diff --git a/src/mono/mono/mini/CMakeLists.txt b/src/mono/mono/mini/CMakeLists.txt
index 58b2e3767203f3..a18365f553545c 100644
--- a/src/mono/mono/mini/CMakeLists.txt
+++ b/src/mono/mono/mini/CMakeLists.txt
@@ -1,5 +1,7 @@
 project(mini)
 
+include(FindPython3)
+
 function(addprefix var prefix list)
   set(f)
   foreach(i ${list})
@@ -314,6 +316,8 @@ if(NOT DISABLE_SHARED_LIBS)
   install(TARGETS monosgen LIBRARY)
 endif()
 
+find_package(Python3 COMPONENTS Interpreter)
+
 # FIXME: Always rebuilds, creates non-deterministic builds
 # FIXME: Use the previous format
 #string(TIMESTAMP BUILD_DATE)
@@ -337,31 +341,31 @@ add_custom_command(
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-amd64.h
-  COMMAND python ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_AMD64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-amd64.h amd64_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-amd64.md
+  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_AMD64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-amd64.h amd64_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-amd64.md
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-x86.h
-  COMMAND python ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_X86 ${CMAKE_CURRENT_SOURCE_DIR} cpu-x86.h x86_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-x86.md
+  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_X86 ${CMAKE_CURRENT_SOURCE_DIR} cpu-x86.h x86_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-x86.md
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-arm64.h
-  COMMAND python ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm64.h arm64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm64.md
+  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm64.h arm64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm64.md
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-arm.h
-  COMMAND python ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm.h arm_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm.md
+  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm.h arm_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm.md
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-wasm.h
-  COMMAND python ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_WASM ${CMAKE_CURRENT_SOURCE_DIR} cpu-wasm.h wasm_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-wasm.md
+  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_WASM ${CMAKE_CURRENT_SOURCE_DIR} cpu-wasm.h wasm_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-wasm.md
   VERBATIM
 )