diff --git a/src/dockerflow/sanic/checks.py b/src/dockerflow/sanic/checks.py
index 332c865..50c8925 100644
--- a/src/dockerflow/sanic/checks.py
+++ b/src/dockerflow/sanic/checks.py
@@ -56,12 +56,17 @@ async def check_redis_connected(redis):
     """
     import aioredis
 
+    if aioredis.__version__.startswith("1."):
+        RedisConnectionError = aioredis.ConnectionClosedError
+    else:
+        RedisConnectionError = aioredis.ConnectionError
+
     errors = []
 
     try:
         with await redis.conn as r:
             result = await r.ping()
-    except aioredis.ConnectionClosedError as e:
+    except RedisConnectionError as e:
         msg = "Could not connect to redis: {!s}".format(e)
         errors.append(Error(msg, id=health.ERROR_CANNOT_CONNECT_REDIS))
     except aioredis.RedisError as e:
diff --git a/tests/constraints/sanic-20.txt b/tests/constraints/sanic-20.txt
index d450454..7c6c3ea 100644
--- a/tests/constraints/sanic-20.txt
+++ b/tests/constraints/sanic-20.txt
@@ -1 +1,3 @@
-Sanic<21
+Sanic>=20,<21
+aioredis<2
+sanic_redis<0.3.0
diff --git a/tests/constraints/sanic-21.txt b/tests/constraints/sanic-21.txt
new file mode 100644
index 0000000..0d223de
--- /dev/null
+++ b/tests/constraints/sanic-21.txt
@@ -0,0 +1 @@
+Sanic>=21,<22
diff --git a/tests/constraints/sanic-22.txt b/tests/constraints/sanic-22.txt
new file mode 100644
index 0000000..97479fa
--- /dev/null
+++ b/tests/constraints/sanic-22.txt
@@ -0,0 +1 @@
+Sanic>=22,<23
diff --git a/tests/requirements/sanic-20.txt b/tests/requirements/sanic-20.txt
new file mode 100644
index 0000000..e11c6f2
--- /dev/null
+++ b/tests/requirements/sanic-20.txt
@@ -0,0 +1,7 @@
+# these are constrained by the files in tests/constraints/*.txt
+# to support a triple stack Django/Flask/Sanic
+aiohttp
+aioredis
+Sanic
+sanic_redis
+uvloop>=0.14.0rc1
diff --git a/tests/requirements/sanic.txt b/tests/requirements/sanic.txt
index 41ec1d2..20ffec4 100644
--- a/tests/requirements/sanic.txt
+++ b/tests/requirements/sanic.txt
@@ -1,7 +1,8 @@
 # these are constrained by the files in tests/constraints/*.txt
 # to support a triple stack Django/Flask/Sanic
 aiohttp
-aioredis<2.0.0
+aioredis
 Sanic
-sanic_redis<0.3.0
+sanic_redis
+sanic-testing
 uvloop>=0.14.0rc1
diff --git a/tests/sanic/test_sanic.py b/tests/sanic/test_sanic.py
index f3682a2..b3c4be5 100644
--- a/tests/sanic/test_sanic.py
+++ b/tests/sanic/test_sanic.py
@@ -3,11 +3,11 @@
 # file, you can obtain one at http://mozilla.org/MPL/2.0/.
 import functools
 import logging
-import socket
+import uuid
 
 import aioredis
 import pytest
-import sanic.testing
+import sanic
 import sanic_redis.core
 from sanic import Sanic, response
 from sanic_redis import SanicRedis
@@ -15,9 +15,14 @@
 from dockerflow import health
 from dockerflow.sanic import Dockerflow, checks
 
+if sanic.__version__.startswith("20."):
+    from sanic.testing import SanicTestClient
+else:
+    from sanic_testing.testing import SanicTestClient
+
 
 class FakeRedis:
-    def __init__(self, error=None, **kw):
+    def __init__(self, *args, error=None, **kw):
         self.error = error
 
     def __await__(self):
@@ -30,7 +35,7 @@ def __enter__(self):
     def __exit__(self, *exc_info):
         pass
 
-    def close(self):
+    async def close(self):
         pass
 
     async def wait_closed(self):
@@ -38,7 +43,11 @@ async def wait_closed(self):
 
     async def ping(self):
         if self.error == "connection":
-            raise aioredis.ConnectionClosedError("fake")
+            if aioredis.__version__.startswith("1."):
+                RedisConnectionError = aioredis.ConnectionClosedError
+            else:
+                RedisConnectionError = aioredis.ConnectionError
+            raise RedisConnectionError("fake")
         elif self.error == "redis":
             raise aioredis.RedisError("fake")
         elif self.error == "malformed":
@@ -47,13 +56,20 @@ async def ping(self):
             return b"PONG"
 
 
-async def fake_redis(**kw):
-    return FakeRedis(**kw)
+class FakeRedis1(FakeRedis):
+    def close(self):
+        pass
+
+
+async def fake_redis(*args, **kw):
+    if aioredis.__version__.startswith("1."):
+        return FakeRedis1(*args, **kw)
+    return FakeRedis(*args, **kw)
 
