diff --git a/src/libraries/System.Data.Odbc/src/ILLink/ILLink.Suppressions.xml b/src/libraries/System.Data.Odbc/src/ILLink/ILLink.Suppressions.xml
index 533fc1cd0ed04d..0504df00e7659e 100644
--- a/src/libraries/System.Data.Odbc/src/ILLink/ILLink.Suppressions.xml
+++ b/src/libraries/System.Data.Odbc/src/ILLink/ILLink.Suppressions.xml
@@ -5,7 +5,7 @@
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:Interop.Odbc.SQLSetConnectAttrW(System.Data.Odbc.OdbcConnectionHandle,System.Data.Odbc.ODBC32.SQL_ATTR,System.Transactions.IDtcTransaction,System.Int32)</property>
+      <property name="Target">M:System.Data.Odbc.OdbcConnectionHandle.SetConnectionAttribute4(System.Data.Odbc.ODBC32.SQL_ATTR,System.Transactions.IDtcTransaction,System.Int32)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
diff --git a/src/libraries/System.Data.OleDb/src/ILLink/ILLink.Suppressions.xml b/src/libraries/System.Data.OleDb/src/ILLink/ILLink.Suppressions.xml
index 2e52a33c8a98ed..5386e4bd294fcc 100644
--- a/src/libraries/System.Data.OleDb/src/ILLink/ILLink.Suppressions.xml
+++ b/src/libraries/System.Data.OleDb/src/ILLink/ILLink.Suppressions.xml
@@ -5,7 +5,25 @@
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Data.Common.UnsafeNativeMethods.GetErrorInfo(System.Int32,System.Data.Common.UnsafeNativeMethods.IErrorInfo@)</property>
+      <property name="Target">M:System.Data.OleDb.DBPropSet.SetLastErrorInfo(System.Data.OleDb.OleDbHResult)</property>
+    </attribute>
+    <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
+      <argument>ILLink</argument>
+      <argument>IL2050</argument>
+      <property name="Scope">member</property>
+      <property name="Target">M:System.Data.OleDb.OleDbConnection.ProcessResults(System.Data.OleDb.OleDbHResult,System.Data.OleDb.OleDbConnection,System.Object)</property>
+    </attribute>
+    <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
+      <argument>ILLink</argument>
+      <argument>IL2050</argument>
+      <property name="Scope">member</property>
+      <property name="Target">M:System.Data.OleDb.OleDbDataAdapter.FillClose(System.Boolean,System.Object)</property>
+    </attribute>
+    <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
+      <argument>ILLink</argument>
+      <argument>IL2050</argument>
+      <property name="Scope">member</property>
+      <property name="Target">M:System.Data.OleDb.OleDbDataAdapter.FillFromADODB(System.Object,System.Object,System.String,System.Boolean)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
diff --git a/src/libraries/System.DirectoryServices.AccountManagement/src/ILLink/ILLink.Suppressions.xml b/src/libraries/System.DirectoryServices.AccountManagement/src/ILLink/ILLink.Suppressions.xml
index ae9db1185dd9c2..7572cc7074afbb 100644
--- a/src/libraries/System.DirectoryServices.AccountManagement/src/ILLink/ILLink.Suppressions.xml
+++ b/src/libraries/System.DirectoryServices.AccountManagement/src/ILLink/ILLink.Suppressions.xml
@@ -5,7 +5,7 @@
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.DirectoryServices.AccountManagement.UnsafeNativeMethods.IntADsOpenObject(System.String,System.String,System.String,System.Int32,System.Guid@,System.Object@)</property>
+      <property name="Target">M:System.DirectoryServices.AccountManagement.UnsafeNativeMethods.ADsOpenObject(System.String,System.String,System.String,System.Int32,System.Guid@,System.Object@)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
diff --git a/src/libraries/System.DirectoryServices/src/ILLink/ILLink.Suppressions.xml b/src/libraries/System.DirectoryServices/src/ILLink/ILLink.Suppressions.xml
index 0e87e736269c4d..ca9681a8e8f63b 100644
--- a/src/libraries/System.DirectoryServices/src/ILLink/ILLink.Suppressions.xml
+++ b/src/libraries/System.DirectoryServices/src/ILLink/ILLink.Suppressions.xml
@@ -5,7 +5,7 @@
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.DirectoryServices.Interop.UnsafeNativeMethods.IntADsOpenObject(System.String,System.String,System.String,System.Int32,System.Guid@,System.Object@)</property>
