diff --git a/src/Platform/Microsoft.Testing.Extensions.VSTestBridge/SynchronizedSingleSessionVSTestAndTestAnywhereAdapter.cs b/src/Platform/Microsoft.Testing.Extensions.VSTestBridge/SynchronizedSingleSessionVSTestAndTestAnywhereAdapter.cs
index 0789698909..e2d903229e 100644
--- a/src/Platform/Microsoft.Testing.Extensions.VSTestBridge/SynchronizedSingleSessionVSTestAndTestAnywhereAdapter.cs
+++ b/src/Platform/Microsoft.Testing.Extensions.VSTestBridge/SynchronizedSingleSessionVSTestAndTestAnywhereAdapter.cs
@@ -150,7 +150,7 @@ protected sealed override Task ExecuteRequestAsync(TestExecutionRequest request,
         => ExecuteRequestWithRequestCountGuardAsync(async () =>
         {
 #pragma warning disable IL3000 // Avoid accessing Assembly file path when publishing as a single file
-            string[] testAssemblyPaths = [.. _getTestAssemblies().Select(x => x.Location)];
+            string[] testAssemblyPaths = [.. _getTestAssemblies().Select(GetAssemblyPath)];
 #pragma warning restore IL3000 // Avoid accessing Assembly file path when publishing as a single file
             switch (request)
             {
@@ -179,6 +179,33 @@ public void Dispose()
         GC.SuppressFinalize(this);
     }
 
+    /// <summary>
+    /// Gets the path of an assembly, falling back to the assembly name when
+    /// <see cref="Assembly.Location"/> returns an empty string (e.g. on Android CoreCLR
+    /// where assemblies are memory-mapped).
+    /// </summary>
+#pragma warning disable IL3000 // Avoid accessing Assembly file path when publishing as a single file
+    internal static string GetAssemblyPath(Assembly assembly)
+    {
+#pragma warning disable IL3000 // Avoid accessing Assembly file path when publishing as a single file
+        string location = assembly.Location;
+#pragma warning restore IL3000 // Avoid accessing Assembly file path when publishing as a single file
+        if (!string.IsNullOrEmpty(location))
+        {
+            return location;
+        }
+
+        // On platforms like Android CoreCLR, assemblies may be memory-mapped and
+        // Assembly.Location returns an empty string. Use the assembly name as a
+        // synthetic path since the downstream code (on .NET Core) loads assemblies
+        // by name via Assembly.Load, not by file path.
+        string name = assembly.GetName().Name
+            ?? throw new InvalidOperationException($"Cannot determine the name of assembly '{assembly}'.");
+
+        return name + ".dll";
+    }
+#pragma warning restore IL3000 // Avoid accessing Assembly file path when publishing as a single file
+
     private async Task ExecuteRequestWithRequestCountGuardAsync(Func<Task> asyncFunc)
     {
         _incomingRequestCounter.AddCount();
diff --git a/test/UnitTests/Microsoft.Testing.Extensions.VSTestBridge.UnitTests/SynchronizedSingleSessionVSTestBridgedTestFrameworkTests.cs b/test/UnitTests/Microsoft.Testing.Extensions.VSTestBridge.UnitTests/SynchronizedSingleSessionVSTestBridgedTestFrameworkTests.cs
new file mode 100644
index 0000000000..ec336f40d8
--- /dev/null
+++ b/test/UnitTests/Microsoft.Testing.Extensions.VSTestBridge.UnitTests/SynchronizedSingleSessionVSTestBridgedTestFrameworkTests.cs
@@ -0,0 +1,105 @@
+// Copyright (c) Microsoft Corporation. All rights reserved.
+// Licensed under the MIT license. See LICENSE file in the project root for full license information.
