diff --git a/src/uu/stdbuf/build.rs b/src/uu/stdbuf/build.rs
index 66f702c4597..aa2692cb512 100644
--- a/src/uu/stdbuf/build.rs
+++ b/src/uu/stdbuf/build.rs
@@ -14,6 +14,7 @@ use std::process::Command;
     target_os = "android",
     target_os = "freebsd",
     target_os = "netbsd",
+    target_os = "openbsd",
     target_os = "dragonfly"
 ))]
 mod platform {
diff --git a/src/uu/stdbuf/src/libstdbuf/src/libstdbuf.rs b/src/uu/stdbuf/src/libstdbuf/src/libstdbuf.rs
index d99509880b7..3ef7473bf79 100644
--- a/src/uu/stdbuf/src/libstdbuf/src/libstdbuf.rs
+++ b/src/uu/stdbuf/src/libstdbuf/src/libstdbuf.rs
@@ -27,7 +27,15 @@ pub unsafe extern "C" fn __stdbuf_get_stdin() -> *mut FILE {
         unsafe { __stdinp() }
     }
 
-    #[cfg(not(any(target_os = "macos", target_os = "freebsd")))]
+    #[cfg(target_os = "openbsd")]
+    {
+        unsafe extern "C" {
+            static mut __stdin: *mut FILE;
+        }
+        unsafe { __stdin }
+    }
+
+    #[cfg(not(any(target_os = "macos", target_os = "freebsd", target_os = "openbsd")))]
     {
         unsafe extern "C" {
             static mut stdin: *mut FILE;
@@ -48,7 +56,15 @@ pub unsafe extern "C" fn __stdbuf_get_stdout() -> *mut FILE {
         unsafe { __stdoutp() }
     }
 
-    #[cfg(not(any(target_os = "macos", target_os = "freebsd")))]
+    #[cfg(target_os = "openbsd")]
+    {
+        unsafe extern "C" {
+            static mut __stdout: *mut FILE;
+        }
+        unsafe { __stdout }
+    }
+
+    #[cfg(not(any(target_os = "macos", target_os = "freebsd", target_os = "openbsd")))]
     {
         unsafe extern "C" {
             static mut stdout: *mut FILE;
@@ -69,7 +85,15 @@ pub unsafe extern "C" fn __stdbuf_get_stderr() -> *mut FILE {
         unsafe { __stderrp() }
     }
 
-    #[cfg(not(any(target_os = "macos", target_os = "freebsd")))]
+    #[cfg(target_os = "openbsd")]
+    {
+        unsafe extern "C" {
+            static mut __stderr: *mut FILE;
+        }
+        unsafe { __stderr }
+    }
+
+    #[cfg(not(any(target_os = "macos", target_os = "freebsd", target_os = "openbsd")))]
     {
         unsafe extern "C" {
             static mut stderr: *mut FILE;
diff --git a/src/uu/stdbuf/src/stdbuf.rs b/src/uu/stdbuf/src/stdbuf.rs
index 639c3ffff07..52824ad5e61 100644
--- a/src/uu/stdbuf/src/stdbuf.rs
+++ b/src/uu/stdbuf/src/stdbuf.rs
@@ -35,6 +35,7 @@ mod options {
         target_os = "android",
         target_os = "freebsd",
         target_os = "netbsd",
+        target_os = "openbsd",
         target_os = "dragonfly"
     )
 ))]
@@ -82,6 +83,7 @@ enum ProgramOptionsError {
     target_os = "android",
     target_os = "freebsd",
     target_os = "netbsd",
+    target_os = "openbsd",
     target_os = "dragonfly"
 ))]
 fn preload_strings() -> UResult<(&'static str, &'static str)> {
@@ -98,6 +100,7 @@ fn preload_strings() -> UResult<(&'static str, &'static str)> {
     target_os = "android",
     target_os = "freebsd",
     target_os = "netbsd",
+    target_os = "openbsd",
     target_os = "dragonfly",
     target_vendor = "apple"
 )))]