diff --git a/src/coreclr/clrdefinitions.cmake b/src/coreclr/clrdefinitions.cmake
index 60b79850f53ffd..6ad026ec0254a5 100644
--- a/src/coreclr/clrdefinitions.cmake
+++ b/src/coreclr/clrdefinitions.cmake
@@ -173,10 +173,10 @@ endif (CLR_CMAKE_HOST_UNIX AND CLR_CMAKE_TARGET_UNIX)
 if (FEATURE_ENABLE_NO_ADDRESS_SPACE_RANDOMIZATION)
   add_definitions(-DFEATURE_ENABLE_NO_ADDRESS_SPACE_RANDOMIZATION)
 endif(FEATURE_ENABLE_NO_ADDRESS_SPACE_RANDOMIZATION)
-if (NOT CLR_CMAKE_HOST_ANDROID)
+if (NOT CLR_CMAKE_HOST_ANDROID AND NOT CLR_CMAKE_TARGET_ARCH_WASM AND NOT CLR_CMAKE_TARGET_IOS AND NOT CLR_CMAKE_TARGET_TVOS)
   set(FEATURE_SVR_GC 1)
   add_definitions(-DFEATURE_SVR_GC)
-endif(NOT CLR_CMAKE_HOST_ANDROID)
+endif(NOT CLR_CMAKE_HOST_ANDROID AND NOT CLR_CMAKE_TARGET_ARCH_WASM AND NOT CLR_CMAKE_TARGET_IOS AND NOT CLR_CMAKE_TARGET_TVOS)
 add_definitions(-DFEATURE_SYMDIFF)
 
 if (FEATURE_TIERED_COMPILATION)