Welcome to PARASECT: Predictive Algorithm for Resolving A-domain Specificity featurising Enzyme and Compound in Tandem. Detect NRPS AMP-binding domains from an amino acid sequence and predict their substrate specificity profile.
You can find a live version of the web application here.
Browse the data that PARAS and PARASECT were trained on here.
Do you have new datapoints that you think PARAS/PARASECT could benefit from in future versions? Submit your data here.
The trained models for PARAS and PARASECT can be found on Zenodo here.
To install PARAS/PARASECT on the command line, run:
conda create -n paras python=3.9
conda activate paras
pip install paras
conda install -c bioconda hmmer
conda install -c bioconda hmmer2
conda install -c bioconda muscle==3.8.1551
For usage instructions, see our wiki. Note that the command line tool will download the models from zenodo upon the first run.