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yank-restraints

Benchmarking project testing different restraints schemes for free energy calculations with YANK

This repository houses all the files for our project benchmarking the use of restraints binding free energy calculations with YANK, as detailed in our outline. Here you will find all the files needed to run YANK simulations on host-guest (cyclodextrin-cyclopentanol) and T4 lysozyme (T4 lysozyme L99A-toluene) complexes.

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Benchmarking project testing different restraints schemes for free energy calculations with Yank

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