diff --git a/core/src/components/toast/test/a11y/index.html b/core/src/components/toast/test/a11y/index.html
index 9e8b0c63510..b2eb88a7ae1 100644
--- a/core/src/components/toast/test/a11y/index.html
+++ b/core/src/components/toast/test/a11y/index.html
@@ -18,21 +18,47 @@
       <main>
         <h1 style="background-color: white">Toast - a11y</h1>
 
-        <button id="polite" onclick="presentToast({ message: 'This is a toast message' })">Present Toast</button>
-        <button
-          id="assertive"
-          onclick="presentToast({ message: 'This is an assertive toast message', htmlAttributes: { 'aria-live': 'assertive' } })"
+        <ion-button id="inline-toast-trigger">Present Inline Toast</ion-button>
+        <ion-toast
+          id="inline-toast"
+          trigger="inline-toast-trigger"
+          icon="person"
+          header="Inline Toast Header"
+          message="Inline Toast Message"
+        ></ion-toast>
+
+        <ion-button
+          id="controller-toast-trigger"
+          onclick="presentToast({ icon: 'person', header: 'Controller Toast Header', message: 'Controller Toast Message', buttons: ['Ok'] })"
         >
-          Present Assertive Toast
-        </button>
+          Present Controller Toast
+        </ion-button>
+
+        <ion-button onclick="updateContent()">Update Inner Content</ion-button>
       </main>
     </ion-app>
     <script>
+      const inlineToast = document.querySelector('#inline-toast');
+      inlineToast.buttons = ['Ok'];
+
       const presentToast = async (opts) => {
         const toast = await toastController.create(opts);
 
         await toast.present();
       };
+
+      const updateContent = () => {
+        const toasts = document.querySelectorAll('ion-toast');
+        /**
+         * Note: Multiple updates to the props
+         * may cause screen readers like NVDA to announce
+         * the entire content multiple times.
+         */
+        toasts.forEach((toast) => {
+          toast.header = 'Updated Header';
+          toast.message = 'Updated Message';
+        });
+      };
     </script>
   </body>
 </html>
diff --git a/core/src/components/toast/test/a11y/toast.e2e.ts b/core/src/components/toast/test/a11y/toast.e2e.ts
index 9b98496ef2a..a9ccf76cba0 100644
--- a/core/src/components/toast/test/a11y/toast.e2e.ts
+++ b/core/src/components/toast/test/a11y/toast.e2e.ts
@@ -7,12 +7,10 @@ test.describe('toast: a11y', () => {
     test.skip(testInfo.project.metadata.rtl === true, 'This test does not check LTR vs RTL layouts');
     await page.goto(`/src/components/toast/test/a11y`);
   });
-  test('should not have any axe violations with polite toasts', async ({ page }) => {
+  test('should not have any axe violations with inline toasts', async ({ page }) => {
     const ionToastDidPresent = await page.spyOnEvent('ionToastDidPresent');
 
-    const politeButton = page.locator('#polite');
-    await politeButton.click();
-
+    await page.click('#inline-toast-trigger');
     await ionToastDidPresent.next();
 
     /**
@@ -23,12 +21,10 @@ test.describe('toast: a11y', () => {
     const results = await new AxeBuilder({ page }).disableRules('color-contrast').analyze();
     expect(results.violations).toEqual([]);
   });
-  test('should not have any axe violations with assertive toasts', async ({ page }) => {
+  test('should not have any axe violations with controller toasts', async ({ page }) => {
     const ionToastDidPresent = await page.spyOnEvent('ionToastDidPresent');
 
-    const politeButton = page.locator('#assertive');
-    await politeButton.click();
-
+    await page.click('#controller-toast-trigger');
     await ionToastDidPresent.next();
 
     /**
diff --git a/core/src/components/toast/test/toast.spec.ts b/core/src/components/toast/test/toast.spec.ts
index 1f25432e547..711b08e549f 100644
--- a/core/src/components/toast/test/toast.spec.ts
+++ b/core/src/components/toast/test/toast.spec.ts
@@ -2,7 +2,7 @@ import { newSpecPage } from '@stencil/core/testing';
 import { Toast } from '../toast';
 import { config } from '../../../global/config';
 
