diff --git a/src/libraries/System.Private.CoreLib/src/System/Array.cs b/src/libraries/System.Private.CoreLib/src/System/Array.cs
index d3753a1b6bf785..888f58689d0fb2 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Array.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Array.cs
@@ -51,7 +51,7 @@ public static void Resize<T>([NotNull] ref T[]? array, int newSize)
             if (newSize < 0)
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.newSize, ExceptionResource.ArgumentOutOfRange_NeedNonNegNum);
 
-            T[]? larray = array;
+            T[]? larray = array; // local copy
             if (larray == null)
             {
                 array = new T[newSize];
@@ -60,8 +60,17 @@ public static void Resize<T>([NotNull] ref T[]? array, int newSize)
 
             if (larray.Length != newSize)
             {
+                // Due to array variance, it's possible that the incoming array is
+                // actually of type U[], where U:T; or that an int[] <-> uint[] or
+                // similar cast has occurred. In any case, since it's always legal
+                // to reinterpret U as T in this scenario (but not necessarily the
+                // other way around), we can use Buffer.Memmove here.
+
                 T[] newArray = new T[newSize];
-                Copy(larray, 0, newArray, 0, larray.Length > newSize ? newSize : larray.Length);
+                Buffer.Memmove<T>(
+                    ref MemoryMarshal.GetArrayDataReference(newArray),
+                    ref MemoryMarshal.GetArrayDataReference(larray),
+                    (uint)Math.Min(newSize, larray.Length));
                 array = newArray;
             }
 
diff --git a/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/RuntimeHelpers.cs b/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/RuntimeHelpers.cs
index 3f06b3def7f29c..921f447bb6fcf4 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/RuntimeHelpers.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/RuntimeHelpers.cs
@@ -27,29 +27,40 @@ public static T[] GetSubArray<T>(T[] array, Range range)
 
             (int offset, int length) = range.GetOffsetAndLength(array.Length);
 
+            T[] dest;
+
             if (typeof(T).IsValueType || typeof(T[]) == array.GetType())
             {
-                // We know the type of the array to be exactly T[].
+                // We know the type of the array to be exactly T[] or an array variance
+                // compatible value type substitution like int[] <-> uint[].
 
                 if (length == 0)
                 {
                     return Array.Empty<T>();
                 }
 
-                var dest = new T[length];
-                Buffer.Memmove(
-                    ref MemoryMarshal.GetArrayDataReference(dest),
-                    ref Unsafe.Add(ref MemoryMarshal.GetArrayDataReference(array), offset),
-                    (uint)length);
-                return dest;
+                dest = new T[length];
             }
             else
             {
-                // The array is actually a U[] where U:T.
-                T[] dest = (T[])Array.CreateInstance(array.GetType().GetElementType()!, length);
-                Array.Copy(array, offset, dest, 0, length);
-                return dest;
+                // The array is actually a U[] where U:T. We'll make sure to create
+                // an array of the exact same backing type. The cast to T[] will
+                // never fail.
+
+                dest = Unsafe.As<T[]>(Array.CreateInstance(array.GetType().GetElementType()!, length));
             }
+
+            // In either case, the newly-allocated array is the exact same type as the
+            // original incoming array. It's safe for us to Buffer.Memmove the contents
+            // from the source array to the destination array, otherwise the contents
+            // wouldn't have been valid for the source array in the first place.
+
+            Buffer.Memmove(
+                ref MemoryMarshal.GetArrayDataReference(dest),
+                ref Unsafe.Add(ref MemoryMarshal.GetArrayDataReference(array), offset),
+                (uint)length);
+
+            return dest;
         }
 
         public static object GetUninitializedObject(Type type)