BetaReview: Day 1 lab xULNs not at baseline (non-zero values) #176
Description
Description:
User observed that some Day 1 lab values expressed as multiples of upper limit of normal (xULN) are not 0, suggesting Day 1 may not represent true baseline. Questions raised:
- Are Day 1 values the true baselines?
- Were earlier screening baselines used instead?
- What are the true baselines for all labs and their corresponding study days?
Action Items:
- Reproduce the issue with user's data or sample data
- Investigate baseline calculation logic
- Verify which study day is being used as baseline reference
- If not reproducible, request specific dataset/parameters from user
- Determine if this is a data issue or calculation bug
- Document expected baseline behavior in user documentation
- Fix calculation if bug is confirmed
Additional Context:
This could indicate a fundamental issue with how baseline values are identified or calculated in the application.