diff --git a/change/react-native-windows-d66c1eef-4346-43c7-8451-78ebe39f062b.json b/change/react-native-windows-d66c1eef-4346-43c7-8451-78ebe39f062b.json
new file mode 100644
index 00000000000..1ed9a328860
--- /dev/null
+++ b/change/react-native-windows-d66c1eef-4346-43c7-8451-78ebe39f062b.json
@@ -0,0 +1,7 @@
+{
+ "type": "prerelease",
+ "comment": "Default IncludeFabricInterface to true",
+ "packageName": "react-native-windows",
+ "email": "julio.rocha@microsoft.com",
+ "dependentChangeType": "patch"
+}
diff --git a/vnext/Desktop/React.Windows.Desktop.vcxproj b/vnext/Desktop/React.Windows.Desktop.vcxproj
index 8113a8d3dd5..e2fd63b7a4d 100644
--- a/vnext/Desktop/React.Windows.Desktop.vcxproj
+++ b/vnext/Desktop/React.Windows.Desktop.vcxproj
@@ -52,6 +52,7 @@
true
win32
false
+ true
true
diff --git a/vnext/ExperimentalFeatures.props b/vnext/ExperimentalFeatures.props
index 57a4b5aa3b9..bccc529f771 100644
--- a/vnext/ExperimentalFeatures.props
+++ b/vnext/ExperimentalFeatures.props
@@ -4,7 +4,6 @@
false
- true
true