diff --git a/src/coreclr/nativeaot/BuildIntegration/Microsoft.NETCore.Native.targets b/src/coreclr/nativeaot/BuildIntegration/Microsoft.NETCore.Native.targets
index 348c20b9fcbf33..48661e898336f2 100644
--- a/src/coreclr/nativeaot/BuildIntegration/Microsoft.NETCore.Native.targets
+++ b/src/coreclr/nativeaot/BuildIntegration/Microsoft.NETCore.Native.targets
@@ -247,7 +247,7 @@ The .NET Foundation licenses this file to you under the MIT license.
       <IlcArg Condition="$(_targetOS) != ''" Include="--targetos:$(_targetOS)" />
       <IlcArg Condition="$(_targetArchitectureWithAbi) != ''" Include="--targetarch:$(_targetArchitectureWithAbi)" />
       <IlcArg Condition="$(IlcMultiModule) == 'true'" Include="--multifile" />
-      <IlcArg Condition="$(IlcMultiModule) != 'true' and '$(IlcDehydrate)' != 'false'" Include="--dehydrate" />
+      <IlcArg Condition="$(IlcMultiModule) != 'true' and '$(IlcDehydrate)' != 'false' and ($(_targetOS) != 'win' or '$(OptimizationPreference)' == 'Size' or '$(IlcDehydrate)' == 'true')" Include="--dehydrate" />
       <IlcArg Condition="$(Optimize) == 'true'" Include="-O" />
       <IlcArg Condition="$(NativeDebugSymbols) == 'true'" Include="-g" />
       <IlcArg Condition="$(IlcDwarfVersion) == '5'" Include="--gdwarf-5" />