diff --git a/packages/react/src/ReactHooks.js b/packages/react/src/ReactHooks.js
index 3e28896f2bb8..8acaddb88433 100644
--- a/packages/react/src/ReactHooks.js
+++ b/packages/react/src/ReactHooks.js
@@ -96,6 +96,14 @@ export function useEffect(
   inputs: Array<mixed> | void | null,
 ) {
   const dispatcher = resolveDispatcher();
+
+  if (__DEV__) {
+    invariant(
+      create != null,
+      'useEffect must be called with a create function, but null or undefined was passed.',
+    );
+  }
+
   return dispatcher.useEffect(create, inputs);
 }
 
@@ -104,6 +112,14 @@ export function useLayoutEffect(
   inputs: Array<mixed> | void | null,
 ) {
   const dispatcher = resolveDispatcher();
+
+  if (__DEV__) {
+    invariant(
+      create != null,
+      'useLayoutEffect must be called with a create function, but null or undefined was passed.',
+    );
+  }
+
   return dispatcher.useLayoutEffect(create, inputs);
 }