diff --git a/lib/private/App/AppManager.php b/lib/private/App/AppManager.php
index 88044fbf7b6f5..82dbbc65089c9 100644
--- a/lib/private/App/AppManager.php
+++ b/lib/private/App/AppManager.php
@@ -543,6 +543,11 @@ public function enableApp(string $appId, bool $forceEnable = false): void {
 			ManagerEvent::EVENT_APP_ENABLE, $appId
 		));
 		$this->clearAppsCache();
+
+		if (function_exists('apcu_delete') && class_exists(\APCUIterator::class)) {
+			$apcuPrefix = 'composer_autoload_' . md5(\OC::$SERVERROOT . '_' . \OC::$VERSION_MTIME);
+			apcu_delete(new \APCUIterator('#^' . $apcuPrefix . '#'));
+		}
 	}
 
 	/**