@d33bs - consider applying pycytominer-transform to the existing SQLite data here to test your approach with real world data.
We would be particularly interested in comparing the results from pycytominer.cyto_utils.cells.SingleCells to the pycytominer-transform derived parquet file.
More details about the SingleCells processing is here: https://github.com/WayScience/NF1_SchwannCell_data/blob/5536d86330aba0f66c74e2bd44c6e82ed1c985f9/4_processing_features/extract_single_cell_features.ipynb