diff --git a/src/coreclr/src/tools/crossgen2/Common/TypeSystem/Common/ExceptionStringID.cs b/src/coreclr/src/tools/crossgen2/Common/TypeSystem/Common/ExceptionStringID.cs
index 14800f0e739f96..7de12aa4fe0168 100644
--- a/src/coreclr/src/tools/crossgen2/Common/TypeSystem/Common/ExceptionStringID.cs
+++ b/src/coreclr/src/tools/crossgen2/Common/TypeSystem/Common/ExceptionStringID.cs
@@ -32,6 +32,8 @@ public enum ExceptionStringID
         InvalidProgramVararg,
         InvalidProgramCallVirtFinalize,
         InvalidProgramNativeCallable,
+        InvalidProgramCallAbstractMethod,
+        InvalidProgramCallVirtStatic,
 
         // BadImageFormatException
         BadImageFormatGeneric,
diff --git a/src/coreclr/src/tools/crossgen2/ILCompiler.ReadyToRun/JitInterface/CorInfoImpl.ReadyToRun.cs b/src/coreclr/src/tools/crossgen2/ILCompiler.ReadyToRun/JitInterface/CorInfoImpl.ReadyToRun.cs
index d38ca882b1dc09..70d61f327e35c5 100644
--- a/src/coreclr/src/tools/crossgen2/ILCompiler.ReadyToRun/JitInterface/CorInfoImpl.ReadyToRun.cs
+++ b/src/coreclr/src/tools/crossgen2/ILCompiler.ReadyToRun/JitInterface/CorInfoImpl.ReadyToRun.cs
@@ -915,7 +915,7 @@ private void ceeInfoGetCallInfo(
             // a static method would have never found an instance method.
             if (originalMethod.Signature.IsStatic && (flags & CORINFO_CALLINFO_FLAGS.CORINFO_CALLINFO_CALLVIRT) != 0)
             {
-                throw new BadImageFormatException();
+                ThrowHelper.ThrowInvalidProgramException(ExceptionStringID.InvalidProgramCallVirtStatic, originalMethod);
             }
 
             exactType = type;
@@ -1037,15 +1037,15 @@ private void ceeInfoGetCallInfo(
                 // Static methods are always direct calls
                 directCall = true;
             }
+            else if ((flags & CORINFO_CALLINFO_FLAGS.CORINFO_CALLINFO_CALLVIRT) == 0 || resolvedConstraint)
+            {
+                directCall = true;
+            }
             else if (targetMethod.OwningType.IsInterface && targetMethod.IsAbstract)
             {
                 // Backwards compat: calls to abstract interface methods are treated as callvirt
                 directCall = false;
             }
-            else if ((flags & CORINFO_CALLINFO_FLAGS.CORINFO_CALLINFO_CALLVIRT) == 0 || resolvedConstraint)
-            {
-                directCall = true;
-            }
             else
             {
                 bool devirt;
@@ -1090,6 +1090,14 @@ private void ceeInfoGetCallInfo(
 
             if (directCall)
             {
+                // Direct calls to abstract methods are not allowed
+                if (targetMethod.IsAbstract &&
+                    // Compensate for always treating delegates as direct calls above
+                    !(((flags & CORINFO_CALLINFO_FLAGS.CORINFO_CALLINFO_LDFTN) != 0) && ((flags & CORINFO_CALLINFO_FLAGS.CORINFO_CALLINFO_CALLVIRT) != 0) && !resolvedCallVirt))
+                {
+                    ThrowHelper.ThrowInvalidProgramException(ExceptionStringID.InvalidProgramCallAbstractMethod, targetMethod);
+                }
+
                 bool allowInstParam = (flags & CORINFO_CALLINFO_FLAGS.CORINFO_CALLINFO_ALLOWINSTPARAM) != 0;
 
                 if (!allowInstParam && canonMethod.RequiresInstArg())