diff --git a/src/coreclr/tools/aot/ILCompiler.RyuJit/JitInterface/CorInfoImpl.RyuJit.cs b/src/coreclr/tools/aot/ILCompiler.RyuJit/JitInterface/CorInfoImpl.RyuJit.cs
index 92e0d41bd92677..c64ff0f1b49699 100644
--- a/src/coreclr/tools/aot/ILCompiler.RyuJit/JitInterface/CorInfoImpl.RyuJit.cs
+++ b/src/coreclr/tools/aot/ILCompiler.RyuJit/JitInterface/CorInfoImpl.RyuJit.cs
@@ -2282,7 +2282,7 @@ private bool CanNeverHaveInstanceOfSubclassOf(TypeDesc type)
         private int getExactClasses(CORINFO_CLASS_STRUCT_* baseType, int maxExactClasses, CORINFO_CLASS_STRUCT_** exactClsRet)
         {
             MetadataType type = HandleToObject(baseType) as MetadataType;
-            if (type == null)
+            if (type == null || type.HasVariance)
             {
                 return -1;
             }