diff --git a/src/coreclr/tests/issues.targets b/src/coreclr/tests/issues.targets
index ce48665769cbde..fd3837e0148b17 100644
--- a/src/coreclr/tests/issues.targets
+++ b/src/coreclr/tests/issues.targets
@@ -11,6 +11,25 @@
         <ExcludeList Include="$(XunitTestBinBase)/Regressions/coreclr/GitHub_22888/test22888/*">
             <Issue>https://github.com/dotnet/runtime/issues/13703</Issue>
         </ExcludeList>
+        <!-- Test regressions during CI coverage outage -->
+        <ExcludeList Include="$(XunitTestBinBase)/baseservices/exceptions/stackoverflow/*">
+            <Issue>https://github.com/dotnet/runtime/issues/35798</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/SIMD/Vector3Interop_r/*">
+            <Issue>https://github.com/dotnet/runtime/issues/35798</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/SIMD/Vector3Interop_ro/*">
+            <Issue>https://github.com/dotnet/runtime/issues/35798</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/baseservices/typeequivalence/simple/Simple/*">
+            <Issue>https://github.com/dotnet/runtime/issues/35798</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/Interop/StructMarshalling/ReversePInvoke/MarshalSeqStruct/Reverse/*">
+            <Issue>https://github.com/dotnet/runtime/issues/35798</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/Interop/PInvoke/Vector2_3_4/Vector2_3_4/*">
+            <Issue>https://github.com/dotnet/runtime/issues/35798</Issue>
+        </ExcludeList>
     </ItemGroup>
 
     <!-- All OS/Arch CoreCLR excludes -->
@@ -1908,4 +1927,899 @@
 	</ExcludeList>
     </ItemGroup>
 
+    <!-- The following tests are marked with CLRTestTargetUnsupported
+
+         These used to not be built for specific targets.
+
+         To support building on all targets,  These are now built in CI, but should be excluded from
+         running on specific targets.
+
+         The CLRTestTargetUnsupported property was intended to conditionally disable running the tests,
+         but the implementation is incomplete.
+
+         Each test is disabled to make the new CI systme of building all tests for all target on OSX
+         work properly.
+
+         Some of these may be duplicates of above.
+    -->
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+    <!-- Only run on non Windows -->
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 </Project>
diff --git a/src/coreclr/tests/src/Interop/COM/ComWrappers/GlobalInstance/GlobalInstanceTrackerSupportTests.csproj b/src/coreclr/tests/src/Interop/COM/ComWrappers/GlobalInstance/GlobalInstanceTrackerSupportTests.csproj
index 4742bf4b547f3c..77b1ed75a64eb7 100644
--- a/src/coreclr/tests/src/Interop/COM/ComWrappers/GlobalInstance/GlobalInstanceTrackerSupportTests.csproj
+++ b/src/coreclr/tests/src/Interop/COM/ComWrappers/GlobalInstance/GlobalInstanceTrackerSupportTests.csproj
@@ -7,8 +7,7 @@
     <!-- Blocked on ILAsm supporting embedding resources. See https://github.com/dotnet/coreclr/issues/20819 -->
     <IlrtTestKind>BuildOnly</IlrtTestKind>
     <!-- Test unsupported outside of windows -->
-    <TestUnsupportedOutsideWindows>true</TestUnsupportedOutsideWindows>
-    <DisableProjectBuild Condition="'$(TargetsWindows)' != 'true'">true</DisableProjectBuild>
+    <CLRTestTargetUnsupported Condition="'$(TargetsWindows)' != 'true'">true</CLRTestTargetUnsupported>
     <!-- This test would require the runincontext.exe to include App.manifest describing the COM interfaces -->
     <UnloadabilityIncompatible>true</UnloadabilityIncompatible>
     <AllowUnsafeBlocks>true</AllowUnsafeBlocks>