Update in-process named mutexes are now implemented since #55199 For WebAssembly and ios/Android this is sufficient.
We may still want to implement inter-process named mutex emulation using a mechanism similar to https://github.com/dotnet/runtime/blob/main/src/coreclr/pal/src/include/pal/mutex.hpp
As discussed in #55199 (comment) the approach would be to cherrypick the support from the CoreCLR PAL into a src/libraries PAL implementation.
Original
Some tests rely on this behavior, and so now with Mono migrating implementations they are temporarily disabled.