+
+using System.Reflection;
+using System.Reflection.Emit;
+
+using Moq;
+
+namespace Microsoft.Testing.Extensions.VSTestBridge.UnitTests;
+
+[TestClass]
+public sealed class SynchronizedSingleSessionVSTestBridgedTestFrameworkTests
+{
+#if NETCOREAPP
+    [TestMethod]
+    public void GetAssemblyPath_WhenLocationIsNonEmpty_ReturnsLocation()
+    {
+        // Arrange - Assembly.Location is virtual on .NET Core, so Moq can mock it
+        var assembly = new Mock<Assembly>();
+        assembly.Setup(a => a.Location).Returns(@"C:\path\to\MyTests.dll");
+
+        // Act
+        string result = SynchronizedSingleSessionVSTestBridgedTestFramework.GetAssemblyPath(assembly.Object);
+
+        // Assert
+        Assert.AreEqual(@"C:\path\to\MyTests.dll", result);
+    }
+
+    [TestMethod]
+    public void GetAssemblyPath_WhenLocationIsEmpty_ReturnsSyntheticPathFromAssemblyName()
+    {
+        // Arrange - simulate Android CoreCLR where Assembly.Location returns ""
+        var assembly = new Mock<Assembly>();
+        assembly.Setup(a => a.Location).Returns(string.Empty);
+        assembly.Setup(a => a.GetName()).Returns(new AssemblyName("MyTests"));
+
+        // Act
+        string result = SynchronizedSingleSessionVSTestBridgedTestFramework.GetAssemblyPath(assembly.Object);
+
+        // Assert
+        Assert.AreEqual("MyTests.dll", result);
+    }
+
+    [TestMethod]
+    public void GetAssemblyPath_WhenLocationIsNull_ReturnsSyntheticPathFromAssemblyName()
+    {
+        // Arrange
+        var assembly = new Mock<Assembly>();
+        assembly.Setup(a => a.Location).Returns((string)null!);
+        assembly.Setup(a => a.GetName()).Returns(new AssemblyName("MyTests"));
+
+        // Act
+        string result = SynchronizedSingleSessionVSTestBridgedTestFramework.GetAssemblyPath(assembly.Object);
+
+        // Assert
+        Assert.AreEqual("MyTests.dll", result);
+    }
+
+    [TestMethod]
+    public void GetAssemblyPath_WhenLocationIsEmpty_AndAssemblyNameIsNull_Throws()
+    {
+        // Arrange
+        var assembly = new Mock<Assembly>();
+        assembly.Setup(a => a.Location).Returns(string.Empty);
+        assembly.Setup(a => a.GetName()).Returns(new AssemblyName());
+
+        // Act & Assert
+        Assert.ThrowsExactly<InvalidOperationException>(
+            () => SynchronizedSingleSessionVSTestBridgedTestFramework.GetAssemblyPath(assembly.Object));
+    }
+
+    [TestMethod]
+    public void GetAssemblyPath_WithDynamicInMemoryAssembly_ReturnsSyntheticPath()
+    {
+        // Arrange - create a real in-memory assembly that has empty Location
+        var assemblyBuilder = AssemblyBuilder.DefineDynamicAssembly(
+            new AssemblyName("InMemoryTestAssembly"),
+            AssemblyBuilderAccess.Run);
+
+        // Verify our assumption: dynamic assemblies have empty Location
+        Assert.AreEqual(string.Empty, assemblyBuilder.Location);
+
+        // Act
+        string result = SynchronizedSingleSessionVSTestBridgedTestFramework.GetAssemblyPath(assemblyBuilder);
+
+        // Assert
+        Assert.AreEqual("InMemoryTestAssembly.dll", result);
+    }
+#endif
+
+    [TestMethod]
+    public void GetAssemblyPath_WithRealAssembly_ReturnsActualLocation()
+    {
+        // Arrange - use the currently executing assembly which has a real file-backed location
+        Assembly assembly = typeof(SynchronizedSingleSessionVSTestBridgedTestFrameworkTests).Assembly;
+
+        // Act
+        string result = SynchronizedSingleSessionVSTestBridgedTestFramework.GetAssemblyPath(assembly);
+
+        // Assert - should return the real path ending with .dll or .exe
+        Assert.AreEqual(assembly.Location, result);
+        Assert.IsTrue(
+            result.EndsWith(".dll", StringComparison.OrdinalIgnoreCase) || result.EndsWith(".exe", StringComparison.OrdinalIgnoreCase));
+    }
+}