 
 @pytest.fixture(scope="function")
 def app():
-    app = Sanic("dockerflow")
+    app = Sanic(f"dockerflow-{uuid.uuid4().hex}")
 
     @app.route("/")
     async def root(request):
@@ -77,30 +93,27 @@ def dockerflow_redis(app):
 
 @pytest.fixture
 def test_client(app):
-    # Create SanicTestClient manually and provide a socket object instead of host
-    # and port when calling Sanic.run in order to avoid parallel test failures
-    # caused by Sanic.test_client bindngs to a static port
-    s = socket.socket()
-    s.bind((sanic.testing.HOST, 0))
-    try:
-        # initialize test_client with socket's port
-        test_client = sanic.testing.SanicTestClient(app, s.getsockname()[1])
-        # override app.run to drop host and port in favor of socket
-        run = app.run
-        app.run = lambda host, port, **kw: run(sock=s, **kw)
-        # yield test_client
-        yield test_client
-    finally:
-        s.close()
+    return SanicTestClient(app)
 
 
-def test_instantiating(app):
+@pytest.mark.skipif(not sanic.__version__.startswith("20."), reason="requires sanic 20")
+def test_instantiating_sanic_20(app):
     dockerflow = Dockerflow()
     assert "dockerflow.heartbeat" not in app.router.routes_names
     dockerflow.init_app(app)
     assert "dockerflow.heartbeat" in app.router.routes_names
 
 
+@pytest.mark.skipif(
+    sanic.__version__.startswith("20."), reason="requires sanic 21 or later"
+)
+def test_instantiating(app):
+    Dockerflow()
+    assert ("__heartbeat__",) not in app.router.routes_all
+    Dockerflow(app)
+    assert ("__heartbeat__",) in app.router.routes_all
+
+
 def test_version_exists(dockerflow, mocker, test_client, version_content):
     mocker.patch.object(dockerflow, "_version_callback", return_value=version_content)
     _, response = test_client.get("/__version__")
@@ -178,7 +191,10 @@ async def warning_check2():
 
 def test_redis_check(dockerflow_redis, mocker, test_client):
     assert "check_redis_connected" in dockerflow_redis.checks
-    mocker.patch.object(sanic_redis.core, "create_redis_pool", fake_redis)
+    if aioredis.__version__.startswith("1."):
+        mocker.patch.object(sanic_redis.core, "create_redis_pool", fake_redis)
+    else:
+        mocker.patch.object(sanic_redis.core, "from_url", fake_redis)
     _, response = test_client.get("/__heartbeat__")
     assert response.status == 200
     assert response.json["status"] == "ok"
@@ -198,7 +214,10 @@ def test_redis_check(dockerflow_redis, mocker, test_client):
 def test_redis_check_error(dockerflow_redis, mocker, test_client, error, messages):
     assert "check_redis_connected" in dockerflow_redis.checks
     fake_redis_error = functools.partial(fake_redis, error=error)
-    mocker.patch.object(sanic_redis.core, "create_redis_pool", fake_redis_error)
+    if aioredis.__version__.startswith("1."):
+        mocker.patch.object(sanic_redis.core, "create_redis_pool", fake_redis_error)
+    else:
+        mocker.patch.object(sanic_redis.core, "from_url", fake_redis_error)
     _, response = test_client.get("/__heartbeat__")
     assert response.status == 500
     assert response.json["status"] == "error"
diff --git a/tox.ini b/tox.ini
index 7f04c32..378e2a4 100644
--- a/tox.ini
+++ b/tox.ini
@@ -7,7 +7,8 @@ envlist =
     py{37,38,39,310}-dj32
     py{38,39,310}-dj{40}
     py{37,38,39,310}-fl{012,10,11,20,21}
-    py{37,38,39}-s{20}
+    py{37,38,39}-s20
+    py{37,38,39,310}-s{21,22}
 
 [gh-actions]
 python =
@@ -26,7 +27,8 @@ deps =
     -rtests/requirements/default.txt
     dj{32,40}: -rtests/requirements/django.txt
     fl{012,10,11,20,21}: -rtests/requirements/flask.txt
-    s{20}: -rtests/requirements/sanic.txt
+    s20: -rtests/requirements/sanic-20.txt
+    s{21,22}: -rtests/requirements/sanic.txt
     dj32: -ctests/constraints/django-3.2.txt
     dj40: -ctests/constraints/django-4.0.txt
     fl012: -ctests/constraints/flask-0.12.txt
@@ -35,11 +37,13 @@ deps =
     fl20: -ctests/constraints/flask-2.0.txt
     fl21: -ctests/constraints/flask-2.0.txt
     s20: -ctests/constraints/sanic-20.txt
+    s21: -ctests/constraints/sanic-21.txt
+    s22: -ctests/constraints/sanic-22.txt
 commands =
     python --version
     dj{32,40}: pytest tests/core/ tests/django --nomigrations {posargs:}
     fl{012,10,11,20,21}: pytest tests/core/ tests/flask/ {posargs:}
-    s{20}: pytest tests/core/ tests/sanic/ {posargs:}
+    s{20,21,22}: pytest tests/core/ tests/sanic/ {posargs:}
 
 [testenv:py38-docs]
 basepython = python3.8