-describe('alert: custom html', () => {
+describe('toast: custom html', () => {
   it('should not allow for custom html by default', async () => {
     const page = await newSpecPage({
       components: [Toast],
@@ -41,3 +41,50 @@ describe('alert: custom html', () => {
     expect(content.querySelector('button.custom-html')).toBe(null);
   });
 });
+
+/**
+ * These tests check if the aria-hidden attributes are being
+ * removed on present. Without this functionality, screen readers
+ * would not announce toast content correctly.
+ */
+describe('toast: a11y smoke test', () => {
+  it('should have aria-hidden content when dismissed', async () => {
+    const page = await newSpecPage({
+      components: [Toast],
+      html: `<ion-toast message="Message" header="Header"></ion-toast>`,
+    });
+
+    const toast = page.body.querySelector('ion-toast');
+    const header = toast.shadowRoot.querySelector('.toast-header');
+    const message = toast.shadowRoot.querySelector('.toast-message');
+
+    expect(header.getAttribute('aria-hidden')).toBe('true');
+    expect(message.getAttribute('aria-hidden')).toBe('true');
+  });
+
+  it('should not have aria-hidden content when presented', async () => {
+    const page = await newSpecPage({
+      components: [Toast],
+      html: `
+        <ion-app>
+          <ion-toast animated="false" message="Message" header="Header"></ion-toast>
+        </ion-app>
+      `,
+    });
+
+    const toast = page.body.querySelector('ion-toast');
+
+    /**
+     * Wait for present method to resolve
+     * and for state change to take effect.
+     */
+    await toast.present();
+    await page.waitForChanges();
+
+    const header = toast.shadowRoot.querySelector('.toast-header');
+    const message = toast.shadowRoot.querySelector('.toast-message');
+
+    expect(header.getAttribute('aria-hidden')).toBe(null);
+    expect(message.getAttribute('aria-hidden')).toBe(null);
+  });
+});
diff --git a/core/src/components/toast/toast.tsx b/core/src/components/toast/toast.tsx
index 64dc0060eac..9c2f01ce9df 100644
--- a/core/src/components/toast/toast.tsx
+++ b/core/src/components/toast/toast.tsx
@@ -1,5 +1,5 @@
 import type { ComponentInterface, EventEmitter } from '@stencil/core';
-import { Watch, Component, Element, Event, h, Host, Method, Prop } from '@stencil/core';
+import { Watch, Component, Element, Event, h, Host, Method, Prop, State } from '@stencil/core';
 
 import { config } from '../../global/config';
 import { getIonMode } from '../../global/ionic-global';
@@ -55,6 +55,13 @@ export class Toast implements ComponentInterface, OverlayInterface {
 
   presented = false;
 
+  /**
+   * When `true`, content inside of .toast-content
+   * will have aria-hidden elements removed causing
+   * screen readers to announce the remaining content.
+   */
+  @State() revealContentToScreenReader = false;
+
   @Element() el!: HTMLIonToastElement;
 
   /**
@@ -268,6 +275,14 @@ export class Toast implements ComponentInterface, OverlayInterface {
       this.position
     );
     await this.currentTransition;
+
+    /**
+     * Content is revealed to screen readers after
+     * the transition to avoid jank since this
+     * state updates will cause a re-render.
+     */
+    this.revealContentToScreenReader = true;
+
     this.currentTransition = undefined;
 
     if (this.duration > 0) {
@@ -303,6 +318,7 @@ export class Toast implements ComponentInterface, OverlayInterface {
 
     if (dismissed) {
       this.delegateController.removeViewFromDom();
+      this.revealContentToScreenReader = false;
     }
 
     return dismissed;
@@ -407,21 +423,47 @@ export class Toast implements ComponentInterface, OverlayInterface {
     );
   }
 
