da5c76..ade1d46 100644
--- a/python/setup.py
+++ b/python/setup.py
@@ -1,6 +1,7 @@
 from setuptools import setup, Extension
 import subprocess
 import os
+import sys
 import tempfile
 import shutil
 from pathlib import Path
@@ -29,6 +30,32 @@ def rel_posix(path):
     return os.path.relpath(path, start=setup_dir).replace(os.sep, "/")
 
 
+def get_x11_config():
+    # On Linux, X11 headers/libs are in standard system paths — nothing extra needed.
+    # On macOS, Homebrew installs them to non-default locations, so we probe for them.
+    if sys.platform != 'darwin':
+        return [], []
+    try:
+        inc = subprocess.run(
+            ['pkg-config', '--cflags-only-I', 'x11', 'xpm'],
+            check=True, stdout=subprocess.PIPE, stderr=subprocess.DEVNULL, text=True,
+        ).stdout.split()
+        lib = subprocess.run(
+            ['pkg-config', '--libs-only-L', 'x11', 'xpm'],
+            check=True, stdout=subprocess.PIPE, stderr=subprocess.DEVNULL, text=True,
+        ).stdout.split()
+        return [f[2:] for f in inc if f.startswith('-I')], \
+               [f[2:] for f in lib if f.startswith('-L')]
+    except Exception:
+        pass
+    for prefix in ['/opt/homebrew', '/usr/local']:
+        if Path(f'{prefix}/include/X11/Xlib.h').exists():
+            return [f'{prefix}/include'], [f'{prefix}/lib']
+    raise RuntimeError(
+        'X11 headers not found. Install with: brew install libx11 libxpm pkg-config'
+    )
+
+
 setup_dir = Path(__file__).parent
 src_dir = setup_dir.parent / "src"
 
@@ -45,12 +72,15 @@ def rel_posix(path):
                  f'-DBUILD_USER="{os.getenv("USER")}@{os.getenv("HOSTNAME")}"',
                  f'-DBUILD_DIRECTORY="{os.getcwd()}"']
 
+x11_inc, x11_lib = get_x11_config()
+
 setup(
     version=get_git_version_hash(),
     include_package_data=True,
     ext_modules=[Extension('vmol.v',
                            sources=c_files,
-                           include_dirs=include_dirs,
+                           include_dirs=include_dirs + x11_inc,
+                           library_dirs=x11_lib,
 
                            libraries = ['X11', 'Xpm'],
                            extra_compile_args=['-std=gnu11', '-O2', ] + VERSION_FLAGS,