+      <property name="Target">M:System.DirectoryServices.Interop.UnsafeNativeMethods.ADsOpenObject(System.String,System.String,System.String,System.Int32,System.Guid@,System.Object@)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
diff --git a/src/libraries/System.Drawing.Common/src/ILLink/ILLink.Suppressions.xml b/src/libraries/System.Drawing.Common/src/ILLink/ILLink.Suppressions.xml
index d19184f1f2224b..0e1700f4a61159 100644
--- a/src/libraries/System.Drawing.Common/src/ILLink/ILLink.Suppressions.xml
+++ b/src/libraries/System.Drawing.Common/src/ILLink/ILLink.Suppressions.xml
@@ -53,67 +53,61 @@
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.Icon.OleCreatePictureIndirect(System.Drawing.Icon.PICTDESC,System.Guid@,System.Boolean)</property>
+      <property name="Target">M:System.Drawing.Bitmap.#ctor(System.IO.Stream,System.Boolean)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipCreateBitmapFromStream(Interop.Ole32.IStream,System.IntPtr@)</property>
+      <property name="Target">M:System.Drawing.Icon.Save(System.IO.Stream)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipCreateBitmapFromStreamICM(Interop.Ole32.IStream,System.IntPtr@)</property>
+      <property name="Target">M:System.Drawing.Image.FromStream(System.IO.Stream,System.Boolean,System.Boolean)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipCreateMetafileFromStream(Interop.Ole32.IStream,System.IntPtr@)</property>
+      <property name="Target">M:System.Drawing.Image.InitializeFromStream(System.IO.Stream)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipGetMetafileHeaderFromStream(Interop.Ole32.IStream,System.IntPtr)</property>
+      <property name="Target">M:System.Drawing.Image.Save(System.IO.Stream,System.Drawing.Imaging.ImageCodecInfo,System.Drawing.Imaging.EncoderParameters)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipLoadImageFromStream(Interop.Ole32.IStream,System.IntPtr@)</property>
+      <property name="Target">M:System.Drawing.Imaging.Metafile.#ctor(System.IO.Stream,System.IntPtr,System.Drawing.Imaging.EmfType,System.String)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipLoadImageFromStreamICM(Interop.Ole32.IStream,System.IntPtr@)</property>
+      <property name="Target">M:System.Drawing.Imaging.Metafile.#ctor(System.IO.Stream,System.IntPtr,System.Drawing.Rectangle,System.Drawing.Imaging.MetafileFrameUnit,System.Drawing.Imaging.EmfType,System.String)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipRecordMetafileStream(Interop.Ole32.IStream,System.IntPtr,System.Drawing.Imaging.EmfType,System.Drawing.RectangleF@,System.Drawing.Imaging.MetafileFrameUnit,System.String,System.IntPtr@)</property>
+      <property name="Target">M:System.Drawing.Imaging.Metafile.#ctor(System.IO.Stream,System.IntPtr,System.Drawing.RectangleF,System.Drawing.Imaging.MetafileFrameUnit,System.Drawing.Imaging.EmfType,System.String)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipRecordMetafileStream(Interop.Ole32.IStream,System.IntPtr,System.Drawing.Imaging.EmfType,System.IntPtr,System.Drawing.Imaging.MetafileFrameUnit,System.String,System.IntPtr@)</property>
+      <property name="Target">M:System.Drawing.Imaging.Metafile.#ctor(System.IO.Stream)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>
       <argument>IL2050</argument>
       <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipRecordMetafileStreamI(Interop.Ole32.IStream,System.IntPtr,System.Drawing.Imaging.EmfType,System.Drawing.Rectangle@,System.Drawing.Imaging.MetafileFrameUnit,System.String,System.IntPtr@)</property>
-    </attribute>
-    <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
-      <argument>ILLink</argument>
-      <argument>IL2050</argument>
-      <property name="Scope">member</property>
-      <property name="Target">M:System.Drawing.SafeNativeMethods.Gdip.GdipSaveImageToStream(System.Runtime.InteropServices.HandleRef,Interop.Ole32.IStream,System.Guid@,System.Runtime.InteropServices.HandleRef)</property>
+      <property name="Target">M:System.Drawing.Imaging.Metafile.GetMetafileHeader(System.IO.Stream)</property>
     </attribute>
     <attribute fullname="System.Diagnostics.CodeAnalysis.UnconditionalSuppressMessageAttribute">
       <argument>ILLink</argument>