diff --git a/ofrak_core/CHANGELOG.md b/ofrak_core/CHANGELOG.md
index ee1704b28..f0554df21 100644
--- a/ofrak_core/CHANGELOG.md
+++ b/ofrak_core/CHANGELOG.md
@@ -14,6 +14,7 @@ The format is based on [Keep a Changelog](https://keepachangelog.com/en/1.0.0/)
 
 ### Fixed
 - Fix `Resource.get_attributes` docstring to match implementation ([#692](https://github.com/redballoonsecurity/ofrak/pull/692))
+- Document `CodeRegion` requirement to be descendant of `Program` for disassembly ([#696](https://github.com/redballoonsecurity/ofrak/pull/696))
 - Fix GUI serialization of enum values and script creator generating invalid Python syntax for enum values
 - `build_image.py` uses `OFRAK_DIR` from `extra_build_args` to identify `pytest_ofrak` location for develop builds ([#657](https://github.com/redballoonsecurity/ofrak/pull/657/))
 
diff --git a/ofrak_core/src/ofrak/core/code_region.py b/ofrak_core/src/ofrak/core/code_region.py
index d437b051a..e7aea8b27 100644
--- a/ofrak_core/src/ofrak/core/code_region.py
+++ b/ofrak_core/src/ofrak/core/code_region.py
@@ -9,6 +9,9 @@
 class CodeRegion(MemoryRegion):
     """
     A memory region within a [program][ofrak.core.program.Program] that contains executable code.
+
+    Must be a descendant of a Program for disassembly, as disassembler backends use the ancestor
+    Program to locate their analysis context.
     """