-  private renderToastMessage() {
+  /**
+   * Render the `message` property.
+   * @param key - A key to give the element a stable identity. This is used to improve compatibility with screen readers.
+   * @param ariaHidden - If "true" then content will be hidden from screen readers.
+   */
+  private renderToastMessage(key: string, ariaHidden: 'true' | null = null) {
     const { customHTMLEnabled, message } = this;
     if (customHTMLEnabled) {
-      return <div class="toast-message" part="message" innerHTML={sanitizeDOMString(message)}></div>;
+      return (
+        <div
+          key={key}
+          aria-hidden={ariaHidden}
+          class="toast-message"
+          part="message"
+          innerHTML={sanitizeDOMString(message)}
+        ></div>
+      );
     }
 
     return (
-      <div class="toast-message" part="message">
+      <div key={key} aria-hidden={ariaHidden} class="toast-message" part="message">
         {message}
       </div>
     );
   }
 
+  /**
+   * Render the `header` property.
+   * @param key - A key to give the element a stable identity. This is used to improve compatibility with screen readers.
+   * @param ariaHidden - If "true" then content will be hidden from screen readers.
+   */
+  private renderHeader(key: string, ariaHidden: 'true' | null = null) {
+    return (
+      <div key={key} class="toast-header" aria-hidden={ariaHidden} part="header">
+        {this.header}
+      </div>
+    );
+  }
+
   render() {
-    const { layout, el } = this;
+    const { layout, el, revealContentToScreenReader, header, message } = this;
     const allButtons = this.getButtons();
     const startButtons = allButtons.filter((b) => b.side === 'start');
     const endButtons = allButtons.filter((b) => b.side !== 'start');
@@ -431,7 +473,6 @@ export class Toast implements ComponentInterface, OverlayInterface {
       [`toast-${this.position}`]: true,
       [`toast-layout-${layout}`]: true,
     };
-    const role = allButtons.length > 0 ? 'dialog' : 'status';
 
     /**
      * Stacked buttons are only meant to be
@@ -446,9 +487,6 @@ export class Toast implements ComponentInterface, OverlayInterface {
 
     return (
       <Host
-        aria-live="polite"
-        aria-atomic="true"
-        role={role}
         tabindex="-1"
         {...(this.htmlAttributes as any)}
         style={{
@@ -470,13 +508,40 @@ export class Toast implements ComponentInterface, OverlayInterface {
               <ion-icon class="toast-icon" part="icon" icon={this.icon} lazy={false} aria-hidden="true"></ion-icon>
             )}
 
-            <div class="toast-content">
-              {this.header !== undefined && (
-                <div class="toast-header" part="header">
-                  {this.header}
-                </div>
-              )}
-              {this.message !== undefined && this.renderToastMessage()}
+            {/*
+              This creates a live region where screen readers
+              only announce the header and the message. Elements
+              such as icons and buttons should not be announced.
+              aria-live and aria-atomic here are redundant, but we
+              add them to maximize browser compatibility.
+
+              Toasts are meant to be subtle notifications that do
+              not interrupt the user which is why this has
+              a "status" role and a "polite" presentation.
+            */}
+            <div class="toast-content" role="status" aria-atomic="true" aria-live="polite">
+              {/*
+                This logic below is done to improve consistency
+                across platforms when showing and updating live regions.
+
+                TalkBack and VoiceOver announce the live region content
+                when the toast is shown, but NVDA does not. As a result,
+                we need to trigger a DOM update so NVDA detects changes and
+                announces an update to the live region. We do this after
+                the toast is fully visible to avoid jank during the presenting
+                animation.
+
+                The "key" attribute is used here to force Stencil to render
+                new nodes and not re-use nodes. Otherwise, NVDA would not
+                detect any changes to the live region.
+
+                The "old" content is hidden using aria-hidden otherwise
+                VoiceOver will announce the toast content twice when presenting.
+              */}
+              {!revealContentToScreenReader && header !== undefined && this.renderHeader('oldHeader', 'true')}
+              {!revealContentToScreenReader && message !== undefined && this.renderToastMessage('oldMessage', 'true')}
+              {revealContentToScreenReader && header !== undefined && this.renderHeader('header')}
+              {revealContentToScreenReader && message !== undefined && this.renderToastMessage('header')}
             </div>
 
             {this.renderButtons(endButtons, 'end')}