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heleensev/CardioDiscover

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About

This application will enable researchers to automatically discover target genes from multi-phenotype summary GWAS datasets, for future assays. The code is specifically developed for cardiovascular phenotypes, but will be largely applicable to other types of GWAS.

Structure

The application consists of several modules:

  • GWAS parser
  • RNAseq parser
  • SNP conformer
  • Statistical tester
  • Gene mapper
  • Drugability tester
  • SNP ranker

Flowchart

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Current State

  • GWASParser
  • RNAseq parser
  • SNP conformer
  • Statistical tester
  • Gene mapper
  • Drugability tester
  • SNP ranker

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