diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml
index 70cacf7b..44c27b70 100644
--- a/.github/workflows/test.yml
+++ b/.github/workflows/test.yml
@@ -8,7 +8,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        python-version: [3.5, 3.6, 3.7, 3.8, 3.9, 3.10-dev, pypy3]
+        python-version: [3.5, 3.6, 3.7, 3.8, 3.9, "3.10", pypy3]
 
     steps:
       - uses: actions/checkout@v2
diff --git a/NEWS b/NEWS
index df49f5e8..cf7f84f0 100644
--- a/NEWS
+++ b/NEWS
@@ -3,6 +3,15 @@ testtools NEWS
 
 Changes and improvements to testtools_, grouped by release.
 
+NEXT
+~~~~
+
+Improvements
+------------
+
+* Add support for Python 3.10.
+  (Jürgen Gmach)
+
 2.5.0
 ~~~~~
 
diff --git a/scripts/all-pythons b/scripts/all-pythons
index 6996a447..0fbe0102 100755
--- a/scripts/all-pythons
+++ b/scripts/all-pythons
@@ -89,5 +89,5 @@ def now():
 if __name__ == '__main__':
     sys.path.append(ROOT)
     result = TestProtocolClient(sys.stdout)
-    for version in '3.5 3.6 3.7 3.8 3.9'.split():
+    for version in '3.5 3.6 3.7 3.8 3.9 3.10'.split():
         run_for_python(version, result, sys.argv[1:])
diff --git a/setup.cfg b/setup.cfg
index f252785b..c31f8f3c 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -17,6 +17,7 @@ classifier =
     Programming Language :: Python :: 3.7
     Programming Language :: Python :: 3.8
     Programming Language :: Python :: 3.9
+    Programming Language :: Python :: 3.10
     Programming Language :: Python :: 3 :: Only
     Programming Language :: Python :: Implementation :: CPython
     Programming Language :: Python :: Implementation :: PyPy
diff --git a/testtools/tests/test_testresult.py b/testtools/tests/test_testresult.py
index a9db0e27..4fbf15d1 100644
--- a/testtools/tests/test_testresult.py
+++ b/testtools/tests/test_testresult.py
@@ -2667,16 +2667,19 @@ def test_syntax_error(self):
         """Syntax errors should still have fancy special-case formatting"""
         if platform.python_implementation() == "PyPy":
             spaces = '           '
+            marker = '^'
         elif sys.version_info >= (3, 10):
             spaces = '        '
+            marker = '^^^'
         else:
             spaces = '          '
+            marker = '^'
         textoutput = self._test_external_case("exec ('f(a, b c)')")
         self.assertIn(self._as_output(
             '  File "<string>", line 1\n'
             '    f(a, b c)\n'
             + ' ' * self._error_on_character +
-            spaces + '^\n'
+            spaces + marker + '\n'
             'SyntaxError: '
             ), textoutput)
 
diff --git a/tox.ini b/tox.ini
index 5e9ab125..0416e06e 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,5 +1,5 @@
 [tox]
-envlist = py35,py36,py37,py38,py39,310,pypy3
+envlist = py35,py36,py37,py38,py39,py310,pypy3
 minversion = 1.6
 
 [testenv]