diff --git a/src/libraries/System.Linq/src/System/Linq/Sum.cs b/src/libraries/System.Linq/src/System/Linq/Sum.cs
index 481997b8f82633..a9187f9ebb40b6 100644
--- a/src/libraries/System.Linq/src/System/Linq/Sum.cs
+++ b/src/libraries/System.Linq/src/System/Linq/Sum.cs
@@ -5,7 +5,6 @@
 using System.Diagnostics;
 using System.Numerics;
 using System.Runtime.CompilerServices;
-using System.Runtime.InteropServices;
 
 namespace System.Linq
 {
@@ -84,9 +83,6 @@ private static T SumSignedIntegersVectorized<T>(ReadOnlySpan<T> span)
             Debug.Assert(Vector<T>.Count > 2);
             Debug.Assert(Vector.IsHardwareAccelerated);
 
-            ref T ptr = ref MemoryMarshal.GetReference(span);
-            nuint length = (nuint)span.Length;
-
             // Overflow testing for vectors is based on setting the sign bit of the overflowTracking
             // vector for an element if the following are all true:
             //   - The two elements being summed have the same sign bit. If one element is positive
@@ -104,71 +100,59 @@ private static T SumSignedIntegersVectorized<T>(ReadOnlySpan<T> span)
             // Thus, if we had a sign swap compared to both inputs, then signof(input1) == signof(input2) and
             // we must have overflowed.
             //
-            // By bitwise or-ing the overflowTracking vector for each step we can save cycles by testing
-            // the sign bits less often. If any iteration has the sign bit set in any element it indicates
-            // there was an overflow.
+            // By bitwise or-ing the overflowTracking vector throughout the entire loop and
+            // only testing it once at the end we save the cost of an in-loop test+branch per
+            // iteration. If any accumulation across the whole input has the sign bit set in
+            // any element it indicates there was an overflow.
             //
             // Note: The overflow checking in this algorithm is only correct for signed integers.
             // If support is ever added for unsigned integers then the overflow check should be:
             //   overflowTracking |= (input1 & input2) | Vector.AndNot(input1 | input2, result);
 
             Vector<T> accumulator = Vector<T>.Zero;
+            Vector<T> overflowTracking = Vector<T>.Zero;
 
             // Build a test vector with only the sign bit set in each element.
             Vector<T> overflowTestVector = new(T.MinValue);
 
-            // Unroll the loop to sum 4 vectors per iteration. This reduces range check
-            // and overflow check frequency, allows us to eliminate move operations swapping
-            // accumulators, and may have pipelining benefits.
-            nuint index = 0;
-            nuint limit = length - (nuint)Vector<T>.Count * 4;
-            do
+            // Unroll the loop to sum 4 vectors per iteration. This allows us to eliminate
+            // move operations swapping accumulators, and may have pipelining benefits.
+            while (span.Length >= Vector<T>.Count * 4)
             {
                 // Switch accumulators with each step to avoid an additional move operation
-                Vector<T> data = Vector.LoadUnsafe(ref ptr, index);
+                Vector<T> data = Vector.Create(span);
                 Vector<T> accumulator2 = accumulator + data;
-                Vector<T> overflowTracking = (accumulator2 ^ accumulator) & (accumulator2 ^ data);
+                overflowTracking |= (accumulator2 ^ accumulator) & (accumulator2 ^ data);
 
-                data = Vector.LoadUnsafe(ref ptr, index + (nuint)Vector<T>.Count);
+                data = Vector.Create(span.Slice(Vector<T>.Count));
                 accumulator = accumulator2 + data;
                 overflowTracking |= (accumulator ^ accumulator2) & (accumulator ^ data);
 
-                data = Vector.LoadUnsafe(ref ptr, index + (nuint)Vector<T>.Count * 2);
+                data = Vector.Create(span.Slice(Vector<T>.Count * 2));
                 accumulator2 = accumulator + data;
                 overflowTracking |= (accumulator2 ^ accumulator) & (accumulator2 ^ data);
 
-                data = Vector.LoadUnsafe(ref ptr, index + (nuint)Vector<T>.Count * 3);
+                data = Vector.Create(span.Slice(Vector<T>.Count * 3));
                 accumulator = accumulator2 + data;
                 overflowTracking |= (accumulator ^ accumulator2) & (accumulator ^ data);
 
-                if ((overflowTracking & overflowTestVector) != Vector<T>.Zero)
-                {
-                    ThrowHelper.ThrowOverflowException();
-                }
-
-                index += (nuint)Vector<T>.Count * 4;
-            } while (index < limit);
+                span = span.Slice(Vector<T>.Count * 4);
+            }
 
             // Process remaining vectors, if any, without unrolling
-            limit = length - (nuint)Vector<T>.Count;
-            if (index < limit)
+            while (span.Length >= Vector<T>.Count)
             {
-                Vector<T> overflowTracking = Vector<T>.Zero;
-
-                do
-                {
-                    Vector<T> data = Vector.LoadUnsafe(ref ptr, index);
-                    Vector<T> accumulator2 = accumulator + data;
-                    overflowTracking |= (accumulator2 ^ accumulator) & (accumulator2 ^ data);
-                    accumulator = accumulator2;
+                Vector<T> data = Vector.Create(span);
+                Vector<T> accumulator2 = accumulator + data;
+                overflowTracking |= (accumulator2 ^ accumulator) & (accumulator2 ^ data);
+                accumulator = accumulator2;
 
-                    index += (nuint)Vector<T>.Count;
-                } while (index < limit);
+                span = span.Slice(Vector<T>.Count);
+            }
 
-                if ((overflowTracking & overflowTestVector) != Vector<T>.Zero)
-                {
-                    ThrowHelper.ThrowOverflowException();
-                }
+            if ((overflowTracking & overflowTestVector) != Vector<T>.Zero)
+            {
+                ThrowHelper.ThrowOverflowException();
             }
 
             // Add the elements in the vector horizontally.
@@ -180,11 +164,9 @@ private static T SumSignedIntegersVectorized<T>(ReadOnlySpan<T> span)
             }
 
             // Add any remaining elements
-            while (index < length)
+            foreach (T value in span)
             {
-                checked { result += Unsafe.Add(ref ptr, index); }
-
-                index++;
+                checked { result += value; }
             }
 
             return result;