diff --git a/docs/release-notes/.FSharp.Compiler.Service/8.0.200.md b/docs/release-notes/.FSharp.Compiler.Service/8.0.200.md
index d590359564a..65f52c982fa 100644
--- a/docs/release-notes/.FSharp.Compiler.Service/8.0.200.md
+++ b/docs/release-notes/.FSharp.Compiler.Service/8.0.200.md
@@ -16,10 +16,6 @@
 * `MutableKeyword` to [SynFieldTrivia](../reference/fsharp-compiler-syntaxtrivia-synfieldtrivia.html) ([PR #16357](https://github.com/dotnet/fsharp/pull/16357))
 * Added support for a new parameterless constructor for `CustomOperationAttribute`, which, when applied, will use method name as keyword for custom operation in computation expression builder. ([PR #16475](https://github.com/dotnet/fsharp/pull/16475), part of implementation for [fslang-suggestions/1250](https://github.com/fsharp/fslang-suggestions/issues/1250))
 
-* Parser recovers on complex primary constructor patterns, better tree representation for primary constructor patterns. ([PR #16425](https://github.com/dotnet/fsharp/pull/16425))
-
 ### Changed
-* `implicitCtorSynPats` in `SynTypeDefnSimpleRepr.General` is now `SynPat option` instead of `SynSimplePats option`. ([PR #16425](https://github.com/dotnet/fsharp/pull/16425))
-* `SyntaxVisitorBase<'T>.VisitSimplePats` now takes `SynPat` instead of `SynSimplePat list`. ([PR #16425](https://github.com/dotnet/fsharp/pull/16425))
-* Speed up unused opens handling for empty results. ([PR #16502](https://github.com/dotnet/fsharp/pull/16502))
 
+* Speed up unused opens handling for empty results. ([PR #16502](https://github.com/dotnet/fsharp/pull/16502))
\ No newline at end of file
diff --git a/docs/release-notes/.FSharp.Compiler.Service/8.0.300.md b/docs/release-notes/.FSharp.Compiler.Service/8.0.300.md
new file mode 100644
index 00000000000..ac442a61549
--- /dev/null
+++ b/docs/release-notes/.FSharp.Compiler.Service/8.0.300.md
@@ -0,0 +1,12 @@
+### Fixed
+
+* Code generated files with > 64K methods and generated symbols crash when loaded. Use infered sequence points for debugging. ([Issue #16399](https://github.com/dotnet/fsharp/issues/16399), [#PR 16514](https://github.com/dotnet/fsharp/pull/16514))
+
+### Added
+
+* Parser recovers on complex primary constructor patterns, better tree representation for primary constructor patterns. ([PR #16425](https://github.com/dotnet/fsharp/pull/16425))
+
+### Changed
+
+* `implicitCtorSynPats` in `SynTypeDefnSimpleRepr.General` is now `SynPat option` instead of `SynSimplePats option`. ([PR #16425](https://github.com/dotnet/fsharp/pull/16425))
+* `SyntaxVisitorBase<'T>.VisitSimplePats` now takes `SynPat` instead of `SynSimplePat list`. ([PR #16425](https://github.com/dotnet/fsharp/pull/16425))
\ No newline at end of file
diff --git a/src/Compiler/Driver/CreateILModule.fs b/src/Compiler/Driver/CreateILModule.fs
index 7bc9be6b373..04cda7f6c3f 100644
--- a/src/Compiler/Driver/CreateILModule.fs
+++ b/src/Compiler/Driver/CreateILModule.fs
@@ -409,7 +409,7 @@ module MainModuleBuilder =
                     yield! codegenResults.ilAssemAttrs
 
                     if Option.isSome pdbfile then
-                        tcGlobals.mkDebuggableAttributeV2 (tcConfig.jitTracking, disableJitOptimizations, false (* enableEnC *) )
+                        tcGlobals.mkDebuggableAttributeV2 (tcConfig.jitTracking, disableJitOptimizations)
                     yield! reflectedDefinitionAttrs
                 ]
 
diff --git a/src/Compiler/TypedTree/TcGlobals.fs b/src/Compiler/TypedTree/TcGlobals.fs
index 0bbee0c3e55..3830dd008e5 100644
--- a/src/Compiler/TypedTree/TcGlobals.fs
+++ b/src/Compiler/TypedTree/TcGlobals.fs
@@ -1852,11 +1852,11 @@ type TcGlobals(
 
   member _.DebuggerBrowsableNeverAttribute = debuggerBrowsableNeverAttribute
 
-  member _.mkDebuggableAttributeV2(jitTracking, jitOptimizerDisabled, enableEnC) =
+  member _.mkDebuggableAttributeV2(jitTracking, jitOptimizerDisabled) =
         let debuggingMode =
+            0x3 (* Default ||| IgnoreSymbolStoreSequencePoints *) |||
             (if jitTracking then 1 else 0) |||
-            (if jitOptimizerDisabled then 256 else 0) |||
-            (if enableEnC then 4 else 0)
+            (if jitOptimizerDisabled then 256 else 0)
         let tref_DebuggableAttribute_DebuggingModes = mkILTyRefInTyRef (tref_DebuggableAttribute, tname_DebuggableAttribute_DebuggingModes)
         mkILCustomAttribute
           (tref_DebuggableAttribute, [mkILNonGenericValueTy tref_DebuggableAttribute_DebuggingModes],