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Mapping file must be the same length as the template file.

Status: Open.

#671 In google-deepmind/alphafold3;

· wangb799 opened on May 16, 2026

Inaccurate modelling of dihydrouridine RNA modifications

questionFurther information is requestedFurther information is requested

Status: Open.

#667 In google-deepmind/alphafold3;

· AlexHurtado2000 opened on May 12, 2026

How to turn off templates on AF3 server?

questionFurther information is requestedFurther information is requested

Status: Open.

#666 In google-deepmind/alphafold3;

· HenriettaHolze opened on May 11, 2026

Document using user-provided CCDs for chain-internal non-canonical amino acids

documentationImprovements or additions to documentationImprovements or additions to documentation

enhancementNew feature or requestNew feature or request

Status: Open.

#661 In google-deepmind/alphafold3;

· Fred-Jing opened on Apr 27, 2026

Question/Request: Apple Silicon support

enhancementNew feature or requestNew feature or request

Status: Open.

#657 In google-deepmind/alphafold3;

· SuhasSrinivasan opened on Apr 21, 2026

O1 atom incorrectly dropped from non-linking saccharides/glycans

bugSomething isn't workingSomething isn't working

Status: Open.

#650 In google-deepmind/alphafold3;

· Jonas-Wilhelm opened on Apr 14, 2026

AF3 runtime higher than reported for pool of proteins with 5000 tokens

questionFurther information is requestedFurther information is requested

Status: Open.

#609 In google-deepmind/alphafold3;

· karchern opened on Jan 30, 2026

OOM issues with 4608 and 5120 buckets

questionFurther information is requestedFurther information is requested

Status: Open.

#576 In google-deepmind/alphafold3;

· gdlampe opened on Dec 19, 2025

AF3 cannot predict correct ligand isomer even using userCDD

questionFurther information is requestedFurther information is requested

Status: Open.

#527 In google-deepmind/alphafold3;

· antonielgomes opened on Sep 26, 2025

Unified memory for extra large systems - rematerialization problems

questionFurther information is requestedFurther information is requested

Status: Open.

#432 In google-deepmind/alphafold3;

· GorgetteGorg opened on May 28, 2025

5746 tokens job: RESOURCE_EXHAUSTED (H100 80G, despite unified memory, jax flag and increase bucket size)

questionFurther information is requestedFurther information is requested

Status: Open.

#341 In google-deepmind/alphafold3;

· GitCeliniHub opened on Mar 9, 2025

Adding Docker image to container registry

enhancementNew feature or requestNew feature or request

Status: Open.

#322 In google-deepmind/alphafold3;

· VRehnberg opened on Feb 24, 2025