diff --git a/.coveragerc b/.coveragerc
deleted file mode 100644
index 5687b73..0000000
--- a/.coveragerc
+++ /dev/null
@@ -1,9 +0,0 @@
-[run]
-branch=True
-source=pytest_trio
-
-[report]
-precision = 1
-exclude_lines =
-  pragma: no cover
-  abc.abstractmethod
diff --git a/ci.sh b/ci.sh
index aae8b3c..0a6c4d6 100755
--- a/ci.sh
+++ b/ci.sh
@@ -23,11 +23,11 @@ function curl-harder() {
 }
 
 
-python -m pip install -U pip setuptools wheel
+python -m pip install -U pip build
 python -m pip --version
 
-python setup.py sdist --formats=zip
-python -m pip install dist/*.zip
+python -m build
+python -m pip install dist/*.whl
 
 if [ "$CHECK_FORMATTING" = "1" ]; then
     pip install black
diff --git a/pyproject.toml b/pyproject.toml
index 407fb8b..48270b0 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -1,3 +1,67 @@
+[build-system]
+requires = ["setuptools >= 64"]
+build-backend = "setuptools.build_meta"
+
+[project]
+name = "pytest-trio"
+dynamic = ["version"]
+authors = [
+  { name="Emmanuel Leblond", email="emmanuel.leblond@gmail.com" },
+]
+description = "Pytest plugin for trio"
+readme = {file = "README.md", content-type = "text/markdown"}
+license = {file = "LICENSE"}
+requires-python = ">=3.8"
+classifiers = [
+    "Development Status :: 4 - Beta",
+    "License :: OSI Approved :: MIT License",
+    "License :: OSI Approved :: Apache Software License",
+    "Natural Language :: English",
+    "Programming Language :: Python :: 3",
+    "Programming Language :: Python :: 3.8",
+    "Programming Language :: Python :: 3.9",
+    "Programming Language :: Python :: 3.10",
+    "Programming Language :: Python :: 3.11",
+    "Programming Language :: Python :: 3.12",
+    "Programming Language :: Python :: 3 :: Only",
+    "Programming Language :: Python :: Implementation :: CPython",
+    "Programming Language :: Python :: Implementation :: PyPy",
+    "Operating System :: POSIX :: Linux",
+    "Operating System :: MacOS :: MacOS X",
+    "Operating System :: Microsoft :: Windows",
+    "Operating System :: OS Independent",
+    "Topic :: System :: Networking",
+    "Topic :: Software Development :: Testing",
+    "Framework :: Hypothesis",
+    "Framework :: Pytest",
+    "Framework :: Trio",
+]
+keywords = [
+    "async",
+    "pytest",
+    "testing",
+    "trio",
+]
+dependencies = [
+    "trio >= 0.25.1",  # for upstream Hypothesis integration
+    "outcome >= 1.1.0",
+    "pytest >= 7.2.0",  # for ExceptionGroup support
+]
+
+[tool.setuptools.dynamic]
+version = {attr = "pytest_trio._version.__version__"}
+
+[project.urls]
+"Homepage" = "https://github.com/python-trio/pytest-trio"
+"Source" = "https://github.com/python-trio/pytest-trio"
+"Bug Tracker" = "https://github.com/python-trio/pytest-trio/issues"
+
+[project.entry-points.pytest11]
+trio = "pytest_trio.plugin"
+
+[tool.setuptools.packages]
+find = {namespaces = false}
+
 [tool.towncrier]
 package = "pytest_trio"
 filename = "docs/source/history.rst"
@@ -5,3 +69,30 @@ directory = "newsfragments"
 title_format = "pytest-trio {version} ({project_date})"
 underlines = ["-", "~", "^"]
 issue_format = "`#{issue} <https://github.com/python-trio/pytest-trio/issues/{issue}>`__"
+
+[tool.coverage.run]
+branch = true
+source_pkgs = ["pytest_trio"]
+
+[tool.coverage.report]
+precision = 1
+skip_covered = true
+exclude_lines = [
+    "pragma: no cover",
+    "abc.abstractmethod",
+    "if TYPE_CHECKING.*:",
+    "if _t.TYPE_CHECKING:",
+    "if t.TYPE_CHECKING:",
+    "@overload",
+    'class .*\bProtocol\b.*\):',
+    "raise NotImplementedError",
+]
+partial_branches = [
+    "pragma: no branch",
+    "if not TYPE_CHECKING:",
+    "if not _t.TYPE_CHECKING:",
+    "if not t.TYPE_CHECKING:",
+    "if .* or not TYPE_CHECKING:",
+    "if .* or not _t.TYPE_CHECKING:",
+    "if .* or not t.TYPE_CHECKING:",
+]
diff --git a/pytest_trio/_version.py b/pytest_trio/_version.py
index a149830..2333e2d 100644
--- a/pytest_trio/_version.py
+++ b/pytest_trio/_version.py
@@ -1,3 +1,3 @@
-# This file is imported from __init__.py and exec'd from setup.py
+# This file is imported from __init__.py and parsed by setuptools
 
 __version__ = "0.8.0+dev"
diff --git a/setup.py b/setup.py
deleted file mode 100644
index 997b19a..0000000
--- a/setup.py
+++ /dev/null
@@ -1,50 +0,0 @@
-from setuptools import setup, find_packages
-
-exec(open("pytest_trio/_version.py", encoding="utf-8").read())
-
-LONG_DESC = open("README.rst", encoding="utf-8").read()
-
-setup(
-    name="pytest-trio",
-    version=__version__,
-    description="Pytest plugin for trio",
-    url="https://github.com/python-trio/pytest-trio",
-    long_description=open("README.rst").read(),
-    author="Emmanuel Leblond",
-    author_email="emmanuel.leblond@gmail.com",
-    license="MIT OR Apache-2.0",
-    packages=find_packages(),
-    entry_points={"pytest11": ["trio = pytest_trio.plugin"]},
-    install_requires=[
-        "trio >= 0.25.1",  # for upstream Hypothesis integration
-        "outcome >= 1.1.0",
-        "pytest >= 7.2.0",  # for ExceptionGroup support
-    ],
-    keywords=[
-        "async",
-        "pytest",
-        "testing",
-        "trio",
-    ],
-    python_requires=">=3.7",
-    classifiers=[
-        "License :: OSI Approved :: MIT License",
-        "License :: OSI Approved :: Apache Software License",
-        "Operating System :: POSIX :: Linux",
-        "Operating System :: MacOS :: MacOS X",
-        "Operating System :: Microsoft :: Windows",
-        "Programming Language :: Python :: 3 :: Only",
-        "Programming Language :: Python :: 3.8",
-        "Programming Language :: Python :: 3.9",
-        "Programming Language :: Python :: 3.10",
-        "Programming Language :: Python :: 3.11",
-        "Programming Language :: Python :: 3.12",
-        "Programming Language :: Python :: Implementation :: CPython",
-        "Programming Language :: Python :: Implementation :: PyPy",
-        "Topic :: System :: Networking",
-        "Topic :: Software Development :: Testing",
-        "Framework :: Hypothesis",
-        "Framework :: Pytest",
-        "Framework :: Trio",
-    ],
-)