diff --git a/eng/native/configurecompiler.cmake b/eng/native/configurecompiler.cmake
index 3e819071f6111c..16478c1f12e03d 100644
--- a/eng/native/configurecompiler.cmake
+++ b/eng/native/configurecompiler.cmake
@@ -390,6 +390,8 @@ if (CLR_CMAKE_HOST_UNIX)
     # to a struct or a class that has virtual members or a base class. In that case, clang
     # may not generate the same object layout as MSVC.
     add_compile_options(-Wno-incompatible-ms-struct)
+
+    add_compile_options(-Wno-reserved-identifier)
   else()
     add_compile_options(-Wno-unused-but-set-variable)
     add_compile_options(-Wno-uninitialized)
diff --git a/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c b/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c
index f0273afac9fa6c..b3c2d6f95de957 100644
--- a/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c
+++ b/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c
@@ -815,6 +815,7 @@ static int32_t GetSearchIteratorUsingCollator(
     if (!U_SUCCESS(err))
     {
         int32_t r;
+        (void)r; // used only in assert
         r = RestoreSearchHandle(pSortHandle, *pSearchIterator, options);
         assert(r && "restoring search handle shouldn't fail.");
         return -1;
@@ -824,6 +825,7 @@ static int32_t GetSearchIteratorUsingCollator(
     if (!U_SUCCESS(err))
     {
         int32_t r;
+        (void)r; // used only in assert
         r = RestoreSearchHandle(pSortHandle, *pSearchIterator, options);
         assert(r && "restoring search handle shouldn't fail.");
         return -1;
diff --git a/src/libraries/Native/Unix/System.Native/pal_process.c b/src/libraries/Native/Unix/System.Native/pal_process.c
index 5e97d958f74d17..fabdfae76187ca 100644
--- a/src/libraries/Native/Unix/System.Native/pal_process.c
+++ b/src/libraries/Native/Unix/System.Native/pal_process.c
@@ -191,6 +191,24 @@ static int SetGroups(uint32_t* userGroups, int32_t userGroupsLength, uint32_t* p
     return rv;
 }
 
+typedef void (*VoidIntFn)(int);
+
+static
+VoidIntFn
+handler_from_sigaction (struct sigaction *sa)
+{
+    if (((unsigned int)sa->sa_flags) & SA_SIGINFO)
+    {
+        // work around -Wcast-function-type
+        void (*tmp)(void) = (void (*)(void))sa->sa_sigaction;
+        return (void (*)(int))tmp;
+    }
+    else
+    {
+        return sa->sa_handler;
+    }
+}
+
 int32_t SystemNative_ForkAndExecProcess(const char* filename,
                                       char* const argv[],
                                       char* const envp[],
@@ -371,7 +389,7 @@ int32_t SystemNative_ForkAndExecProcess(const char* filename,
             }
             if (!sigaction(sig, NULL, &sa_old))
             {
-                void (*oldhandler)(int) = (((unsigned int)sa_old.sa_flags) & SA_SIGINFO) ? (void (*)(int))sa_old.sa_sigaction : sa_old.sa_handler;
+                void (*oldhandler)(int) = handler_from_sigaction (&sa_old);
                 if (oldhandler != SIG_IGN && oldhandler != SIG_DFL)
                 {
                     // It has a custom handler, put the default handler back.
diff --git a/src/libraries/Native/Unix/System.Native/pal_signal.c b/src/libraries/Native/Unix/System.Native/pal_signal.c
index 6e7243fca17eee..39ed43f092f3fe 100644
--- a/src/libraries/Native/Unix/System.Native/pal_signal.c
+++ b/src/libraries/Native/Unix/System.Native/pal_signal.c
@@ -627,6 +627,7 @@ void SystemNative_DisablePosixSignalHandling(int signalCode)
 void InstallTTOUHandlerForConsole(ConsoleSigTtouHandler handler)
 {
     bool installed;
+    (void)installed; // used only for assert
 
     pthread_mutex_lock(&lock);
     {
diff --git a/src/libraries/Native/Unix/System.Security.Cryptography.Native/openssl.c b/src/libraries/Native/Unix/System.Security.Cryptography.Native/openssl.c
index c18eb0ffb7c6bb..2de6635a036e07 100644
--- a/src/libraries/Native/Unix/System.Security.Cryptography.Native/openssl.c
+++ b/src/libraries/Native/Unix/System.Security.Cryptography.Native/openssl.c
@@ -1289,6 +1289,7 @@ static void HandleShutdown()
     // ensures that there are no callers already inside the string table
     // when the unload (possibly) executes.
     int result = pthread_mutex_lock(&g_err_mutex);
+    (void)result; // used only in assert
     assert(!result && "Acquiring the error string table mutex failed.");
 
     g_err_unloaded = 1;
diff --git a/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_err.c b/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_err.c
index e1ca3292fbab2e..0dc9813138d6d2 100644
--- a/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_err.c
+++ b/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_err.c
@@ -37,6 +37,7 @@ const char* CryptoNative_ErrReasonErrorString(uint64_t error)
 
 #if defined NEED_OPENSSL_1_1 || defined NEED_OPENSSL_3_0
     int result = pthread_mutex_lock(&g_err_mutex);
+    (void)result; // used only in assert
     assert(!result && "Acquiring the error string table mutex failed.");
 
     if (!g_err_unloaded)
@@ -57,6 +58,7 @@ void CryptoNative_ErrErrorStringN(uint64_t e, char* buf, int32_t len)
 {
 #if defined NEED_OPENSSL_1_1 || defined NEED_OPENSSL_3_0
     int result = pthread_mutex_lock(&g_err_mutex);
+    (void)result; // used only in assert
     assert(!result && "Acquiring the error string table mutex failed.");
 
     if (!g_err_unloaded)
diff --git a/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_ssl.c b/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_ssl.c
index 2b4eb271b022a2..7139a3a62388a2 100644
--- a/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_ssl.c
+++ b/src/libraries/Native/Unix/System.Security.Cryptography.Native/pal_ssl.c
@@ -75,6 +75,7 @@ static void DetectCiphersuiteConfiguration()
     SSL_free(ssl);
 
     int rv = SSL_CTX_set_cipher_list(ctx, "ALL");
+    (void)rv; // used only in assert
     assert(rv);
 
     ssl = SSL_new(ctx);