diff --git a/doc/changes/dev/13555.bugfix.rst b/doc/changes/dev/13555.bugfix.rst
new file mode 100644
index 00000000000..0ba15a93d88
--- /dev/null
+++ b/doc/changes/dev/13555.bugfix.rst
@@ -0,0 +1 @@
+Fix bug where :func:`mne.io.read_raw_eyelink` raised an error when reading Eyelink files with an empty first recording block, by :newcontrib:`Varun Kasyap Pentamaraju` (:gh:`13555`).
\ No newline at end of file
diff --git a/doc/changes/names.inc b/doc/changes/names.inc
index 77e665ec6ed..cc6800a1b49 100644
--- a/doc/changes/names.inc
+++ b/doc/changes/names.inc
@@ -336,6 +336,7 @@
 .. _Tziona NessAiver: https://github.com/TzionaN
 .. _user27182: https://github.com/user27182
 .. _Valerii Chirkov: https://github.com/vagechirkov
+.. _Varun Kasyap Pentamaraju: https://github.com/varunkasyap
 .. _Velu Prabhakar Kumaravel: https://github.com/vpKumaravel
 .. _Victor Ferat: https://github.com/vferat
 .. _Victoria Peterson: https://github.com/vpeterson
diff --git a/mne/io/eyelink/_utils.py b/mne/io/eyelink/_utils.py
index e66b1855886..2b9f0f1c769 100644
--- a/mne/io/eyelink/_utils.py
+++ b/mne/io/eyelink/_utils.py
@@ -90,7 +90,14 @@ def _parse_eyelink_ascii(
                 raw_extras["dfs"][key], max_time=overlap_threshold
             )
     # ======================== Info for BaseRaw ========================
-    eye_ch_data = raw_extras["dfs"]["samples"][ch_names].to_numpy().T
+    dfs = raw_extras["dfs"]
+
+    if "samples" not in dfs or dfs["samples"].empty:
+        logger.info("No sample data found, creating empty Raw object.")
+        eye_ch_data = np.empty((len(ch_names), 0))
+    else:
+        eye_ch_data = dfs["samples"][ch_names].to_numpy().T
+
     info = _create_info(ch_names, raw_extras)
 
     return eye_ch_data, info, raw_extras
@@ -103,7 +110,7 @@ def _parse_recording_blocks(fname):
     samples lines start with a posix-like string,
     and contain eyetracking sample info. Event Lines
     start with an upper case string and contain info
-    about occular events (i.e. blink/saccade), or experiment
+    about ocular events (i.e. blink/saccade), or experiment
     messages sent by the stimulus presentation software.
     """
     with fname.open() as file:
@@ -182,7 +189,7 @@ def _validate_data(data_blocks: list):
         pupil_units.append(block["info"]["pupil_unit"])
     if "GAZE" in units:
         logger.info(
-            "Pixel coordinate data detected."
+            "Pixel coordinate data detected. "
             "Pass `scalings=dict(eyegaze=1e3)` when using plot"
             " method to make traces more legible."
         )
@@ -369,7 +376,7 @@ def _create_dataframes_for_block(block, apply_offsets):
         df_dict["samples"] = pd.DataFrame(block["samples"])
         df_dict["samples"] = _drop_status_col(df_dict["samples"])  # drop STATUS col
 
-    # dataframe for each type of occular event in this block
+    # dataframe for each type of ocular event in this block
     for event, label in zip(
         ["EFIX", "ESACC", "EBLINK"], ["fixations", "saccades", "blinks"]
     ):
@@ -697,7 +704,7 @@ def _adjust_times(
     -----
     After _parse_recording_blocks, Files with multiple recording blocks will
     have missing timestamps for the duration of the period between the blocks.
-    This would cause the occular annotations (i.e. blinks) to not line up with
+    This would cause the ocular annotations (i.e. blinks) to not line up with
     the signal.
     """
     pd = _check_pandas_installed()
@@ -723,7 +730,7 @@ def _find_overlaps(df, max_time=0.05):
     Parameters
     ----------
     df : pandas.DataFrame
-        Pandas DataFrame with occular events (fixations, saccades, blinks)
+        Pandas DataFrame with ocular events (fixations, saccades, blinks)
     max_time : float (default 0.05)
         Time in seconds. Defaults to .05 (50 ms)
 
diff --git a/mne/io/eyelink/eyelink.py b/mne/io/eyelink/eyelink.py
index 192a5555465..af610e5f43b 100644
--- a/mne/io/eyelink/eyelink.py
+++ b/mne/io/eyelink/eyelink.py
@@ -69,7 +69,7 @@ def read_raw_eyelink(
 
 @fill_doc
 class RawEyelink(BaseRaw):
-    """Raw object from an XXX file.
+    """Raw object from an Eyelink file.
 
     Parameters
     ----------
@@ -123,7 +123,9 @@ def __init__(
             eye_annots = _make_eyelink_annots(
                 self._raw_extras[0]["dfs"], create_annotations, apply_offsets
             )
-        if gap_annots and eye_annots:  # set both
+        if self.n_times == 0:
+            logger.info("No samples found in recording, skipping annotation creation.")
+        elif gap_annots and eye_annots:  # set both
             self.set_annotations(gap_annots + eye_annots)
         elif gap_annots:
             self.set_annotations(gap_annots)
diff --git a/mne/io/eyelink/tests/test_eyelink.py b/mne/io/eyelink/tests/test_eyelink.py
index 596c4468b7a..911a52708a2 100644
--- a/mne/io/eyelink/tests/test_eyelink.py
+++ b/mne/io/eyelink/tests/test_eyelink.py
@@ -523,3 +523,24 @@ def test_href_eye_events(tmp_path):
     # Just check that we actually parsed the Saccade and Fixation events
     assert "saccade" in raw.annotations.description
     assert "fixation" in raw.annotations.description
+
+
+@requires_testing_data
+def test_empty_first_trial(tmp_path):
+    """Test reading a file with an empty first trial."""
+    out_file = tmp_path / "tmp_eyelink.asc"
+    # Use a real eyelink file as base
+    lines = fname.read_text("utf-8").splitlines()
+    # Find first START and END
+    end_idx = next(i for i, line in enumerate(lines) if line.startswith("END"))
+    # Keep headers + START..END but REMOVE all numeric sample lines
+    first_block = []
+    for line in lines[: end_idx + 1]:
+        tokens = line.split()
+        if line.startswith("START") or not tokens or not tokens[0].isdigit():
+            first_block.append(line)
+
+    # Append rest of file (second trial onwards)
+    rest = lines[end_idx + 1 :]
+    out_file.write_text("\n".join(first_block + rest), encoding="utf-8")
+    read_raw_eyelink(out_file)