diff --git a/change/@fluentui-react-native-menu-7499cad3-b53d-4e65-ac30-498b5e81638c.json b/change/@fluentui-react-native-menu-7499cad3-b53d-4e65-ac30-498b5e81638c.json
new file mode 100644
index 0000000000..3235315618
--- /dev/null
+++ b/change/@fluentui-react-native-menu-7499cad3-b53d-4e65-ac30-498b5e81638c.json
@@ -0,0 +1,7 @@
+{
+  "type": "patch",
+  "comment": "Fix for keyboard focus is lost when hovering out of a menu",
+  "packageName": "@fluentui-react-native/menu",
+  "email": "email not defined",
+  "dependentChangeType": "patch"
+}
diff --git a/packages/components/Menu/src/MenuList/MenuList.tsx b/packages/components/Menu/src/MenuList/MenuList.tsx
index d026b077f6..06039dd4ab 100644
--- a/packages/components/Menu/src/MenuList/MenuList.tsx
+++ b/packages/components/Menu/src/MenuList/MenuList.tsx
@@ -52,9 +52,12 @@ export const MenuList = compose<MenuListType>({
     const Slots = useSlots(menuList.props, (layer) => menuListLookup(layer, menuList, userProps));
 
     const focusZoneRef = React.useRef<View>();
+    const setFocusZoneFocus = () => {
+      focusZoneRef?.current?.focus();
+    };
 
     React.useEffect(() => {
-      focusZoneRef?.current?.focus();
+      setFocusZoneFocus();
     }, []);
 
     return (_final: MenuListProps, children: React.ReactNode) => {
@@ -83,7 +86,7 @@ export const MenuList = compose<MenuListType>({
 
       const content =
         Platform.OS === 'macos' ? (
-          <Slots.root>
+          <Slots.root onMouseLeave={setFocusZoneFocus}>
             <Slots.scrollView
               accessibilityRole="menu"
               showsVerticalScrollIndicator={menuContext.hasMaxHeight}