diff --git a/docs/releases/upcoming/190.removal.rst b/docs/releases/upcoming/190.removal.rst
new file mode 100644
index 000000000..c0247c4db
--- /dev/null
+++ b/docs/releases/upcoming/190.removal.rst
@@ -0,0 +1 @@
+Remove support for Python 2.7 and 3.5 (#190)
\ No newline at end of file
diff --git a/etstool.py b/etstool.py
index c5ffde2ed..21367a9d4 100644
--- a/etstool.py
+++ b/etstool.py
@@ -53,7 +53,7 @@
 
     python etstool.py test_all
 
-Currently supported runtime values are ``2.7``, ``3.5``, ``3.6``.  Not all
+Currently supported runtime value is``3.6``.  Not all
 runtimes will work, but the tasks will fail with a clear error if that is the
 case.
 
@@ -95,8 +95,6 @@
 DEFAULT_RUNTIME = "3.6"
 
 supported_runtimes = [
-    '2.7',
-    '3.5',
     '3.6',
 ]
 
diff --git a/setup.py b/setup.py
index 050e37228..669c0f6a6 100644
--- a/setup.py
+++ b/setup.py
@@ -138,4 +138,5 @@ def write_version_py(filename='apptools/_version.py'):
           packages=find_packages(),
           platforms=["Windows", "Linux", "Mac OS-X", "Unix", "Solaris"],
           zip_safe=False,
-          )
+          python_requires=">=3.6",
+    )