diff --git a/src/transformers/utils/chat_parsing_utils.py b/src/transformers/utils/chat_parsing_utils.py
index d1ab2791c3f7..1035d65b094a 100644
--- a/src/transformers/utils/chat_parsing_utils.py
+++ b/src/transformers/utils/chat_parsing_utils.py
@@ -70,14 +70,22 @@ def recursive_parse(
 
     # If not, we have to do a little parsing. First, set some vars and do basic validation
     node_type = node_schema.get("type")
-    has_regex = "x-regex" in node_schema or "x-regex-iterator" in node_schema or "x-regex-key-value" in node_schema
+    has_regex = (
+        "x-regex" in node_schema
+        or "x-regex-iterator" in node_schema
+        or "x-regex-key-value" in node_schema
+        or "x-regex-substitutions" in node_schema
+    )
     if has_regex and not isinstance(node_content, str):
         raise TypeError(
-            "Schema node got a non-string input, but has a regex for parsing.\n"
+            "Schema node got a non-string input, but has a regex for parsing or substitution.\n"
             f"Input: {node_content}\n"
             f"Schema: {node_schema}"
         )
 
+    node_subs = node_schema.get("x-regex-substitutions", [])
+    for node_sub in node_subs:
+        node_content = re.sub(node_sub[0], node_sub[1], node_content, flags=re.DOTALL)
     node_regex = node_schema.get("x-regex")
     node_regex_iterator = node_schema.get("x-regex-iterator")
     node_regex_to_dict = node_schema.get("x-regex-key-value")
diff --git a/tests/utils/test_chat_parsing_utils.py b/tests/utils/test_chat_parsing_utils.py
index 6f91f9a2d97b..60bc181d1c88 100644
--- a/tests/utils/test_chat_parsing_utils.py
+++ b/tests/utils/test_chat_parsing_utils.py
@@ -180,6 +180,42 @@
     },
 }
 
+re_sub_schema = {
+    "type": "object",
+    "properties": {
+        "role": {"const": "assistant"},
+        "thinking": {"type": "string"},
+        "content": {"type": "string"},
+        "tool_calls": {
+            "x-regex-iterator": r"<\|tool_call>(.*?)<tool_call\|>",
+            "type": "array",
+            "items": {
+                "type": "object",
+                "properties": {
+                    "type": {"const": "function"},
+                    "function": {
+                        "type": "object",
+                        "x-regex": r"call\:(?P<name>\w+)(?P<arguments>\{.*\})",
+                        "properties": {
+                            "name": {
+                                "type": "string",
+                            },
+                            "arguments": {
+                                "type": "object",
+                                "x-regex-key-value": r'(?P<key>\w+):(?P<value><\|"\|>.*?<\|"\|>|[^,}]+)',
+                                "additionalProperties": {
+                                    "x-regex-substitutions": [[r'^<\|"\|>|<\|"\|>$', ""]],
+                                },
+                            },
+                        },
+                    },
+                },
+            },
+        },
+    },
+    "x-regex": r"(\<\|channel\>thought\n(?P<thinking>.*?)\<channel\|\>)?(?P<content>(?:(?!\<\|tool_call\>).)+)?(?P<tool_calls>\<\|tool_call\>.*\<tool_call\|\>)?",
+}
+
 prefix_items_schema = {
     # Not intended to be "realistic", just checks that prefixItems can handle a heterogeneous array
     "x-regex-iterator": r"<block>(.*?)<\/block>",
@@ -389,6 +425,27 @@ def test_qwen3_tool_calls(self):
             },
         )
 
+    def test_re_sub_schema(self):
+        """Test that a schema doing re substitutions to enable JSON parsing works."""
+        model_out = '<|channel>thought\nThe user is asking for the current temperature in Paris. I should check the available tools to see if there\'s a function that can provide this information.<channel|><|tool_call>call:get_current_temperature{detail_level:0,location:<|"|>Paris, France<|"|>,unit:<|"|>celsius<|"|>}<tool_call|><|tool_response>'
+        parsed = recursive_parse(model_out, re_sub_schema)
+        self.assertEqual(
+            parsed,
+            {
+                "role": "assistant",
+                "thinking": "The user is asking for the current temperature in Paris. I should check the available tools to see if there's a function that can provide this information.",
+                "tool_calls": [
+                    {
+                        "type": "function",
+                        "function": {
+                            "name": "get_current_temperature",
+                            "arguments": {"detail_level": "0", "location": "Paris, France", "unit": "celsius"},
+                        },
+                    }
+                ],
+            },
+        )
+
     def test_required_fields_present(self):
         """Test that required fields pass validation when present in the output."""
         schema = {